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Springer电子图书(8)
CNKI学位论文(10164)
知网期刊论文(13329)
CNKI会议论文(12)
CNKI期刊论文0611(18)
万方学位论文(3)
在“
Elsevier电子期刊
”中,
命中:
5,239
条,耗时:0.0259885 秒
在所有数据库中总计命中:
23,534
条
1.
Cytokine IL-10, activators of
PI3
-
kinase
, agonists of α-2 adrenoreceptor and antioxidants prevent ischemia-induced cell death in rat hippocampal cultures
作者:
Egor A. Turovsky
;
Maria V. Turovskaya
;
Sergei G. Gaidin
;
Valery P. Zinchenko
;
vpz@mail.ru
关键词:
Ischemia
;
OGD
;
Interleukin-10
;
PI3
-
Kinase
;
Alpha-2 adrenoreceptor
;
Antioxidant enzyme
;
Neuroprotective agents
;
Hippocampal cell culture
;
Global [Ca2+]i increase
;
Fura-2
;
Ca2+ imaging
;
Cell survival
刊名:Archives of Biochemistry and Biophysics
出版年:2017
2.
Compound Selectivity and Target Residence Time of
Kinase
Inhibitors Studied with Surface Plasmon Resonance
作者:
Nicole Willemsen-Seegers
1
;
Joost C.M. Uitdehaag
1
;
Martine B.W. Prinsen
1
;
Judith R.F. de Vetter
1
;
Jos de Man
1
;
Masaaki Sawa
2
;
Yusuke Kawase
2
;
Rogier C. Buijsman
1
;
Guido J.R. Zaman
1
;
guido.zaman@ntrc.nl
关键词:
FDA
;
US Food and Drug Administration
;
EGFR
;
epidermal growth factor receptor
;
BTK
;
Bruton's tyrosine
kinase
;
SPR
;
surface plasmon resonance
;
PI3
K
;
phosphoinositide 3-
kinase
;
SD
;
standard deviation
;
SE
;
standard error
;
PI3
K
;
phosphoinositide 3-
kinase
;
SPR
;
surface plasmon resonance
刊名:Journal of Molecular Biology
出版年:2017
3.
Class I phosphatidylinositol 3-
kinase
inhibitors for cancer therapy
作者:
Wennan Zhao
&dagger
;
;
Yuling Qiu
&dagger
;
;
Dexin Kong
;
kongdexin@tmu.edu.cn
关键词:
Phosphatidylinositol 3-
kinase
;
PI3
K inhibitor
;
Drug candidate
;
Cancer therapy
;
PI3
K/mTOR selectivity
;
Anticancer
刊名:Acta Pharmaceutica Sinica B
出版年:2017
4.
Skeletal muscle
PI3
K p110β regulates expression of AMP-activated protein
kinase
作者:
Ronald W. Matheny Jr.
;
ronald.w.matheny.civ@mail.mil
;
Mary N. Abdalla
;
Alyssa V. Geddis
;
Luis A. Leandry
;
Christine M. Lynch
关键词:
AMP-activated protein
kinase
(AMPK)
;
Phosphoinositide 3-
kinase
(
PI3
K)
;
Myoblast
;
Skeletal muscle
刊名:Biochemical and Biophysical Research Communications
出版年:2017
5.
Hematopoietic cell
kinase
(HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/
PI3
K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway
作者:
Fernanda Marconi Roversi
a
;
Fernando Vieira Pericole
a
;
Joã
;
o Agostinho Machado-Neto
a
;
Adriana da Silva Santos Duarte
a
;
Ana Leda Longhini
a
;
Flá
;
via Adolfo Corrocher
a
;
Bruna Palodetto
a
;
Karla Priscila Ferro
a
;
Renata Giardini Rosa
a
;
Mariana Ozello Baratti
a
;
Sergio Verjovski-Almeida
b
;
Fabiola Traina
a
;
1
;
Alessio Molinari
c
;
Maurizio Botta
c
;
Sara Teresinha Olalla Saad
a
;
sara@unicamp.br
关键词:
Hematopoietic cell
kinase
;
Myelodysplastic syndrome
;
Acute myeloid leukemia
;
Hematopoietic stem cells
;
Erythroid differentiation
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
6.
Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by
PI3
K-AKT signaling in 3T3-L1 cells
作者:
Mengqing Wu
a
;
b
;
1
;
Dan Liu
a
;
b
;
1
;
Rong Zeng
a
;
b
;
1
;
Tao Xian
a
;
b
;
Yi Lu
a
;
b
;
Guohua Zeng
a
;
b
;
Zhangzetian Sun
c
;
Bowei Huang
c
;
Qiren Huang
a
;
b
;
qrhuang@ncu.edu.cn
关键词:
4E-BP1
;
4E-binding protein1
;
C/EBP
;
CCAAT/ enhancer binding proteins
;
EGCG
;
epigallocatechin-3-gallate
;
FAS
;
fatty acid synthase
;
FOXO1
;
forkhead box-O1
;
HFD
;
high fat diet
;
IGF
;
insulin-like growth factor
;
IR
;
insulin resistance
;
IRS1
;
insulin receptor substrate 1
;
MSCs
;
mesenchymal stem cells
;
PGC1
;
PPARγ coactivator 1
;
PI3
K
;
phosphatidylinositol 3
kinase
;
PPARγ
;
peroxisome proliferator activated receptor γ
;
Rb
;
retinoblastoma protein
;
TG
;
triglyceride
;
TIF2
;
transcriptional intermediary facto
刊名:European Journal of Pharmacology
出版年:2017
7.
SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-
kinase
delta (
PI3
Kδ) inhibitors
作者:
Manman Wei
a
;
c
;
1
;
Xi Zhang
b
;
1
;
Xiang Wang
b
;
Zilan Song
a
;
Jian Ding
b
;
Ling-Hua Meng
b
;
lhmeng@simm.ac.cn
;
Ao Zhang
a
;
c
;
aozhang@simm.ac.cn
关键词:
Chronic lymphocytic leukemia
;
PI3
Kδ
;
Structure-activity relationship
;
5-Alkynyl
;
Quinazolinone
刊名:European Journal of Medicinal Chemistry
出版年:2017
8.
Inhibition of Focal Adhesion
Kinase
on Hepatic Stellate-cell Adhesion and Migration
作者:
Yan Wang
;
MD
;
PhD
;
Junji Ma
;
MD
;
PhD
;
Lei Chen
;
MD
;
PhD
;
Xiao-Li Xie
;
PhD
;
Huiqing Jiang
;
MD
;
PhD
;
jianghuiqing1959@sina.com
关键词:
Hepatic stellate cells
;
Adhesion
;
Migration
;
Focal adhesion
kinase
&ndash
;
related non
kinase
;
Phosphatidylinositol 3-
kinase
刊名:The American Journal of the Medical Sciences
出版年:2017
9.
Discovery of triazole aminopyrazines as a highly potent and selective series of
PI3
Kδ inhibitors
作者:
Ina Terstiege
a
;
Ina.Terstiege@astrazeneca.com
;
Matthew Perry
a
;
Jens Petersen
b
;
Christian Tyrchan
a
;
Tor Svensson
a
;
Helena Lindmark
b
;
Linda Ö
;
ster
b
关键词:
Phosphoinositide 3-
kinase
;
PI3
Kδ inhibitor
;
Aminopyrazine
;
Inflammation
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
10.
Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective
PI3
kinase
inhibitors
作者:
Jackie D. Kendall
a
;
b
;
j.kendall@auckland.ac.nz
;
Anna C. Giddens
a
;
Kit Yee Tsang
a
;
Elaine S. Marshall
a
;
Claire L. Lill
c
;
Woo-Jeong Lee
c
;
Sharada Kolekar
c
;
Mindy Chao
c
;
Alisha Malik
c
;
Shuqiao Yu
c
;
Claire Chaussade
b
;
c
;
d
;
Christina Buchanan
b
;
c
;
Stephen M.F. Jamieson
a
;
b
;
Gordon W. Rewcastle
a
;
b
;
Bruce C. Baguley
a
;
b
;
William A. Denny
a
;
b
;
Peter R. Shepherd
b
;
c
关键词:
NKJYYWGDGSKPEW-LPYMAVHISA-N
;
AOXAAEQFLNMCLC-BUVRLJJBSA-N
;
WBWLQGYBHWVMKE-DHRITJCHSA-N
;
MXOGXVOOBVIVJW-YDZHTSKRSA-N
;
AZJHDRSPNKBZGF-MFKUBSTISA-N
;
QIGFDKVDGDNYSS-LGJNPRDNSA-N
;
QPTBMDPOZNSWEZ-WSDLNYQXSA-N
;
OCKIBXWFWFCVNS-YDZHTSKRSA-N
;
UZWYFVJGBGJHHK-OEAKJJBVSA-N
;
IHHGTHQQCPWJCF-BUVRLJJBSA-N
;
LAWUZULWVPIZEA-PCLIKHOPSA-N
;
KJKKEUXQKMRBSJ-YZSQISJMSA-N
;
PJBLMNWKWHJQJT-PCLIKHOPSA-N
;
FCUSNDJMENFTMM-YZSQISJMSA-N
;
JXBONZLAZJXGLS-VULFUBBASA-N
;
VZUIUZAIADXPHJ-VULFUBBASA-N
;
VSPKBGAMPVYLDO-VULFUBBASA-N
;
VWPPTJM
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
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