设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
CNKI学位论文(3)
知网期刊论文(4)
在“
Elsevier电子期刊
”中,
命中:
8
条,耗时:0.0249766 秒
在所有数据库中总计命中:
7
条
1.
Inhibition of norovirus 3CL protease by bisulfite adducts of transition state
inhibitor
s
作者:
Sivakoteswara Rao Mandadapu
a
;
&dagger
;
;
Mallikarjuna Reddy Gunnam
a
;
&dagger
;
;
Kok-Chuan Tiew
a
;
Roxanne Adeline Z. Uy
a
;
Allan M. Prior
b
;
Kevin R. Alliston
a
;
Duy H. Hua
b
;
Yunjeong Kim
c
;
Kyeong-Ok Chang
c
;
William C. Groutas
a
;
bill.groutas@wichita.edu
关键词:
Norovirus 3CL protease
;
Bisulfite salt adducts
;
Transition state
inhibitor
s
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Inhibitor
s of proteases and amide hydrolases that employ an α-
ketoheterocycle
as a key enabling functionality
作者:
Bruce E. Maryanoff
;
Michael J. Costanzo
关键词:
Protease
;
Hydrolase
;
Peptidase
;
Inhibitor
;
Structure-based drug design
;
Ketoheterocycle
;
Transition-state analogue
刊名:Bioorganic and Medicinal Chemistry
出版年:2008
3.
Discovery of
inhibitor
s of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design
作者:
David C. Tully
;
Agnè
;
s Vidal
;
Arnab K. Chatterjee
;
Jennifer A. Williams
;
Michael J. Roberts
;
H. Michael Petrassi
;
Glen Spraggon
;
Badry Bursulaya
;
Reyn
;
Pacoma
;
Aaron Shipway
;
Andrew M. Schumacher
;
Henry Danahay
;
Jennifer L. Harris
关键词:
Prostasin
;
PRSS8
;
hCAP
;
Channel-activating protease
;
ENaC activation
;
Peptidomimetic
;
Ketoheterocycle
inhibitor
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
4.
Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse
作者:
J.A. Palmer
;
E.S. Higuera
;
L. Chang
;
S.R. Chaplan
关键词:
fatty acid amide hydrolase
;
FAAH
;
endocannabinoid
;
allodynia
;
nociception
;
thermal injury
刊名:Neuroscience
出版年:2008
5.
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase
inhibitor
s
作者:
James T. Palmer
;
Robert M. Rydzewski
;
Rohan V. Mendonca
;
David Sperandio
;
Jeffrey R. Spencer
;
Bernard L. Hirschbein
;
Julia Lohman
;
Jeri Beltman
;
Margaret Nguyen and Liang Liu
关键词:
Tryptase
;
Serine protease
;
Inhibitor
;
Heterocycle
;
Ketoheterocycle
;
Selective
;
Scaleable process
;
Pharmacokinetics
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2006
6.
Keto-1,3,4-oxadiazoles as cathepsin K
inhibitor
s
作者:
James T. Palmer
;
Bernard L. Hirschbein
;
Harry Cheung
;
John McCarter
;
James W. Janc
;
Z. Walter Yu and Gregg Wesolowski
关键词:
Osteoporosis
;
Cathepsin
;
Cysteine protease
;
Inhibitor
;
Ketoheterocycle
;
Reversible
;
Selective
;
Potent
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2006
7.
C3 activation is inhibited by analogs of compstatin but not by serine protease
inhibitor
s or peptidyl α-
ketoheterocycle
s
作者:
Furlong
;
Stephen T.
;
Dutta
;
Anand S.
;
Coath
;
Matthew M.
;
Gormley
;
James J.
;
Hubbs
;
Stephen J.
;
et. al.
关键词:
Complement
;
Compstatin
;
C3 convertase
;
C3
;
AMC
;
aminomethylcoumarin
;
ANS
;
8-anilino-1-sulphonate
;
BQRA
;
Bodipy quench release assay
;
EIA
;
enzyme linked immunoassay
;
CVFBb
;
Cobra venom factor C3 convertase
;
Em
;
Emission wavelength
;
Ex
;
Excitation wavelengt
刊名:Immunopharmacology
出版年:2000
8.
Design, synthesis, and evaluation of α-
ketoheterocycle
s as class C β-lactamase
inhibitor
s
作者:
Kumar
;
Sanjai
;
Pearson
;
Andre L.
;
Pratt
;
R.F.
刊名:Bioorganic and Medicinal Chemistry
出版年:2001
1
按检索点细分(8)
关键词(4)
文摘(5)
按出版年细分(8)
2013年(1)
2008年(3)
2006年(2)
2001年(1)
2000年(1)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.