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内部出版物
在“
Elsevier电子期刊
”中,
命中:
18
条,耗时:小于0.01 秒
1.
316 - Phenotypic human primary cell-based tumor microenvironment models for evaluation of drug combinations for immune oncology
作者:
A. Baumann
;
J. Ptacek
;
K. Matta
;
J. Melrose
;
M.
Liimatta
;
H. Cho
;
D. Nguyen
;
E. Berg
;
A. O'Mahony
刊名:European Journal of Cancer
出版年:2016
2.
P-340: Effects of preventive home visits on older people's use and costs of health care services: A systematic review
作者:
H.
Liimatta
1
;
P. Lampela
2
;
P. Laitinen-Parkkonen
3
刊名:European Geriatric Medicine
出版年:2015
3.
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors
作者:
Richard M. Pastor
;
pastor.richard@gene.com" class="auth_mail
;
Jason D. Burch
;
Steven Magnuson
;
Daniel F. Ortwine
;
Yuan Chen
;
Kelly De La Torre
;
Xiao Ding
;
Charles Eigenbrot
;
Adam Johnson
;
Marya
Liimatta
;
Yichin Liu
;
Steven Shia
;
Xiaolu Wang
;
Lawren C. Wu
;
Zhonghua Pei
关键词:
SBDD
;
ITK
;
Indazole
;
X-ray crystallography
;
蟺-stacking
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 June 2014
4.
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)
作者:
Colin H. MacKinnon
;
Kevin Lau
;
Jason D. Burch
;
Yuan Chen
;
Jonathon Dines
;
Xiao Ding
;
Charles Eigenbrot
;
Alex
;
er Heifetz
;
Allan Jaochico
;
Adam Johnson
;
Joachim Kraemer
;
Susanne Kruger
;
Thomas M. Kr眉lle
;
Marya
Liimatta
;
Justin Ly
;
Rosemary Maghames
;
Christian A.G.N. Montalbetti
;
Daniel F. Ortwine
;
Yol
;
a P茅rez-Fuertes
;
Steven Shia
;
et al.
关键词:
ITK inhibitor
;
TCR signalling
;
Benzothiazole
;
Anti-inflammatory
;
Asthma
;
SAR
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 December, 2013
5.
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors
作者:
Sharada Labadie
;
Kathy Barrett
;
Wade S. Blair
;
Christine Chang
;
Gauri Deshmukh
;
Charles Eigenbrot
;
Paul Gibbons
;
Adam Johnson
;
Jane R. Kenny
;
Pawan Bir Kohli
;
Marya
Liimatta
;
Patrick J. Lupardus
;
Steven Shia
;
Micah Steffek
;
Savita Ubhayakar
;
Anne van Abbema
;
Mark Zak
关键词:
JAK inhibitors
;
8-Oxo-pyridopyrimidines
;
Rheumatoid arthritis
;
Hematopoiesis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
6.
Lead identification of novel and selective TYK2 inhibitors
作者:
Jun Liang
;
Vickie Tsui
;
Anne Van Abbema
;
Liang Bao
;
Kathy Barrett
;
Maureen Beresini
;
Leo Berezhkovskiy
;
Wade S. Blair
;
Christine Chang
;
James Driscoll
;
Charles Eigenbrot
;
Nico Ghilardi
;
Paul Gibbons
;
Jason Halladay
;
Adam Johnson
;
Pawan Bir Kohli
;
Yingjie Lai
;
Marya
Liimatta
;
Priscilla Mantik
;
Kapil Menghrajani
;
et al.
关键词:
Kinase inhibitor
;
Janus family kinase
;
Structure&ndash
;
activity relationship
;
Crystal structure
;
Hit to lead
;
Immunology
刊名:European Journal of Medicinal Chemistry
出版年:2013
7.
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc
作者:
Benjamin P. Fauber
;
Gladys de Leon Boenig
;
Brenda Burton
;
C茅line Eidenschenk
;
Christine Everett
;
Alberto Gobbi
;
Sarah G. Hymowitz
;
Adam R. Johnson
;
Marya
Liimatta
;
Peter Lockey
;
Maxine Norman
;
Wenjun Ouyang
;
Olivier Ren茅
;
Harvey Wong
关键词:
RORc
;
ROR纬
;
T0901317
;
X-ray structure
;
IL-17
;
Inflammation
;
Autoimmune
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 December, 2013
8.
Superoxide production during ischemia-reperfusion in the perfused rat heart: A comparison of two methods of measurement
作者:
Juha P. Nä
;
pä
;
nkangas
a
;
Erkki V.
Liimatta
b
;
Pä
;
ivi Joensuu
c
;
Ulrich Bergmann
d
;
Kari Ylitalo
e
;
Ilmo E. Hassinen
b
;
ilmo.hassinen@oulu.fi
关键词:
Ischemia
;
Reperfusion
;
Superoxide
;
Lucigenin
;
Dihydroethidine
刊名:Journal of Molecular and Cellular Cardiology
出版年:2012
9.
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)
作者:
Douglas S. Johnson
;
Kay Ahn
;
Suzanne Kesten
;
Scott E. Lazerwith
;
Yuntao Song
;
Mark Morris
;
Lorraine Fay
;
Tracy Gregory
;
Cory Stiff
;
James B. Dunbar Jr.
;
Marya
Liimatta
;
David Beidler
;
Sarah Smith
;
Tyz
关键词:
FAAH inhibitor
;
Fatty acid amide hydrolase
;
Urea
;
Activity-based protein profiling
;
Covalent inhibitor
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
10.
Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain
作者:
Kay Ahn
;
Douglas S. Johnson
;
Mauro Mileni
;
David Beidler
;
Jonathan Z. Long
;
Michele K. McKinney
;
Eranthie Weerapana
;
Nalini Sadagopan
;
Marya
Liimatta
;
Sarah E. Smith
;
Scott Lazerwith
;
Cory Stiff
;
Satw
刊名:Chemistry & Biology
出版年:2009
1
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