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在“Elsevier电子期刊”中，命中：792条，耗时：0.0269871 秒

在所有数据库中总计命中：1,423条

1.Development of spiroguanidine-derived α7 neuronal nicotinic receptor partial agonists

作者：Matthew D. Hill ; ^{matthew.hill@bms.com} ; Haiquan Fang ; Sivarao V. Digavalli ; Francine L. Healy ; Lizbeth Gallagher ; Debra Post-Munson ; Ping Chen ; Joanne Natale ; Yulia Benitex ; Daniel Morgan ; Nicholas Lodge ; Linda Bristow ; John E. Macor ; Richard E. Olson

关键词：α7 nicotinic acetylcholine receptor ; Schizophrenia ; 5-HT3A receptor ; Spiroguanidine ; Immediate early genes

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Structure and Mechanism of Neuronal Nicotinic Acetylcholine Receptors

刊名：Biophysical Journal

出版年：2017

3.Molecular simulation study of the unbinding of α-conotoxin [ϒ4E]GID at the α7 and α4β2 neuronal nicotinic acetylcholine receptors

作者：Abishek Suresh¹ ; Andrew Hung ; ¹ ; ^{andrew.hung@rmit.edu.au}

关键词：Conotoxins ; Nicotinic acetylcholine receptors ; Molecular-dynamics simulations ; Binding-free energy ; Antagonist ; Umbrella-sampling

刊名：Journal of Molecular Graphics and Modelling

出版年：2016

4.Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain

作者：Jie Wu¹ ; ² ; ^{jie.wu@dignityhealth.org" class="auth_mail" title="E-mail the corresponding author} ; Qiang Liu² ; Pei Tang³ ; Jens D. Mikkelsen⁴ ; Jianxin Shen¹ ; Paul Whiteaker² ; Jerrel L. Yakel⁵

关键词：nicotinic acetylcholine receptor ; alpha 7 nicotinic acetylcholine receptor ; nicotine ; acetylcholine ; choline

刊名：Trends in Pharmacological Sciences

出版年：2016

5.SN56 basal forebrain cholinergic neuronal loss after acute and long-term chlorpyrifos exposure through oxidative stress generation; P75^NTR and α₇-nAChRs alterations mediated partially by AChE variants disruption

作者：Javier del Pino^a ; ¹ ; ^{jdelpino@pdi.ucm.es" class="auth_mail" title="E-mail the corresponding author} ; Paula Moyano^b ; ¹ ; Marí ; a José ; Anadon^b ; José ; Manuel Garcí ; a^b ; Marí ; a Jesú ; s Dí ; az^a ; Gloria Gó ; mez^b ; Jimena Garcí ; a^c ; Marí ; a Teresa Frejo^a

关键词：Ach ; acetylcholine ; AChE ; acetylcholine esterase ; AD ; Alzheirmer&rsquo ; s disease ; α7-nAChRs ; 7-nicotinic acetylcholine receptors ; BSA ; bovine serum albumin ; CPF ; chlorpyrifos ; DMEM ; Dulbecco&rsquo ; s Modified Eagle&rsquo ; s Medium ; DMSO ; dimethylsulphoxide ; FBS ; fetal bovine serum ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyl-tetrazolium bromide ; NAC ; N-acetylcysteine ; OP ; organophosphates ; P75NTR ; P75 nerve growth factor receptors ; PBS ; phosphate-buffered saline ; ROS ; reactive oxygen species

刊名：Toxicology

出版年：2016

6.Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

作者：Carlo Matera^a ; Marta Quadri^a ; Miriam Sciaccaluga^b ; Diego Yuri Pomè ; ^a ; Francesca Fasoli^d ; ^e ; Marco De Amici^a ; Sergio Fucile^b ; ^c ; Cecilia Gotti^d ; ^e ; Clelia Dallanoce^a ; ^{clelia.dallanoce@unimi.it" class="auth_mail" title="E-mail the corresponding author} ; Giovanni Grazioso^a

关键词：Neuronal nicotinic acetylcholine receptors ; Molecular modeling ; Design ; Anabaseine-related derivatives ; α3β4 nicotinic ligands ; Binding affinity ; Functional activity/selectivity

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.Analysis of neuronal nicotinic acetylcholine receptor α4β2 activation at the single-channel level

作者：Camila Carignano ; Esteban Pablo Barila ; Guillermo Spitzmaul ; ^{gspitz@criba.edu.ar" class="auth_mail" title="E-mail the corresponding author}

关键词：ACh ; acetylcholine ; BS ; binding site ; HC ; high-conductance ; HS ; high-sensitivity ; LC ; low-conductance ; LS ; low-sensitivity ; nAChRs ; nicotinic acetylcholine receptors

刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes

出版年：2016

8.Effects of nicotinic receptor agonists on bladder afferent nerve activity in an in vitro bladder-pelvic nerve preparation

作者：Yongbei Yu ; ^{yyu407@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Stephanie L. Daugherty ; William C. de Groat

关键词：ACh ; acetylcholine ; AMN ; atropine methyl nitrate ; AP ; action potential ; EPI ; epibatidine ; BAN ; bladder afferent nerve ; MEC ; mecamylamine ; NNR ; neuronal nicotinic receptors ; NO ; nitric oxide ; NOS ; nitric oxide synthase ; PPADS ; pyridoxal-phosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonate

刊名：Brain Research

出版年：2016

9.Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for 伪₄尾₂ neuronal nicotinic acetylcholine receptors

作者：Francesco Deligia^a ; Valeria Deiana^a ; Cecilia Gotti^b ; Paolo Lazzari^c ; ^d ; Mirko E.H. Bottazzi^d ; Luca Pucci^b ; Francesca Fasoli^b ; Giulio Ragusa^a ; Gerard A. Pinna^a ; Gabriele Murineddu^a ; ^{muri@uniss.it" class="auth_mail" title="E-mail the corresponding author}

关键词：3 ; 6-diazabicyclo[3.1.1]heptanes ; Synthesis ; 伪4尾2 neuronal nicotinic acetylcholine receptors selectivity ; Agonism ; Antagonism

刊名：European Journal of Medicinal Chemistry

出版年：2015

10.Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy

作者：Patricio Iturriaga-Vá ; squez^a ; ^{patricio.iturriaga@ufrontera.cl" class="auth_mail" title="E-mail the corresponding author} ; Jans Alzate-Morales^b ; Isabel Bermudez^c ; Rodrigo Varas^e ; Miguel Reyes-Parada^d ; ^e ; ^{miguel.reyes@usach.cl" class="auth_mail" title="E-mail the corresponding author}

关键词：Nicotinic receptor ; Polypharmacology ; Medicinal chemistry ; Drug design ; Orthosteric ligands ; Allosteric ligands

刊名：Pharmacological Research

出版年：2015

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