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内部出版物
在“
Elsevier电子期刊
”中,
命中:
10
条,耗时:小于0.01 秒
1.
Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECTION): a multicentre, randomised, double-blind extension trial
作者:
Prof Gavin Giovannoni
;
PhD
a
;
g.giovannoni@qmul.ac.uk" class="auth_mail
;
Prof Ralf Gold
;
MD
b
;
Prof Krzysztof Selmaj
;
MD
c
;
Prof Eva Havrdova
;
MD
d
;
Prof Xavier Montalban
;
MD
e
;
Prof Ernst-Wilhelm Radue
;
MD
f
;
Dusan Stefoski
;
MD
g
;
Manjit McNeill
;
MSc
h
;
Lakshmi
Amaravadi
;
PhD
h
;
Marianne Sweetser
;
MD
h
;
Jacob Elkins
;
MD
h
;
Gilmore O'Neill
;
MRCPI
h
;
for the SELECTION Study Investigators &dagger
刊名:Lancet Neurology
出版年:May, 2014
2.
Novel data analysis methods to overcome cut point challenges and enable comprehensive assessment of antidrug binding activity in confirmatory assays
作者:
Alvydas Mikulskis
;
Alvydas.Mikulskis@biogenidec.com
;
Dave Yeung
;
Weiping Chen
;
Devangi Mehta
;
Lakshmi
Amaravadi
关键词:
Confirmatory method
;
Confirmation method
;
Immunogenicity
;
Antidrug antibody
;
Anti-therapeutic antibody
;
Cut point
刊名:Journal of Immunological Methods
出版年:2013
3.
Adapting dried blood spot sampling for an anti-therapeutic antibody immunogenicity assay
作者:
Yuhong Xiang
;
Mackenzie Welch
;
Lakshmi
Amaravadi
;
Christopher Stebbins
;
chris.stebbins@biogenidec.com
关键词:
Dried blood spot
;
Anti-drug antibody
;
Immunogenicity
;
Design of experiment
刊名:Journal of Immunological Methods
出版年:2013
4.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Anti-TWEAK Monoclonal Antibody in Patients With Rheumatoid Arthritis
作者:
Nicolas Wisniacki
;
Lakshmi
Amaravadi
;
Gerald R. Galluppi
;
Timothy S. Zheng
;
Ray Zhang
;
Jessica Kong
;
Linda C. Burkly
关键词:
Fn14
;
pharmacodynamics
;
pharmacokinetics
;
TWEAK
刊名:Clinical Therapeutics
出版年:2013
5.
A novel gamma-fitting statistical method for anti-drug antibody assays to establish assay cut points for data with non-normal distribution
作者:
Brian Schlain
;
Lakshmi
Amaravadi
;
Jean Donley
;
An
;
a Wickramasekera
;
Donald Bennett
;
Meena Subramanyam
关键词:
Immunogenicity
;
ADA assays
;
Cut point
;
Nonparametric
;
Gamma distribution
;
Screening assay
刊名:Journal of Immunological Methods
出版年:2010
6.
Immunogenicity of biologically-derived therapeutics: Assessment and interpretation of nonclinical safety studies
作者:
Rafael Ponce
;
Leslie Abad
;
Lakshmi
Amaravadi
;
Thomas Gelzleichter
;
Elizabeth Gore
;
James Green
;
Shalini Gupta
;
Danuta Herzyk
;
Christopher Hurst
;
Inge A. Ivens
;
Thomas Kawabata
;
Curtis Maier
;
Barbara M
关键词:
Nonclinical safety
;
Immunogenicity
;
Recombinant protein
刊名:Regulatory Toxicology and Pharmacology
出版年:2009
7.
Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products
作者:
Gopi Shankar
;
Viswanath Devanarayan
;
Lakshmi
Amaravadi
;
Yu Chen Barrett
;
Ronald Bowsher
;
Deborah Finco-Kent
;
Michele Fiscella
;
Boris Gorovits
;
Susan Kirschner
;
Michael Moxness
;
Thomas Parish
;
Valerie
关键词:
Method validation
;
Immunogenicity
;
Immunoassay
;
Anti-drug antibody
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2008
8.
Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury
作者:
Soriano
;
Sulpicio G.
;
Amaravadi
;
Lakshmi
S.
;
Wang
;
Yanming F.
;
Zhou
;
Hong
;
Yu
;
Gary X.
;
Tonra
;
James R.
;
et. al.
关键词:
Adhesion molecules
;
Cerebral ischemia
;
Fractalkine
;
Stroke
刊名:Journal of Neuroimmunology
出版年:2002
9.
Functional and structural diversity of the human Dickkopf gene family
作者:
Krupnik
;
Valery E.
;
Sharp
;
John D.
;
Jiang
;
Chian
;
Robison
;
Keith
;
Chickering
;
Troy W.
;
Amaravadi
;
Lakshmi
;
et. al.
关键词:
Antagonist
;
Frizzled related protein
;
In situ hybridization
;
Secreted protein
;
Soggy
;
Wingless
;
Xenopus
;
Cys-1
;
cysteine-rich domain-1
;
Cys-2
;
cysteine-rich domain-2
;
Dkk
;
Dickkopf
;
EST
;
expressed sequence tag
;
FRP
;
Frizzled-related protein
;
ISH
;
in situ
刊名:Gene
出版年:1999
10.
Autonomous Neural Axis Formation by Ectopic Expression of the Protooncogene c-
ski
作者:
Amaravadi
;
Lakshmi
S.
;
Neff
;
Anton W.
;
Sleeman
;
Jonathan P.
;
Smith
;
Rosamund C.
刊名:Developmental Biology
出版年:1997
1
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