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内部出版物
在“
Elsevier电子期刊
”中,
命中:
5
条,耗时:小于0.01 秒
1.
The anesthetized guinea pig: An effective early cardiovascular derisking and lead optimization model
作者:
Pierre Morissette
;
Masahiro Nishida
;
Elena Trepakova
;
John Imredy
;
Arm
;
o Lagrutta
;
Alysia Chaves
;
Kimberly Hoagl
;
Chao-Min Lei Hoe
;
Matthew
M.
Zrada
;
Jeffrey J. Travis
;
Gloria J. Zingaro
;
Pamela Gerenser
;
Greg Friedrichs
;
Joseph J. Salata
关键词:
CVGP
;
anesthetized cardiovascular guinea pig
;
Cu
;
free plasma concentration
;
GP
;
guinea pig
;
hCav1.2
;
human L-type calcium current
;
hERG
;
human ether-a-go-go related gene
;
hNav1.5
;
human cardiac Na
;
+ channel ¦Á-subunit
;
IKr
;
rapidly activating delaye
刊名:Journal of Pharmacological and Toxicological Methods
出版年:2013
2.
A potent and orally active HIV-1 integrase inhibitor
作者:
Melissa S. Egbertson
;
H. Marie Moritz
;
Jeffrey Y. Melamed
;
Wei Han
;
Debra S. Perlow
;
Michelle S. Kuo
;
Mark Embrey
;
Joseph P. Vacca
;
Matthew
M.
Zrada
;
Am
;
a R. Cortes
;
et al.
关键词:
HIV
;
AIDS
;
Integrase
;
Strand transfer
;
1
;
6-Naphthyridine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
3.
Kinesin spindle protein (KSP) inhibitors. Part V: Discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by β-fluorin
作者:
Christopher D. Cox
;
Michael J. Breslin
;
David B. Whitman
;
Paul J. Coleman
;
Robert M. Garbaccio
;
Mark E. Fraley
;
Matthew
M.
Zrada
;
Carolyn A. Buser
;
Eileen S. Walsh
;
Kelly Hamilton
;
et al.
关键词:
Pgp
;
Antimitotics
;
Multidrug-resistance
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
4.
8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors
作者:
Thorsten E. Fisher
;
Boyoung Kim
;
Donnette D. Staas
;
Terry A. Lyle
;
Steven D. Young
;
Joseph P. Vacca
;
Matthew
M.
Zrada
;
Daria J. Hazuda
;
Peter J. Felock
;
William A. Schleif
;
Lori J. Gabryelski
;
M. Reza
关键词:
HIV
;
Integrase inhibitor
;
Antiviral
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
5.
Development of an efficient and selective radioligand for bradykinin B
1
receptor occupancy studies
作者:
Su
;
Dai-Shi
;
Markowitz
;
M. Kristine
;
Murphy
;
Kathy L.
;
Wan
;
Bang-Lin
;
Zrada
;
Matthew
M.
;
Harrell
;
C. Meacham
;
et. al.
关键词:
Bradykinin B
1
receptor
;
Antagonist
;
Radioligand
;
Ex vivo
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2004
1
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