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内部出版物
CNKI学位论文(7)
在“
Elsevier电子期刊
”中,
命中:
3
条,耗时:小于0.01 秒
在所有数据库中总计命中:
7
条
1.
Identification of GNE-293, a potent and selective PI3K¦Ä inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity
作者:
Brian S. Safina
;
Zachary K. Sweeney
;
Jun Li
;
Bryan K. Chan
;
Angelina Bisconte
;
Diane Carrera
;
Georgette Castanedo
;
Michael Flagella
;
Robert Heald
;
Cristina Lewis
;
Jeremy M. Murray
;
Jim
Nonomiya
;
Jodie Pang
;
Steve Price
;
Karin Reif
;
Laurent Salphati
;
Eileen M. Seward
;
Binqing Wei
;
Daniel P. Sutherlin
关键词:
PI3K ¦Ä
;
PI3K isoform selectivity
;
B-cell inhibition
;
Genotox
;
HCA
;
MNT
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
A hit to lead discovery of novel N-methylated imidazolo-, pyrrolo-, and pyrazolo-pyrimidines as potent and selective mTOR inhibitors
作者:
Wendy Lee
;
Daniel F. Ortwine
;
Philippe Bergeron
;
Kevin Lau
;
Lichuan Lin
;
Shiva Malek
;
Jim
Nonomiya
;
Zhonghua Pei
;
Kirk D. Robarge
;
Stephen Schmidt
;
Steve Sideris
;
Joseph P. Lyssikatos
关键词:
Mammalian target of rapamycin
;
mTOR kinase inhibitors
;
PI3K/Akt/mTOR pathway
;
Structure based design
;
Oncology
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
3.
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor
作者:
Timothy P. Heffron
;
Megan Berry
;
Georgette Castanedo
;
Christine Chang
;
Irina Chuckowree
;
Jennafer Dotson
;
Adrian Folkes
;
Janet Gunzner
;
John D. Lesnick
;
Cristina Lewis
;
Simon Mathieu
;
Jim
Nonomiya
;
Al
关键词:
PI3K
;
mTOR
;
Kinase inhibitors
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
1
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