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CNKI会议论文(67)
CNKI期刊论文0611(43)
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CNKI学位论文(11586)
知网期刊论文(29052)
在“
Elsevier电子期刊
”中,
命中:
8,427
条,耗时:0.0100312 秒
在所有数据库中总计命中:
40,780
条
1.
Simultaneous Inhibition of
PI3K
δ and PI3Kα Induces ABC-DLBCL Regression by Bloc
k
ing BCR-Dependent and -Independent Activation of NF-κB and AKT
作者:
Juliane Paul
1
;
5
;
Maurice Soujon
1
;
5
;
Antje M. Wengner
1
;
Sabine Zitzmann-
K
olbe
1
;
Andrea Sturz
1
;
K
atja Hai
k
e
1
;
K
oh Hui Keng Magdalene
2
;
Sze Huey Tan
3
;
Martin Lange
1
;
Soo Yong Tan
2
;
6
;
Domini
k
Mumberg
1
;
Soon Thye Lim
4
;
K
arl Ziegelbauer
1
;
Ningshu Liu
1
;
ningshu.liu@bayer.com
关键词:
PI3K
α
;
PI3K
δ
;
NF-κB
;
BCR
;
MYD88
;
CARD11
;
DLBCL
;
follicular lymphoma
;
ibrutinib-resistance
;
copanlisib
刊名:Cancer Cell
出版年:2017
2.
La inhibición de la
PI3K
γ protege contra la miocardiopatía diabética en ratones
作者:
Angelo Maffei
a
;
Giuseppe Cifelli
a
;
Raimondo Carnevale
a
;
Roberta Iacobucci
a
;
Fabio Pallante
a
;
Valentina Fardella
a
;
Stefania Fardella
a
;
Emilio Hirsch
b
;
Giuseppe Lembo
a
;
c
;
Daniela Carnevale
a
;
c
;
Daniela.carnevale@uniroma1.it
关键词:
Diabetes mellitus
;
Miocardiopatí
a ;
Fá
;
rmacos en investigació
n ;
Proteí
;
na
PI3K
γ
;
Rató
n
刊名:Revista Española de Cardiología
出版年:2017
3.
PI3K
γ Inhibition Protects Against Diabetic Cardiomyopathy in Mice
作者:
Angelo Maffei
a
;
Giuseppe Cifelli
a
;
Raimondo Carnevale
a
;
Roberta Iacobucci
a
;
Fabio Pallante
a
;
Valentina Fardella
a
;
Stefania Fardella
a
;
Emilio Hirsch
b
;
Giuseppe Lembo
a
;
c
;
Daniela Carnevale
a
;
c
;
Daniela.carnevale@uniroma1.it
关键词:
Diabetes mellitus
;
Cardiomyopathy
;
Investigational drugs
;
PI3K
γ protein
;
Mouse
刊名:Revista Española de Cardiología (English Edition)
出版年:2017
4.
K
inetic modelling of in vitro data of
PI3
K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002
作者:
Alexey Goltsov
a
;
a.goltsov@abertay.ac.u
k
;
Ghassan Tash
k
andi
b
;
s1163633@exseed.ed.ac.u
k
;
Simon P. Langdon
b
;
Simon.Langdon@ed.ac.u
k
;
David J. Harrison
c
;
David.Harrison@st-andrews.ac.u
k
;
James L. Bown
a
;
d
;
j.bown@abertay.ac.u
k
关键词:
K
inetic modelling
;
PI3K
;
mTOR1
;
PTEN
;
Rapamycin
;
BEZ235
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Target regulation of
PI3K
/A
k
t/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
作者:
Sabrina Giacoppo
a
;
Federica Pollastro
b
;
Gianpaolo Grassi
c
;
Placido Bramanti
a
;
Emanuela Mazzon
a
;
emazzon.irccs@gmail.com
关键词:
Cannabidiol
;
Multiple sclerosis
;
PI3K
/A
k
t/mTOR pathway
;
BDNF
;
Inflammation
;
Neuronal survival
刊名:Fitoterapia
出版年:2017
6.
Discovery of triazole aminopyrazines as a highly potent and selective series of
PI3K
δ inhibitors
作者:
Ina Terstiege
a
;
Ina.Terstiege@astrazeneca.com
;
Matthew Perry
a
;
Jens Petersen
b
;
Christian Tyrchan
a
;
Tor Svensson
a
;
Helena Lindmar
k
b
;
Linda Ö
;
ster
b
关键词:
Phosphoinositide 3-
k
inase
;
PI3K
δ inhibitor
;
Aminopyrazine
;
Inflammation
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
7.
Inhibiting
PI3K
-AKt signaling pathway is involved in antitumor effects of ginsenoside Rg3 in lung cancer cell
作者:
Qipeng Xie
a
;
1
;
Huai
k
ai Wen
a
;
1
;
Qiong Zhang
b
;
Weihe Zhou
c
;
Xiaoming Lin
d
;
Deyao Xie
d
;
Yu Liu
d
;
48936053@qq.com
关键词:
Ginsenoside Rg3
;
Lung cancer
;
Apoptosis
;
PI3K
/A
k
t
刊名:Biomedicine & Pharmacotherapy
出版年:2017
8.
Identification of allosteric binding sites for
PI3K
α oncogenic mutant specific inhibitor design
作者:
Michelle S. Miller
a
;
Sweta Maheshwari
b
;
Fiona M. McRobb
c
;
K
enneth W. Kinzler
d
;
L. Mario Amzel
b
;
Bert Vogelstein
d
;
Sandra B. Gabelli
a
;
b
;
e
;
gabelli@jhmi.edu
关键词:
PI
K
3CA
;
PI3K
;
PIP2
;
PIP3
;
Fragment-based drug discovery
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
9.
Quercetin attenuates high fructose feeding-induced atherosclerosis by suppressing inflammation and apoptosis via ROS-regulated
PI3K
/AKT signaling pathway
作者:
Xue-Li Lu
;
1
;
luxli123@126.com
;
Cui-Hua Zhao
1
;
Xin-Liang Yao
;
Han Zhang
关键词:
Quercetin
;
High fructose
;
Atherosclerosis
;
ROS
;
PI3K
/AKT
刊名:Biomedicine & Pharmacotherapy
出版年:2017
10.
Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by
PI3K
-AKT signaling in 3T3-L1 cells
作者:
Mengqing Wu
a
;
b
;
1
;
Dan Liu
a
;
b
;
1
;
Rong Zeng
a
;
b
;
1
;
Tao Xian
a
;
b
;
Yi Lu
a
;
b
;
Guohua Zeng
a
;
b
;
Zhangzetian Sun
c
;
Bowei Huang
c
;
Qiren Huang
a
;
b
;
qrhuang@ncu.edu.cn
关键词:
4E-BP1
;
4E-binding protein1
;
C/EBP
;
CCAAT/ enhancer binding proteins
;
EGCG
;
epigallocatechin-3-gallate
;
FAS
;
fatty acid synthase
;
FOXO1
;
for
k
head box-O1
;
HFD
;
high fat diet
;
IGF
;
insulin-li
k
e growth factor
;
IR
;
insulin resistance
;
IRS1
;
insulin receptor substrate 1
;
MSCs
;
mesenchymal stem cells
;
PGC1
;
PPARγ coactivator 1
;
PI3K
;
phosphatidylinositol 3
k
inase
;
PPARγ
;
peroxisome proliferator activated receptor γ
;
Rb
;
retinoblastoma protein
;
TG
;
triglyceride
;
TIF2
;
transcriptional intermediary facto
刊名:European Journal of Pharmacology
出版年:2017
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