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CNKI学位论文(94)
知网期刊论文(19)
在“
Elsevier电子期刊
”中,
命中:
39
条,耗时:0.0150024 秒
在所有数据库中总计命中:
113
条
1.
In vivo pro
of
-
of
-concept
of
removal
of
the
huntingtin
caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model
of
Huntington’s disease
作者:
Joã
;
o Casaca-Carreira
a
;
b
;
c
;
j.casacacarreira@maastrichtuniversity.nl
;
Lodewijk J.A. Toonen
d
;
Melvin M. Evers
d
;
e
;
Ali Jahanshahi
a
;
b
;
c
;
Willeke M.C. van-Roon-Mom
d
;
Yasin Temel
a
;
b
;
c
;
y.temel@maastrichtuniversity.nl
关键词:
HD
;
Exon skipping
;
Mouse
;
Intracerebroventricular
;
RNA
刊名:Biomedicine & Pharmacotherapy
出版年:2016
2.
Huntingtin
disrupts lipid bilayers in a polyQ-length dependent manner
作者:
Kathleen A. Burke
a
;
Kaitlin M. Hensal
a
;
C. Samuel Umbaugh
a
;
Maxmore Chaibva
a
;
b
;
Justin Legleiter
a
;
b
;
c
;
justin.legleiter@mail.wvu.edu
关键词:
Polyglutamine
;
Huntingtin
;
Huntington's disease
;
Atomic force microscopy
;
Protein aggregation
;
Supported lipid bilayer
刊名:Biochimica et Biophysica Acta (BBA)/Biomembranes
出版年:2013
3.
Slow Amyloid Nucleation via ¦Á-Helix-Rich Oligomeric Intermediates in Short Polyglutamine-Containing
Huntingtin
Fragments
作者:
Murali Jayaraman
1
;
1
;
Ravindra Kodali
1
;
Bankanidhi Sahoo
1
;
Ashwani K. Thakur
1
;
1
;
Anand Mayasundari
2
;
1
;
Rakesh Mishra
1
;
Cynthia B. Peterson
2
;
Ronald Wetzel
1
;
rwetzel@pitt.edu
关键词:
polyQ
;
polyglutamine
;
htt
;
huntingtin
;
AUC
;
analytical ultracentrifugation
;
SEC
;
size-exclusion chromatography
;
PBS
;
phosphate-buffered saline
;
MW
;
molecular weight
;
FTIR
;
Fourier transform infrared
;
EM
;
electron micrograph
;
ThT
;
thi
of
lavin T
;
DLS
;
dynami
刊名:Journal
of
Molecular Biology
出版年:2012
4.
Inhibiting the Nucleation
of
Amyloid Structure in a
Huntingtin
Fragment by Targeting ¦Á-Helix-Rich Oligomeric Intermediates
作者:
Rakesh Mishra
&dagger
;
;
Murali Jayaraman
&dagger
;
;
1
;
Bartholomew P. Roland
;
Elizabeth Landrum
;
Timothy Fullam
;
Ravindra Kodali
;
Ashwani K. Thakur
1
;
Irene Arduini
;
Ronald Wetzel
;
rwetzel@pitt.edu
关键词:
htt
;
huntingtin
;
polyQ
;
polyglutamine
;
HD
;
Huntington's disease
;
SEC
;
size-exclusion chromatography
;
LC
;
liquid chromatography
;
MS
;
mass spectrometry
;
EM
;
electron microscopy
;
FTIR
;
Fourier transform infrared spectroscopy
;
PBS
;
phosphate-buffered saline
刊名:Journal
of
Molecular Biology
出版年:2012
5.
Serine Phosphorylation Suppresses
Huntingtin
Amyloid Accumulation by Altering Protein Aggregation Properties
作者:
Rakesh Mishra
1
;
2
;
Cody L. Hoop
1
;
Ravindra Kodali
1
;
2
;
Bankanidhi Sahoo
1
;
2
;
Patrick C.A. van der Wel
1
;
Ronald Wetzel
1
;
2
;
rwetzel@pitt.edu
关键词:
polyQ
;
polyglutamine
;
HD
;
Huntington's disease
;
ssNMR
;
solid-state NMR
;
WT
;
wild type
;
EM
;
electron microscopy
;
FRET
;
fluorescence resonance energy transfer
;
PBS
;
phosphate-buffered saline
;
FTIR
;
Fourier transform infrared spectroscopy
;
MAS
;
magic angle s
刊名:Journal
of
Molecular Biology
出版年:2012
6.
Huntingtin
with an expanded polyglutamine repeat affects the Jab1-p27(Kip1) pathway
作者:
S.Y. Cong
a
;
b
;
congshuyan@hotmail.com
;
B.A. Pepers
b
;
T.T. Zhou
c
;
H. Kerkdijk
b
;
R.A. Roos
d
;
G.J. van Ommen
b
;
J.C. Dorsman
b
;
e
;
JC.Dorsman@vumc.nl
关键词:
Huntingtin
;
Polyglutamine
;
Jab1
;
p27(Kip1)
;
Transcriptional deregulation
刊名:Neurobiology
of
Disease
出版年:2012
7.
Physical Chemistry
of
Polyglutamine: Intriguing Tales
of
a Monotonous Sequence
作者:
Ronald Wetzel
关键词:
polyQ
;
polyglutamine
;
HD
;
Huntington's disease
;
htt
;
huntingtin
;
FCS
;
fluorescence correlation spectroscopy
;
httNT
;
htt 17-amino acid N-terminus
;
AUC
;
analytical ultracentrifugation
;
GFP
;
green fluorescent protein
;
FTIR
;
Fourier transform infrared spectro
刊名:Journal
of
Molecular Biology
出版年:2012
8.
Light and electron microscopic characterization
of
the evolution
of
cellular pathology in Hdh
Q92
Huntington's disease knock-in mice
作者:
Zubeyde Bayram-Weston
a
;
Bayram-WestonZ@cardiff.ac.uk
;
Lesley Jones
b
;
Stephen B. Dunnett
a
;
Simon P. Brooks
a
关键词:
Huntington's disease
;
Aggregations
;
Inclusions
;
HdhQ92/Q92 knock-in mouse line
;
Electron microscopy
刊名:Brain Research Bulletin
出版年:2012
9.
TR-FRET-Based Duplex Immunoassay Reveals an Inverse Correlation
of
Soluble and Aggregated Mutant
huntingtin
in Huntington's Disease
作者:
Barbara Baldo
1
;
4
;
Paolo Paganetti
1
;
4
;
5
;
Stephan Grueninger
1
;
David Marcellin
1
;
Linda
;
S. Kaltenbach
2
;
Donald
;
C. Lo
2
;
Martin Semmelroth
1
;
Andjelija Zivanovic
1
;
Dorothé
;
e Abramowski
1
;
Donna Smith
3
;
Gregor
;
P. Lotz
1
;
Gillian
;
P. Bates
3
;
Andreas Weiss
1
;
andreas-1.weiss@novartis.com
刊名:Chemistry & Biology
出版年:2012
10.
Small N-
terminal
mutant
huntingtin
fragments
, but not wild type, are mainly present in monomeric form: Implications for pathogenesis
作者:
Shu-Yan Cong
;
Barry A. Pepers
;
Raymund A.C. Roos
;
Gert-Jan B. van Ommen and Josephine C. Dorsman
关键词:
Huntington's disease
;
N-
terminal
fragments
of
huntingtin
;
Native property
;
Molecular pathogenesis
刊名:Experimental Neurology
出版年:2006
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