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在“Elsevier电子期刊”中，命中：2条，耗时：0.0639692 秒

1.Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

作者：Christoffer Bengtsson^a ; Stefan Blaho^a ; David Blomberg Saitton^a ; Kay Brickmann^a ; Johan Broddefalk^a ; Ö ; jvind Davidsson^a ; Tomas Drmota^a ; Rutger Folmer^a ; Kenth Hallberg^a ; Stefan Hallé ; n^a ; Ragnar Hovland^a ; Emre Isin^a ; Petra Johannesson^a ; Bengt Kull^a ; Lars-Olof Larsson^a ; Lars Lö ; fgren^a ; Kristina E. Nilsson^a ; Tobias Noeske^a ; Nick Oakes^a ; Alleyn T. Plowright ; ^a ; ^{alleyn.plowright@astrazeneca.com"" rel=""nofollow} ; Volker Schnecke^a ; Pernilla St&#xe5 ; hlberg^a ; Pernilla Sö ; rme^a ; Hong Wan^a ; Eric Wellner^a ; Linda Ö ; ster^a

关键词：Acetyl-CoA carboxylase ; Malonyl-CoA ; Ligand lipophilicity efficiency ; Quinoline

刊名：Bioorganic and Medicinal Chemistry

出版年：2011

2.Discovery of N-(1-adamantyl)-2-(4-alkylpiperazin-1-yl)acetamide derivatives as T-type calcium channel (Ca_v3.2) inhibitors

作者：Fabrizio Giordanetto^a ; ^{fabrizio.giordanetto@astrazeneca.com"" rel=""nofollow} ; Laurent Knerr^a ; Nidhal Selmi^a ; Antonio Llinà ; s^b ; Anders Lindqvist^c ; Qing-Dong Wang^c ; Pernilla St&#xe5 ; hlberg^a ; Fredrik Thorstensson^a ; Victoria Ullah^a ; Kristina Nilsson^a ; Gavin O’ ; Mahony^a ; Å ; got Hö ; gberg^c ; Emma Lindhardt^b ; Annika Å ; strand^c ; Gö ; ran Duker^c

关键词：Calcium channel inhibition ; Ca_v3.2 ; T-type calcium channels

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

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