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内部出版物
CNKI学位论文(76)
知网期刊论文(4)
在“
Elsevier电子期刊
”中,
命中:
46
条,耗时:小于0.01 秒
在所有数据库中总计命中:
80
条
1.
Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor ¦Ã agonist
作者:
Anna Ohtera
;
Yusaku Miyamae
;
Naomi Nakai
;
Atsushi Kawachi
;
Kiyokazu Kawada
;
Junkyu Han
;
Hiroko Isoda
;
Mohamed Neffati
;
Toru Akita
;
Kazuhiro
Maejima
;
Seiji Masuda
;
Taiho Kambe
;
Naoki Mori
;
Kazuhiro
Irie
;
Masaya Nagao
关键词:
PPAR¦Ã
;
peroxisome proliferator-activated receptor
;
6-ODA
;
6-octadecynoic acid
;
9-ODA
;
9-octadecynoic acid
;
15d-PDJ2
;
15-deoxy-¦¤12
;
14-prostaglandin J2
刊名:Biochemical and Biophysical Research Communications
出版年:2013
2.
Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin-proteasome system and autophagy
作者:
Kohta Ohnishi
;
Erina Nakahata
;
Kazuhiro
Irie
;
Akira Murakami
;
cancer@kais.kyoto-u.ac.jp
关键词:
CHIP
;
carboxy terminus of Hsc70 interacting protein
;
D3T
;
3H-1
;
2-dithiole-3-thione
;
HNE
;
4-hydroxy-2-nonenal
;
HSP
;
heat shock protein
;
HUM
;
¦Á-humulene
;
Keap1
;
Kelch-like ECH-associated protein 1
;
LC3
;
microtubule-associated protein 1 light-chain 3
;
LPS
刊名:Biochemical and Biophysical Research Communications
出版年:2013
3.
Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities
作者:
Ryo C. Yanagita
;
Hiroaki Kamachi
;
Masayuki Kikumori
;
Harukuni Tokuda
;
Nobutaka Suzuki
;
Kiyotake Suenaga
;
Hiroshi Nagai
;
Kazuhiro
Irie
关键词:
Aplysiatoxin
;
Debromoaplysiatoxin
;
Protein kinase C
;
Tumor promotion
;
Cancer
;
Anti-proliferative activity
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
4.
Structure-activity studies at position 27 of aplog-1, a simplified analog of debromoaplysiatoxin with anti-proliferative activity
作者:
Yusuke Hanaki
;
Masayuki Kikumori
;
Sayo Ueno
;
Harukuni Tokuda
;
Nobutaka Suzuki
;
Kazuhiro
Irie
关键词:
Protein kinase C
;
Tumor-promoter
;
Aplysiatoxin
;
Anti-proliferative
刊名:Tetrahedron
出版年:2013
5.
Non-toxic conformer of amyloid ¦Â may suppress amyloid ¦Â-induced toxicity in rat primary neurons: Implications for a novel therapeutic strategy for Alzheimer¡¯s disease
作者:
Naotaka Izuo
;
Kazuma Murakami
;
Mizuho Sato
;
Mami Iwasaki
;
Yasuhiko Izumi
;
Takahiko Shimizu
;
Akinori Akaike
;
Kazuhiro
Irie
;
Toshiaki Kume
关键词:
AD
;
Alzheimer&rsquo
;
s disease
;
A¦Â40
;
40-mer amyloid ¦Â-protein
;
A¦Â42
;
42-mer amyloid ¦Â-protein
;
DIV
;
days in vitro
;
IgG
;
immunoglobulin G
;
iPSCs
;
induced pluripotent stem cells
;
MTT
;
3-(4
;
5-di-methylthiazol-2-yl)-2
;
5-diphenyltetrazolium bromide
;
NMR
;
n
刊名:Biochemical and Biophysical Research Communications
出版年:2013
6.
Modeling Alzheimer¡¯s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular A¦Â and Differential Drug Responsiveness
作者:
Takayuki Kondo
1
;
2
;
7
;
Masashi Asai
7
;
9
;
10
;
Kayoko Tsukita
1
;
7
;
Yumiko Kutoku
11
;
Yutaka Ohsawa
11
;
Yoshihide Sunada
11
;
Keiko Imamura
1
;
Naohiro Egawa
1
;
Naoki Yahata
1
;
7
;
Keisuke Okita
1
;
Kazutoshi Takahashi
1
;
Isao Asaka
1
;
Takashi Aoi
1
;
Akira Watanabe
1
;
Kaori Watanabe
7
;
10
;
Chie Kadoya
7
;
10
;
Rie Nakano
7
;
10
;
Dai Watanabe
3
;
Kei Maruyama
9
;
Osamu Hori
12
;
Satoshi Hibino
13
;
Tominari Choshi
13
;
Tatsutoshi Nakahata
1
;
Hiroyuki Hioki
4
;
Takeshi Kaneko
4
;
Motoko Naitoh
5
;
Katsuhiro Yoshikawa
5
;
Satoko Yamawaki
5
;
Shigehiko Suzuki
5
;
Ryuji Hata
14
;
Shu-ichi Ueno
15
;
Tsuneyoshi Seki
16
;
Kazuhiro
Kobayashi
16
;
Tatsushi Toda
16
;
Kazuma Murakami
6
;
Kazuhiro
Irie
6
;
William L. Klein
17
;
Hiroshi Mori
18
;
Takashi Asada
19
;
Ryosuke Takahashi
2
;
Nobuhisa Iwata
7
;
10
;
iwata-n@nagasaki-u.ac.jp
;
Shinya Yamanaka
1
;
8
;
Haruhisa Inoue
1
;
7
;
8
;
haruhisa@cira.kyoto-u.ac.jp
刊名:Cell Stem Cell
出版年:2013
7.
Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors
作者:
Takashi Chiba
;
Jun Ohwada
;
Hiroshi Sakamoto
;
Takamitsu Kobayashi
;
Takaaki A. Fukami
;
Machiko
Irie
;
Takaaki Miura
;
Kazuhiro
Ohara
;
Hiroshi Koyano
;
koyanohrs@chugai-pharm.co.jp
关键词:
Glyoxalase I (GLO1)
;
Structure-based drug design (SBDD)
;
N-Hydroxypyridone
;
7-Azaindole
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
8.
Protective effects of caffeoylquinic acids on the aggregation and neurotoxicity of the 42-residue amyloid ¦Â-protein
作者:
Yusaku Miyamae
;
Manami Kurisu
;
Kazuma Murakami
;
Junkyu Han
;
Hiroko Isoda
;
Kazuhiro
Irie
;
Hideyuki Shigemori
关键词:
Alzheimer&rsquo
;
s disease
;
Amyloid ¦Â aggregation
;
Neuroprotective effect
;
Caffeoylquinic acid
;
Structure&ndash
;
activity relationship
刊名:Bioorganic and Medicinal Chemistry
出版年:2012
9.
Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)
作者:
Yasuhiko Izumi
;
Atsuko Matsumura
;
Seiko Wakita
;
Ken-ichi Akagi
;
Hiroyuki Fukuda
;
Toshiaki Kume
;
Kazuhiro
Irie
;
Yuki Takada-Takatori
;
Hachiro Sugimoto
;
Tadashi Hashimoto
;
Akinori Akaike
关键词:
ARE
;
Antioxidant response element
;
DCF
;
2&prime
;
7&prime
;
-dichlorofluorescein
;
DDC
;
2&prime
;
3&prime
;
-dihydroxy-4&prime
;
6&prime
;
-dimethoxychalcone
;
DHE
;
Dihydroethidium
;
DMSO
;
Dimethyl sulfoxide
;
EI
;
Electron impact
;
ETH
;
Ethidium
;
¦Ã&ndash
;
GCS
;
?
刊名:Free Radical Biology and Medicine
出版年:2012
10.
Cytoplasmic SOD Deficiency Promotes the Formation of Amyloid Beta Oligomer and Memory Impairment in a Mouse Model of Alzheimer¡¯s Disease
作者:
Takahiko Shimizu
1
;
2
;
Kazuma Murakami
2
;
3
;
Hiroyuki Hatsuta
2
;
Shigeo Murayama
2
;
Kazuhiro
Irie
3
;
Takuji Shirasawa
4
刊名:Free Radical Biology and Medicine
出版年:2012
1
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