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CNKI学位论文(38)
知网期刊论文(12)
在“
Elsevier电子期刊
”中,
命中:
10
条,耗时:小于0.01 秒
在所有数据库中总计命中:
50
条
1.
Recent progress in the development of small-molecule glucagon receptor antagonists
作者:
Matthew
F.
Sammons
;
Esther C.Y. Lee
关键词:
Glucagon receptor antagonist
;
Glucagon
;
Type-2 diabetes
;
Small molecule antagonists
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2015
2.
Identification of a novel conformationally constrained glucagon receptor antagonist
作者:
Esther C.Y. Lee
;
Meihua Tu
;
Benjamin D. Stevens
;
Jianwei Bian
;
Gary Aspnes
;
Christian Perreault
;
Matthew
F.
Sammons
;
Stephen W. Wright
;
John Litchfield
;
Amit S. Kalgutkar
;
Raman Sharma
;
Mary T. Didiuk
;
David C. Ebner
;
Kevin J. Filipski
;
Janice Brown
;
Karen Atkinson
;
Jeffrey A. Pfefferkorn
;
Angel Guzman-Perez
关键词:
Glucagon receptor antagonist
;
Diabetes mellitus
;
Physicochemical properties
;
Metabolite
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 February, 2014
3.
Modulation of adipose tissue thermogenesis as a method for increasing energy expenditure
作者:
Matthew
F.
Sammons
;
David A. Price
关键词:
Brown adipose tissue
;
Beige adipose
;
Thermogenesis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 January, 2014
4.
The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus
作者:
Angel Guzman-Perez
;
aguzmanp@amgen.com
;
Jeffrey A. Pfefferkorn
;
Esther C.Y. Lee
;
Benjamin D. Stevens
;
Gary E. Aspnes
;
Jianwei Bian
;
Mary T. Didiuk
;
Kevin J. Filipski
;
Dianna Moore
;
Christian Perreault
;
Matthew
F.
Sammons
;
Meihua Tu
;
Janice Brown
;
Karen Atkinson
;
John Litchfield
;
Beijing Tan
;
Brian Samas
;
William J. Zavadoski
;
Christopher T. Salatto
;
Judith Treadway
关键词:
Glucagon receptor antagonist
;
Diabetes mellitus
;
Physicochemical properties
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
5.
Design and synthesis of aryl sulfonamide-based nonsteroidal mineralocorticoid receptor antagonists
作者:
Kentaro Futatsugi
;
David W. Piotrowski
;
Agustin Casimiro-Garcia
;
Shaughn Robinson
;
Matthew
Sammons
;
Paula M. Loria
;
Mary E. Banker
;
Donna N. Petersen
;
Natalia J. Schmidt
关键词:
Mineralocorticoid receptor
;
Nonsteroidal MR antagonist
;
Aryl sulfonamide
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 December, 2013
6.
Corrigendum to ¡°The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus¡± [Bioorg. Med. Chem. Lett. 22 (2012) 7100-7105]
作者:
Jeffrey A. Pfefferkorn
;
Meihua Tu
;
Kevin J. Filipski
;
Angel Guzman-Perez
;
Jianwei Bian
;
Gary E. Aspnes
;
Matthew
F.
Sammons
;
Wei Song
;
Jian-Cheng Li
;
Christopher S. Jones
;
Leena Patel
;
Tim Rasmusson
;
Dongxiang Zeng
;
Kapil Karki
;
Michael Hamilton
;
Richard Hank
;
Karen Atkinson
;
John Litchfield
;
Robert Aiello
;
Levenia Baker
;
et al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
7.
A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity
作者:
Kevin J. Filipski
;
&dagger
;
;
kevin.filipski@pfizer.com
;
Jianwei Bian
;
David C. Ebner
;
Esther C.Y. Lee
;
Jian-Cheng Li
;
Matthew
F.
Sammons
;
Stephen W. Wright
;
Benjamin D. Stevens
;
Mary T. Didiuk
;
Meihua Tu
;
Christian Perreault
;
Janice Brown
;
Karen Atkinson
;
Beijing Tan
;
Christopher T. Salatto
;
John Litchfield
;
Jeffrey A. Pfefferkorn
;
Angel Guzman-Perez
关键词:
Glucagon receptor antagonist
;
Diabetes
;
Pyrazole ether
;
Aminopyrazole
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
8.
Synthesis and cross coupling of a highly substituted 2-pyridylboronate: application to the large scale synthesis of a mineralocorticoid antagonist
作者:
Charles Boos
;
Daniel M. Bowles
;
Cuiman Cai
;
Agustin Casimiro-Garcia
;
Xiangyang Chen
;
Catherine A. Hulford
;
Sandra M. Jennings
;
E. Jason Kiser
;
David W. Piotrowski
;
;
;
david.w.piotrowski@pfizer.com
;
Matthew
Sammons
;
Robert A. Wade
关键词:
Suzuki&ndash
;
Miyaura coupling
;
2-Pyridylboronate
;
Pyrazoline
;
Large-scale synthesis
刊名:Tetrahedron Letters
出版年:2011
9.
Differential Regulation of Unconventional Fission Yeast Myosins via the Actin Track
作者:
Joseph E. Clayton
;
Matthew
R.
Sammons
;
Benjamin C. Stark
;
Alex R. Hodges
;
Matthew
Lord
刊名:Current Biology
出版年:2010
10.
A convenient and rapid approach for the synthesis of 1-benzyl-3-heterocyclic pyrazoles
作者:
Michael P. Curtis
;
Matthew
F.
Sammons
;
David W. Piotrowski
刊名:Tetrahedron Letters
出版年:2009
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