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CNKI学位论文(14)
知网期刊论文(9)
在“
Elsevier电子期刊
”中,
命中:
26
条,耗时:小于0.01 秒
在所有数据库中总计命中:
23
条
1.
Systems toxicology-based assessment of the candidate modified risk tobacco product THS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells
作者:
Carine Poussin
;
Carine.Poussin@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Alexandra Laurent
;
Manuel
C.
Peitsch
;
Julia Hoeng
;
Hector De Leon
关键词:
CS
;
cigarette smoke
;
FDR
;
false discovery rate
;
HCAECs
;
human coronary artery endothelial cells
;
I
;
D
;
and FD
;
indirect
;
direct and fresh direct
;
respectively
;
ICAM-1
;
intercellular adhesion molecule 1
;
MM6
;
Mono Mac 6
;
MRTP
;
modified risk tobacco product
;
NPA
;
network perturbation amplitude
;
(R)BIF
;
(Relative) biological impact factor
;
SELE
;
E-selectin
;
SM
;
starvation medium
;
TACE
;
tumor necrosis factor-α-converting enzyme
;
THS2.2
;
Tobacco Heating System 2.2
;
TNFα
;
tumor necrosis factor-alpha
刊名:Toxicology
出版年:2016
2.
Evaluation of the tobacco heating system 2.2. Part 9: Application of systems pharmacology to identify exposure response markers in peripheral blood of smokers switching to THS2.2
作者:
Florian Martin
;
Marja Talikka
;
Nikolai V. Ivanov
;
Christelle Haziza
;
Julia Hoeng
;
Hoeng@pmi.com
;
Manuel
C.
Peitsch
关键词:
Smoking
;
Blood
;
Exposure response
;
Gene expression signature
;
Novel tobacco heating system
;
MRTP
刊名:Regulatory Toxicology and Pharmacology
出版年:2016
3.
Evaluation of the Tobacco Heating System 2.2. Part 1: Description of the system and the scientific assessment program
作者:
Maurice R. Smith
;
Maurice.Smith@pmi.com
;
Bruce Clark
;
Frank Lü
;
dicke
;
Jean-Pierre Schaller
;
Patrick Vanscheeuwijck
;
Julia Hoeng
;
Manuel
C.
Peitsch
关键词:
Tobacco harm reduction
;
Heat-not-burn
;
Modified risk tobacco product
;
Scientific assessment approach
刊名:Regulatory Toxicology and Pharmacology
出版年:2016
4.
Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects
作者:
Bjoern Titz
;
1
;
bjorn.titz@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Alain Sewer
1
;
Thomas Schneider
1
;
Ashraf Elamin
1
;
Florian Martin
1
;
Sophie Dijon
;
Karsta Luettich
;
Em
manuel
Guedj
;
Gregory Vuillaume
;
Nikolai V. Ivanov
;
Michael J. Peck
;
Nveed I. Chaudhary
;
Julia Hoeng
;
Manuel
C.
Peitsch
关键词:
COPD
;
Smoking
;
Sputum
;
Systems toxicology
;
Quantitative proteomics
刊名:Journal of Proteomics
出版年:2015
5.
Aerosol from a candidate modified risk tobacco product has reduced effects on chemotaxis and transendothelial migration compared to combustion of conventional cigarettes
作者:
Marco van der Toorn
;
1
;
Marco.vanderToorn@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Stefan Frentzel
1
;
Stefan.Frentzel@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Hector De Leon
hdeleon68@hotmail.com" class="auth_mail" title="E-mail the corresponding author
;
Didier Goedertier
Didier.Goedertier@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Manuel
C.
Peitsch
Manuel.Peitsch@pmi.com" class="auth_mail" title="E-mail the corresponding author
;
Julia Hoeng
Julia.Hoeng@pmi.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Transendothelial migration
;
THP-1 cells
;
Endothelial cells
;
Atherosclerosis
;
Modified risk tobacco product
;
Tobacco-heating system
刊名:Food and Chemical Toxicology
出版年:2015
6.
A decade of Systems Biology: where are we and where are we going to?
作者:
Manuel
C.
Peitsch
manuel
.
peitsch
@pmi.com" class="auth_mail
刊名:Drug Discovery Today
出版年:February, 2014
7.
Quantitative assessment of biological impact using transcriptomic data and mechanistic network models
作者:
Ty M. Thomson
;
Alain Sewer
;
Florian Martin
;
Vincenzo Belcastro
;
Brian P. Frushour
;
Stephan Gebel
;
Jennifer Park
;
Walter K. Schlage
;
Marja Talikka
;
Dmitry M. Vasilyev
;
Jurjen W. Westra
;
Julia Hoeng
;
Manuel
C.
Peitsch
关键词:
Quantification
;
Biological impact
;
Bioactive substance
;
Transcriptome
;
Network model
;
Mechanisms
刊名:Toxicology and Applied Pharmacology
出版年:2013
8.
Cigarette smoke induces molecular responses in respiratory tissues of ApoE
鈭?鈭?/sup> mice that are progressively deactivated upon cessation
作者:
St茅phanie Bou茅
;
H茅ctor De Le贸n
;
Walter K. Schlage
;
Michael J. Peck
;
Horst Weiler
;
An Berges
;
Gr茅gory Vuillaume
;
Florian Martin
;
Baerbel Friedrichs
;
Stefan Lebrun
;
Kris Meurrens
;
Nadine Schracke
;
Michaela Moehring
;
Yvonne Steffen
;
Jutta Schueller
;
Patrick Vanscheeuwijck
;
Manuel
C.
Peitsch
;
Julia Hoeng
关键词:
BALF
;
Inflammation
;
ApoE&minus
;
/&minus
;
mice
;
Smoking
;
Smoking cessation
;
Genome-wide expression
刊名:Toxicology
出版年:6 December, 2013
9.
Systems biology approach reveals a dose-dependent recovery of primary human airway epithelium culture after exposure to cigarette smoke
作者:
Carole Mathis
;
Stephan Gebel
;
Carine Poussin
;
Arnd Hengstermann
;
Dirk Weisensee
;
Alain Sewer
;
Vincenzo Belcastro
;
Sam Ansari
;
S
;
ra Wagner
;
Julia Hoeng
;
Manuel
C.
Peitsch
刊名:Toxicology Letters
出版年:2013
10.
Systems-toxicology approach to evaluate the biological impact of a subset of harmful/potentially harmful constituents of tobacco smoke
作者:
Ignacio Gonzalez-Suarez
;
Carole Mathis
;
Em
manuel
Guedj
;
Paul Walker
;
Samantha Ellis
;
Heather Woodhouse
;
Remi Dulize
;
S
;
ra Wagner
;
Florian Martin
;
Nikolai Ivanov
;
Julia Hoeng
;
Manuel
C.
Peitsch
刊名:Toxicology Letters
出版年:2013
1
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