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在“Elsevier电子期刊”中，命中：21条，耗时：小于0.01 秒

在所有数据库中总计命中：16条

1.MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

作者：Jon Kerry¹ ; Laura Godfrey¹ ; Emmanouela Repapi² ; Marta Tapia¹ ; Neil P. Blackledge³ ; Helen Ma⁴ ; Erica Ballabio¹ ; Sorcha O&rsquo ; Byrne⁵ ; Frida Ponthan⁶ ; Olaf Heidenreich⁶ ; Anindita Roy⁵ ; Irene Roberts¹ ; ⁵ ; Marina Konopleva⁴ ; Robert J. Klose³ ; Huimin Geng⁷ ; Thomas A. Milne¹ ; ⁸ ; ^{thomas.milne@imm.ox.ac.uk}

关键词：MLL ; MLL-AF4 ; DOT1L ; H3K79me2 ; leukemia ; epigenetic therapy ; drug combination therapy ; epigenetic spreading

刊名：Cell Reports

出版年：2017

2.Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia

作者：Ilaria Iacobucci¹ ; ¹⁹ ; Yongjin Li² ; ¹⁹ ; Kathryn G. Roberts¹ ; Stephanie M. Dobson³ ; Jaeseung C. Kim⁴ ; ⁵ ; Debbie Payne-Turner¹ ; Richard C. Harvey⁶ ; Marcus Valentine⁷ ; Kelly McCastlain¹ ; John Easton² ; Donald Yergeau² ; Laura J. Janke¹ ; Ying Shao¹ ; ² ; I-Ming L. Chen⁶ ; Michael Rusch² ; Sasan Zandi³ ; Steven M. Kornblau⁸ ; Marina Konopleva⁸ ; Elias Jabbour⁸ ; Elisabeth M. Paietta⁹ ; Jacob M. Rowe¹⁰ ; Ching-Hon Pui¹¹ ; Julie Gastier-Foster¹² ; Zhaohui Gu¹ ; Shalini Reshmi¹² ; Mignon L. Loh¹³ ; Janis Racevskis⁸ ; Martin S. Tallman¹⁴ ; Peter H. Wiernik¹⁵ ; Mark R. Litzow¹⁶ ; Cheryl L. Willman⁶ ; John D. McPherson¹⁷ ; James R. Downing¹ ; Jinghui Zhang² ; John E. Dick³ ; Stephen P. Hunger¹⁸ ; Charles G. Mullighan¹ ; ^{charles.mullighan@stjude.org" class="auth_mail" title="E-mail the corresponding author}

刊名：Cancer Cell

出版年：2016

3.MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

作者：Juliana M. Benito¹ ; Laura Godfrey² ; Kensuke Kojima³ ; Leah Hogdal⁴ ; Mark Wunderlich⁵ ; Huimin Geng⁶ ; Isabel Marzo⁷ ; Karine G. Harutyunyan¹ ; Leonard Golfman⁸ ; Phillip North² ; Jon Kerry² ; Erica Ballabio² ; Triona Ní ; Chonghaile⁹ ; Oscar Gonzalo⁷ ; Yihua Qiu¹ ; Irmela Jeremias¹⁰ ; LaKiesha Debose¹ ; Eric O&rsquo ; Brien⁵ ; Helen Ma¹ ; Ping Zhou¹ ; Rodrigo Jacamo¹ ; Eugene Park⁶ ; Kevin R. Coombes¹¹ ; Nianxiang Zhang¹¹ ; Deborah A. Thomas¹ ; Susan O&rsquo ; Brien¹ ; Hagop M. Kantarjian¹ ; Joel D. Leverson¹² ; Steven M. Kornblau¹ ; Michael Andreeff¹ ; Markus Mü ; schen⁶ ; Patrick A. Zweidler-McKay⁸ ; James C. Mulloy⁵ ; Anthony Letai⁴ ; Thomas A. Milne² ; ^{thomas.milne@imm.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Marina Konopleva¹ ; ^{mkonople@mdanderson.org" class="auth_mail" title="E-mail the corresponding author}

关键词：apoptosis pathways ; leukemias ; bcl-2 family members ; MLL/AF4 ; DOT1L ; H3K79 methylation

刊名：Cell Reports

出版年：2015

4.Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study

作者：Dr Elias Jabbour ; MD^a ; ^{ejabbour@mdanderson.org" class="auth_mail" title="E-mail the corresponding author} ; Prof Hagop Kantarjian ; MD^a ; Prof Farhad Ravandi ; MD^a ; Prof Deborah Thomas ; MD^a ; Prof Xuelin Huang ; PhD^b ; Prof Stefan Faderl ; MD^a ; Prof Naveen Pemmaraju ; MD^a ; Naval Daver ; MD^a ; Prof Guillermo Garcia-Manero ; MD^a ; Koji Sasaki ; MD^a ; Prof Jorge Cortes ; MD^a ; Rebecca Garris^a ; C Cameron Yin ; MD^c ; Joseph D Khoury ; MD^c ; Prof Jeffrey Jorgensen ; MD^b ; Prof Zeev Estrov ; MD^a ; Zachary Bohannan ; MA^a ; Marina Konopleva ; MD^a ; Tapan Kadia ; MD^a ; Nitin Jain ; MD^a ; Courtney DiNardo ; MD^a ; Prof William Wierda ; MD^a ; Vicky Jeanis ; RN^a ; Prof Susan O'Brien ; MD^a

刊名：The Lancet Oncology

出版年：2015

5.A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells

作者：Stephen M.F. Jamieson ; Yongchuan Gu ; Donya Moradi Manesh ; Jad El-Hoss ; Duohui Jing ; Karen L. MacKenzie ; Christopher P. Guise ; Annika Foehrenbacher ; Susan M. Pullen ; Juliana Benito ; Jeffrey B. Smaill ; Adam V. Patterson ; Medhanie A. Mulaw ; Marina Konopleva ; Stefan K. Bohl ; er ; Richard B. Lock ; William R. Wilson

关键词：Aldo-keto reductase 1C3 ; Leukaemia ; PR-104 ; SN34037 ; Fluorogenic assays

刊名：Biochemical Pharmacology

出版年：1 March, 2014

6.Modest activity of pomalidomide in patients with myelofibrosis and significant anemia

作者：Naval Daver ; Aditi Shastri ; Tapan Kadia ; Alfonso Quintas-Cardama ; Elias Jabbour ; Marina Konopleva ; Susan O鈥橞rien ; Sherry Pierce ; Lingsha Zhou ; Jorge Cortes ; Hagop Kantarjian ; Srdan Verstovsek

关键词：Pomalidomide ; Myelofibrosis ; Anemia

刊名：Leukemia Research

出版年：November, 2013

7.CXC Chemokine Receptor 4 Expression, CXC Chemokine Receptor 4 Activation, and Wild-Type Nucleophosmin Are Independently Associated With Unfavorable Prognosis in Patients With Acute Myeloid Leukemia

作者：Sergej Konoplev ; Pei Lin ; C. Cameron Yin ; E. Lin ; Graciela M. Nogueras Gonz谩lez ; Hagop M. Kantarjian ; Michael Andreeff ; L. Jeffrey Medeiros ; Marina Konopleva

关键词：Acute myeloid leukemia ; AML ; CXCR4 ; CXCR4 activation ; CXCR4 phosphorylation ; NPM1 ; Prognosis

刊名：Clinical Lymphoma Myeloma and Leukemia

出版年：December, 2013

8.Outcome After Failure of Second Generation Tyrosine Kinase Inhibitors Treatment As First-line Therapy for Patients With Chronic Myeloid Leukemia

作者：Alireza Eghtedar ; Hagop Kantarjian ; Elias Jabbour ; Susan O'Brien ; Elizabeth Burton ; Guillermo Garcia-Manero ; Srdan Verstovsek ; Farhad Ravi ; Gautam Borthakur ; Marina Konopleva ; Alfonso Quintas-Cardama ; Jorge Cortes

关键词：Dasatinib ; Nilotinib ; CML ; TKIs ; Discontinuation

刊名：Clinical Lymphoma Myeloma and Leukemia

出版年：2013

9.A Randomized Controlled Trial of an Intensive Insulin Regimen in Patients With Hyperglycemic Acute Lymphoblastic Leukemia

作者：Khanh Vu ; Naifa Busaidy ; Maria E. Cabanillas ; Marina Konopleva ; Stefan Faderl ; Deborah A. Thomas ; Susan O'Brien ; Kristine Broglio ; Joe Ensor ; Carmen Escalante ; Michael Andreeff ; Hagop Kantarjian ; Victor Lavis ; Sai-Ching Jim Yeung

关键词：Diabetes ; Intensive insulin regimen ; Metformin ; Secretagogues ; Thiazolidinediones

刊名：Clinical Lymphoma Myeloma and Leukemia

出版年：2012

10.Twice-Daily Fludarabine and Cytarabine Combination With or Without Gentuzumab Ozogamicin is Effective in Patients With Relapsed/Refractory Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, and Blast- Phase Chronic Myeloid Leukemia

作者：Elias Jabbour ; Guillermo Garcia-Manero ; Jorge Cortes ; Farhad Ravi ; William Plunkett ; Varsha G ; hi ; Stefan Faderl ; Susan O'Brien ; Gautam Borthakur ; Tapan Kadia ; Jan Burger ; Marina Konopleva ; Mark Brt ; Xuelin Huang ; Hagop Kantarjian

关键词：Acute myeloid leukemia ; Efficacy ; Refractory ; Safety

刊名：Clinical Lymphoma Myeloma and Leukemia

出版年：2012

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