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Springer电子图书(1)
CNKI学位论文(169)
知网期刊论文(86)
在“
Elsevier电子期刊
”中,
命中:
198
条,耗时:0.029985 秒
在所有数据库中总计命中:
256
条
1.
Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ
receptor
: The studies of design, synthesis, and structure-activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives
作者:
Shigeo Hayashi
;
Shigeo_Hayashi@nifty.com" class="auth_mail" title="E-mail the corresponding author
;
Katsuyo Ohashi
;
Sachiko Mihara
;
Eriko Nakata
;
Chie Emoto
;
Atsuko Ohta
关键词:
Nociceptin/Orphanin FQ (N/OFQ)
;
Human NOP (
ORL1
)
receptor
selective antagonist
;
Multisite interactions with NOP
receptor
;
Metabolic stability
;
HERG potassium ion channel binding
;
Prolong QT interval issues
刊名:European Journal of Medicinal Chemistry
出版年:2016
2.
Association between DNA methylation of S
ORL1
5′-flanking region and mild cognitive impairment in type 2 diabetes mellitus
作者:
Yang Yu
a
;
someso@sina.com
;
Wang Mingjiao
a
;
Xiaohui Yang
a
;
Miao Sui
a
;
Tao Zhang
a
;
Jin Liang
b
;
Xinyi Gu
b
;
Xiaomei Wang
a
关键词:
Mild cognitive impairment
;
S
ORL1
;
Methylation
;
Methylation-specific PCR
刊名:Annales d'Endocrinologie
出版年:2016
3.
Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, G
i/o
-coupled
receptor
function in the hypothalamic control of energy homeostasis
作者:
Virginia Mela
a
;
Amanda Vargas
a
;
Cecilia Meza
a
;
Malika Kachani
b
;
Edward J. Wagner
a
;
ewagner@westernu.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
2-AG
;
2-arachidonoylglycerol
;
AgRP
;
agouti-related peptide
;
AMPK
;
AMP-activated protein kinase
;
ARC
;
hypothalamic arcuate nucleus
;
CRH
;
corticotropin-releasing hormone
;
DSI
;
depolarization-induced suppression of inhibition
;
ERK
;
extracellular signal-regulated protein kinase
;
GIRK
;
G protein-gated
;
inwardly-rectifying K+
;
JAK
;
Janus kinase
;
LHA
;
lateral hypothalamic area
;
MCH
;
melanin-concentrating hormone
;
mEPSC
;
miniature excitatory postsynaptic current
;
nNOS
;
neuronal nitric oxide synthase
;
NP
刊名:Journal of Steroid Biochemistry and Molecular Biology
出版年:2016
4.
SORLA regulates calpain-dependent degradation of synapsin
作者:
Daniela Hartl
a
;
b
;
daniela.hartl@uniklinikum-saarland.de" class="auth_mail" title="E-mail the corresponding author
;
Grit Nebrich
a
;
Oliver Klein
a
;
Heike Stephanowitz
c
;
Eberhard Krause
c
;
Michael Rohe
d
;
michael.rohe@abbvie.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Alzheimer's disease
;
Risk factor
;
Sporadic AD
;
SORLA
;
S
orl1
;
Synapse
刊名:Alzheimer's & Dementia
出版年:2016
5.
Activation of membrane estrogen
receptor
s attenuates opioid
receptor
-like1
receptor
-mediated antinociception via an ERK-dependent non-genomic mechanism
作者:
K.M. Small
;
S. Nag
;
S.S. Mokha
关键词:
ANOVA
;
analysis of variance
;
AUC
;
area under the curve
;
DPN
;
diarylpropionitrile
;
E2BSA
;
尾-estradiol-6-(O-carboxymethyl)oxime
;
bovine serum albumin
;
ERK
;
extracellular signal-regulated kinase
;
GIRK
;
G protein-gated inwardly rectifying potassium channels
;
Gq-mER
;
Gq-coupled mER
;
mERs
;
membrane estrogen
receptor
s
;
OFQ
;
orphanin FQ
;
ORL1
;
opioid
receptor
-like 1
;
OVX
;
ovariectomized
;
PKA
;
protein kinase A
;
PKC
;
protein kinase C
;
PPT
;
propylpyrazoletriol
;
TFL
;
tail flick latencies
刊名:Neuroscience
出版年:26 December, 2013
6.
Quantitative structure activity relationship (QSAR) studies on a series of imidazole derivatives as novel
ORL1
receptor
antagonists
作者:
A.K. Srivastava
;
Neerja Shukla
关键词:
QSAR
;
ORL1
receptor
antagonist
;
Physicochemical property
;
Regression analysis
刊名:Journal of Saudi Chemical Society
出版年:2013
7.
Evaluation of [
18
F]MK-0911, a positron emission tomography (PET) tracer for opioid
receptor
-like 1 (
ORL1
), in rhesus monkey and human
作者:
Eric D. Hostetler
a
;
eric_hostetler@merck.com
;
Sandra Sanabria-Bohó
;
rquez
a
;
Waisi Eng
a
;
Aniket D. Joshi
a
;
Shailendra Patel
a
;
Raymond E. Gibson
a
;
Stacey O'Malley
a
;
Stephen M. Krause
a
;
Christine Ryan
a
;
Kerry Riffel
a
;
Sheng Bi
a
;
Osamu Okamoto
b
;
Hiroshi Kawamoto
b
;
Satoshi Ozaki
b
;
Hisashi Ohta
b
;
Tjibbe de Groot
c
;
Guy Bormans
c
;
Marleen Depré
;
f
;
Jan de Hoon
f
;
Inge De Lepeleire
d
;
Tom Reynders
d
;
Jacquelynn J. Cook
a
;
H. Donald Burns
a
;
Michael Egan
e
;
William Cho
e
;
Koen van Laere
c
;
Richard J. Hargreaves
a
关键词:
Opioid
receptor
like-1
;
NOP
;
PET
;
Monkey
;
Human
;
Fluorine-18
刊名:NeuroImage
出版年:2013
8.
The S
ORL1
polymorphism rs985421 may confer the risk for amnestic mild cognitive impairment and Alzheimer's disease in the Han Chinese population
作者:
Chunhui Jin
a
;
jch1029@126.com" class="auth_mail
;
Lili Zhang
b
;
Yiping Xian
c
;
Xiaowei Liu
a
;
Yue Wu
a
;
Feng Zhang
a
;
Jianzhong Zhu
a
;
Guofu Zhang
a
;
Caixia Chen
a
;
Ronglan Gong
b
;
Lingyun Zhang
b
;
Jianmin Yuan
a
;
Fuquan Zhang
a
;
Lin Tian
a
;
Guoqiang Wang
a
;
Zaohuo Cheng
a
;
chengzaohuo@126.com" class="auth_mail
关键词:
Alzheimer's disease
;
S
ORL1
;
Mild cognitive impairment
;
Polymorphism
;
Han Chinese
刊名:Neuroscience Letters
出版年:20 March, 2014
9.
Association between the S
ORL1
rs2070045 polymorphism and late-onset Alzheimer's disease: Interaction with the ApoE genotype in the Chinese Han population
作者:
Xiaofan Xue
;
Milan Zhang
;
Yicong Lin
;
Erhe Xu
;
Jianping Jia
关键词:
Alzheimer's disease
;
Sortilin-related
receptor
L1
;
Single nucleotide polymorphism
;
Chinese
;
ApoE
刊名:Neuroscience Letters
出版年:24 January, 2014
10.
Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP)
receptor
density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin
作者:
Erwan Le Maî
;
tre
1
;
Nathalie Dourmap
2
;
Catherine Vilpoux
3
;
Romain Leborgne
;
Franç
;
ois Janin
2
;
Jean-Jacques Bonnet
;
Jean Costentin
;
Isabelle Leroux-Nicollet
;
isabelle.leroux@univ-rouen.fr
关键词:
AUC
;
area under the curve
;
DOPAC
;
dihydroxyphenylacetic acid
;
DRN
;
dorsal raphe nucleus
;
HVA
;
homovanillic acid
;
NOP
receptor
;
nociceptin-orphanin FQ
receptor
;
ORL1
receptor
;
opioid
receptor
-like 1
receptor
;
pCPA
;
para-chlorophenylalanine
;
SSRI
;
selective
刊名:Brain Research
出版年:2013
1
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