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在“
Elsevier电子期刊
”中,
命中:
48
条,耗时:小于0.01 秒
1.
APC/C
Fzr/Cdh1
-Dependent Regulation of Planar Cell Polarity Establishment via
Nek2
Kinase Acting on Dishevelled
作者:
Ursula Weber
1
;
Marek Mlodzik
1
;
2
;
marek.mlodzik@mssm.edu
关键词:
anaphase-promoting complex
;
post-mitotic function
;
planar cell polarity
;
Drosophila
;
asymmetric protein localization
;
Nek2
kinase
;
proteasome-mediated degradation
刊名:Developmental Cell
出版年:2017
2.
The APC/C Coordinates Retinal Differentiation with G1 Arrest through the
Nek2
-Dependent Modulation of Wingless Signaling
作者:
Torcato Martins
1
;
tjn29@cam.ac.uk
;
Francesco Meghini
1
;
Francesca Florio
1
;
Yuu Kimata
1
;
2
;
yk299@cam.ac.uk
关键词:
APC/C
;
proteolysis
;
wingless
;
Wnt
;
Drosophila
;
Nek2
;
eye development
;
Dpp
;
differentiation
;
fate specification
刊名:Developmental Cell
出版年:2017
3.
Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent
Nek2
inhibitors with in vitro and in vivo antitumor activities
作者:
Jian-Bei Xi
a
;
1
;
Yan-Fen Fang
a
;
1
;
Brendan Frett
b
;
1
;
Meng-Li Zhu
a
;
Tong Zhu
a
;
Yan-Nan Kong
a
;
Feng-Jie Guan
a
;
Yun Zhao
a
;
Xiong-Wen Zhang
a
;
xwzhang@sat.ecnu.edu.cn
;
Hong-yu Li
b
;
HLi2@uams.ed
;
Ming-Liang Ma
a
;
mlma@brain.ecnu.edu.cn
;
Wenhao Hu
a
;
whu@chem.ecnu.edu.cn
关键词:
Nek2
inhibitors
;
Imidazo[1
;
2-a]pyridine
;
Antitumor activity
;
Selectivity
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Transcriptomic analysis of gene expression profiles of stomach carcinoma reveal abnormal expression of mitotic components
作者:
Hongfei Tong
;
Jisheng Wang
;
Hui Chen
;
Zhaohong Wang
;
Henwei Fan
;
Zhonglin Ni
;
chinanister@tom.com
关键词:
Gastric cancer
;
Mitosis
;
Transcriptomic analysis
;
Gene interaction network
;
Co-expression network
刊名:Life Sciences
出版年:2017
5.
Nek2
A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism
作者:
Yao Wang
a
;
e
;
1
;
Yong Li
a
;
1
;
Guanghui Hu
a
;
e
;
Xuan Huang
a
;
Hai Rao
b
;
Xiangyang Xiong
c
;
Zhijun Luo
c
;
Quqin Lu
d
;
Shiwen Luo
a
;
e
;
shiwenluo@ncu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
NIMA-related expressed kinase 2A
;
Suppressor of fused
;
Phosphorylation
;
Transcription factor Gli2
;
Hedgehog signaling pathway
刊名:Cellular Signalling
出版年:2016
6.
Xenopus as a model organism for birth defects—Congenital heart disease and heterotaxy
作者:
Anna R. Duncan
a
;
Mustafa K. Khokha
b
;
mustafa.khokha@yale.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Xenopus
;
Human genetics
;
Disease model
;
Heterotaxy
;
Congenital heart disease
;
galnt11
;
nek2
;
BCOR
刊名:Seminars in Cell & Developmental Biology
出版年:2016
7.
Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells
作者:
Thanyaporn Dechtawewat
a
;
Atchara Paemanee
b
;
Sittiruk Roytrakul
b
;
Pucharee Songprakhon
a
;
Thawornchai Limjindaporn
c
;
Pa-thai Yenchitsomanus
a
;
Sawanan Saitornuang
d
;
e
;
Chunya Puttikhunt
d
;
e
;
Watchara Kasinrerk
f
;
g
;
Prida Malasit
d
;
e
;
Sansanee Noisakran
d
;
e
;
sansanee@biotec.or.th" class="auth_mail" title="E-mail the corresponding author
关键词:
Dengue virus
;
Nonstructural protein 1
;
Virus&ndash
;
host interaction
;
Virus replication
刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2016
8.
NEK2
phosphorylation antagonizes the microtubule stabilizing activity of centrobin
作者:
Joonhyun Park
;
Kunsoo Rhee
;
rheek@snu.ac.kr
关键词:
NEK2
;
Centrobin
;
Microtubule stabilization
;
Cell spreading
;
Cell migration
刊名:Biochemical and Biophysical Research Communications
出版年:2013
9.
Insight into
Nek2
A activity regulation and its pharmacological prospects
作者:
Ambuj Kumar
;
Vidya Rajendran
;
Rao sethumadhavan
;
Rituraj Purohit
关键词:
Nek2
A
;
CEP135
;
C-Nap1
;
Rootelin
;
Mst1/Mst2
;
HSav1
;
Eg5
;
Cancer
;
Inhibitor
;
Activity regulation
;
Functional domains
刊名:Egyptian Journal of Medical Human Genetics
出版年:2013
10.
NEK2
Induces Drug Resistance Mainly through Activation of Efflux Drug Pumps and Is Associated with Poor Prognosis in Myeloma and Other Cancers
作者:
Wen Zhou
1
;
3
;
6
;
Ye Yang
1
;
3
;
6
;
Jiliang Xia
1
;
3
;
6
;
He Wang
1
;
3
;
6
;
Mohamed E. Salama
2
;
Wei Xiong
3
;
Hongwei Xu
1
;
3
;
Shashirekha Shetty
4
;
Tiehua Chen
3
;
Zhaoyang Zeng
3
;
Lei Shi
3
;
Maurizio Zangari
3
;
Rodney Miles
2
;
David Bearss
5
;
Guido Tricot
1
;
guido-tricot@uiowa.edu
;
Fenghuang Zhan
1
;
3
;
fenghuang-zhan@uiowa.edu
刊名:Cancer Cell
出版年:2013
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