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内部出版物
CNKI学位论文(2)
知网期刊论文(2)
在“
Elsevier电子期刊
”中,
命中:
7
条,耗时:小于0.01 秒
在所有数据库中总计命中:
4
条
1.
Effects of sublingual immunotherapy in a murine asthma model sensitized by intranasal administration of house dust mite extracts
作者:
Kenjiro Shima
a
;
Toshiyuki Koya
a
;
tkoya@med.niigata-u.ac.jp
;
Keisuke Tsukioka
a
;
Takuro Sakagami
a
;
Takashi Hasegawa
b
;
Chiharu Fukano
c
;
Katsuyo
Ohashi
-Doi
c
;
Satoshi Watanabe
a
;
Eiichi Suzuki
b
;
Toshiaki Kikuchi
a
关键词:
Airway hyperresponsiveness
;
Animal model
;
Bronchial asthma
;
House dust mites
;
Sublingual immunotherapy
刊名:Allergology International
出版年:2017
2.
Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure-activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives
作者:
Shigeo Hayashi
;
Shigeo_Hayashi@nifty.com" class="auth_mail" title="E-mail the corresponding author
;
Katsuyo
Ohashi
;
Sachiko Mihara
;
Eriko Nakata
;
Chie Emoto
;
Atsuko Ohta
关键词:
Nociceptin/Orphanin FQ (N/OFQ)
;
Human NOP (ORL1) receptor selective antagonist
;
Multisite interactions with NOP receptor
;
Metabolic stability
;
HERG potassium ion channel binding
;
Prolong QT interval issues
刊名:European Journal of Medicinal Chemistry
出版年:2016
3.
Discovery of 1-(¦Â-amino substituted-¦Â-alanyl)-N,N-dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: Efficient design, synthesis, and structure-activity relationship studies
作者:
Shigeo Hayashi
;
Shigeo_Hayashi@nifty.com
;
Katsuyo
Ohashi
;
Eriko Nakata
;
Chie Emoto
关键词:
Nociceptin/Orphanin FQ (N/OFQ)
;
NOP (ORL1) receptor antagonist
;
NOP receptor selectivity
;
Half-life in HLM
刊名:European Journal of Medicinal Chemistry
出版年:2012
4.
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: De
作者:
Shigeo Hayashi
;
Eriko Nakata
;
Asato Morita
;
Kunihiko Mizuno
;
Kenzo Yamamura
;
Aki Kato
;
Katsuyo
Ohashi
关键词:
GPCR
;
Nociceptin/orphanin FQ
;
NOP receptor-selective full agonist
;
{
;
1-[4-(2-{
;
Hexahydropyrrolo[3
;
4-
c
]pyrrol-2(1
H
)-yl}-1
H
-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol (HPCOM)
;
Systemically active analgesic for the trea
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
5.
Pregabalin inhibits accelerated defecation and decreased colonic nociceptive threshold in sensitized rats
作者:
Katsuyo
Ohashi
-Doi
;
Jeremy D. Gale
;
Yoichi Kurebayashi
关键词:
α
;
2
δ
;
calcium channel ligand
;
Irritable bowel syndrome
;
Pregabalin
;
Defecation
;
Visceral hypersensitivity
刊名:European Journal of Pharmacology
出版年:2010
6.
Abolishment of TNBS-induced visceral hypersensitivity in mast cell deficient rats
作者:
Katsuyo
Ohashi
;
Yasushi Sato
;
Mitsuhisa Kawai
;
Yoichi Kurebayashi
关键词:
IBS
;
Mast cell deficient rats
;
Myeloperoxidase
;
TNBS
;
Visceral hypersensitivity
刊名:Life Sciences
出版年:2008
7.
Virol A, a toxic trans-polyacetylenic alcohol of Cicuta virosa, selectively inhibits the GABA-induced Cl
−
current in acutely dissociated rat hippocampal CA1 neurons
作者:
Uwai
;
Koji
;
Ohashi
;
Katsuyo
;
Takaya
;
Yoshiaki
;
Oshima
;
Yoshiteru
;
Furukawa
;
Ken-ichi
;
Yamagata
;
Kanato
;
et. al.
关键词:
Neurotransmitters
;
modulators
;
transporters
;
and receptors
;
GABA receptors
;
GABA
A
receptor
;
Virol A
;
Hippocampal neuron
刊名:Brain Research
出版年:2001
1
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2008年(1)
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