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内部出版物
CNKI学位论文(558)
知网期刊论文(204)
在“
Elsevier电子期刊
”中,
命中:
253
条,耗时:0.0199886 秒
在所有数据库中总计命中:
762
条
1.
Novel triclabendazole
prodrug
: A highly water soluble alternative for the treatment of fasciolosis
作者:
Miguel Flores-Ramos
a
;
Froylá
;
n Ibarra-Velarde
b
;
Helgi Jung-Cook
a
;
Alicia Herná
;
ndez-Campos
a
;
Yolanda Vera-Montenegro
b
;
Rafael Castillo
a
;
rafaelc@unam.mx
关键词:
Triclabendazole
;
Fasciola hepatica
;
Prodrug
;
Benzimidazole
;
Phosphonooxymethyl
;
Fasciolicidal activity
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Novel
prodrug
s with a spontaneous cleavable guanidine moiety
作者:
Yoshio Hamada
;
pynden@gmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Guanidino acid
;
Phenytoin
;
Prodrug
;
Quinine
;
Sulfa drug
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
3.
Modulating lipophilicity of rohitukine via
prodrug
approach:
Pre
paration, characterization, and in vitro enzymatic hydrolysis in biorelevant media
作者:
Vikas Kumar
a
;
b
;
Sonali S. Bharate
a
;
sonalibharate@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Ram A. Vishwakarma
b
;
c
;
ram@iiim.ac.in" class="auth_mail" title="E-mail the corresponding author
关键词:
log D
;
distribution coefficient
;
log P
;
partition coefficient
;
NCEs
;
new chemical entities
;
PBS
;
phosphate
buffer saline
;
SGF
;
Simulated gastric fluid
;
SIF
;
Simulated intestinal fluid
;
RP-HPLC
;
reverse-phase high-performance liquid chromatography
;
tR
;
retention time
;
UV
;
ultraviolet
;
HMBC
;
Heteronuclear Multiple Bond Correlation
;
GI50
;
Concentration for 50% growth inhibition
刊名:European Journal of Pharmaceutical Sciences
出版年:2016
4.
Activation of multiple chemotherapeutic
prodrug
s by the natural enzymolome of tumour-localised probiotic bacteria
作者:
Panos Lehouritis
a
;
1
;
Michael Stanton
a
;
1
;
Florence O. McCarthy
b
;
Matthieu Jeavons
a
;
Mark Tangney
a
;
m.tangney@ucc.ie" class="auth_mail" title="E-mail the corresponding author
关键词:
Cancer
;
Therapy
;
Targeting
;
Chemotherapy
;
GDEPT
刊名:Journal of Controlled Release
出版年:2016
5.
Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-
prodrug
therapy
作者:
Alexandra M. Mowday
a
;
Amir Ashoorzadeh
a
;
Elsie M. Williams
b
;
1
;
Janine N. Copp
b
;
2
;
Shevan Silva
a
;
Matthew R. Bull
a
;
Maria R. Abbattista
a
;
Robert F. Anderson
a
;
c
;
Jack U. Flanagan
a
;
c
;
Christopher P. Guise
a
;
c
;
David F. Ackerley
b
;
c
;
Jeff B. Smaill
a
;
c
;
Adam V. Patterson
a
;
c
;
a.patterson@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author
关键词:
PR-104 (PubChem CID
;
11455973)
;
PR-104A (PubChem CID
;
9848786)
;
SN34037 (PubChem CID
;
73671441)
;
SN34507 (PubChem CID
;
90043967)
;
SN35539 (PubChem CID
;
90043246)
刊名:Biochemical Pharmacology
出版年:2016
6.
Simultaneous determination of curcumin diethyl disuccinate and its active metabolite curcumin in rat plasma by LC-MS/MS: Application of esterase inhibitors in the stabilization of an ester-containing
prodrug
作者:
Pahweenvaj Ratnatilaka Na Bhuket
a
;
Nuansri Niwattisaiwong
b
;
c
;
Patanachai Limpikirati
b
;
Phisit Khemawoot
d
;
Pasarapa Towiwat
d
;
Boonsri Ongpipattanakul
e
;
f
;
Pornchai Rojsitthisak
b
;
pornchai.r@chula.ac.th" class="auth_mail" title="E-mail the corresponding author
关键词:
CDD
;
curcumin diethyl disuccinate
;
CUR
;
curcumin
;
DMC
;
dimethylcurcumin
;
IS
;
internal standard
刊名:Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年:2016
7.
Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear
作者:
Naila El Kechai
a
;
naila.el-kechai@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Elisabeth Mamelle
b
;
c
;
elisabeth.mamelle@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Yann Nguyen
b
;
c
;
yann.nguyen@inserm.fr" class="auth_mail" title="E-mail the corresponding author
;
Nicolas Huang
a
;
nicolas.huang@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Valé
;
rie Nicolas
d
;
valerie.nicolas@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Pierre Chaminade
e
;
pierre.chaminade@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Sté
;
phanie Yen-Nicolaÿ
;
e
;
stephanie.nicolay@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Claire Gueutin
a
;
claire.gueutin@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Benjamin Granger
f
;
benjamin.granger@aphp.fr" class="auth_mail" title="E-mail the corresponding author
;
Evelyne Ferrary
b
;
evelyne.ferrary@inserm.fr" class="auth_mail" title="E-mail the corresponding author
;
Florence Agnely
a
;
1
;
florence.agnely@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
;
Amé
;
lie Bochot
a
;
1
;
amelie.bochot@u-psud.fr" class="auth_mail" title="E-mail the corresponding author
关键词:
Chol
;
cholesterol
;
DSPE-PEG2000
;
1
;
2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly-(ethyleneglycol)-2000]
;
Dex
;
dexamethasone
;
DexP
;
dexamethasone
phosphate
;
DLS
;
dynamic light scattering
;
EPC
;
egg phosphatidylcholine
;
Flu
;
flumethasone
;
HA
;
hyaluronic acid
;
Lip
;
liposomes
;
LC&ndash
;
MS
;
liquid chromatography coupled to mass spectroscopy
;
PE
;
phosphatidylethanolamine
;
Rh
;
rhodamine
;
RW
;
round window
刊名:Journal of Controlled Release
出版年:2016
8.
The role of the equatorial ligands for the redox behavior, mode of cellular accumulation and cytotoxicity of platinum(IV)
prodrug
s
作者:
Simone Gö
;
schl
a
;
Hristo P. Varbanov
a
;
b
;
hristo.varbanov@univie.ac.at" class="auth_mail" title="E-mail the corresponding author
;
Sarah Theiner
a
;
c
;
Michael A. Jakupec
a
;
c
;
michael.jakupec@univie.ac.at" class="auth_mail" title="E-mail the corresponding author
;
Markus Galanski
a
;
Bernhard K. Keppler
a
;
c
关键词:
AA
;
ascorbic acid
;
DNA
;
deoxyribonucleic acid
;
FBS
;
fetal bovine serum
;
GSH
;
glutathione
;
ICP-MS
;
inductively coupled plasma mass spectrometry
;
MEM
;
minimum essential medium
;
MTT
;
3-(4
;
5-dimethylthiazol-2-yl)-2
;
5-diphenyltetrazolium bromide
;
NMR
;
nuclear magnetic resonance
;
oc
;
open circular
;
PBS
;
Dulbecco's
phosphate
-buffered saline
;
ROS
;
reactive oxygen species
;
RPMI
;
Roswell Park Memorial Institute medium
;
sc
;
supercoiled
;
SD
;
standard deviation
;
TBE
;
Tris-Borate-EDTA
;
TE
;
Tris-EDTA
刊名:Journal of Inorganic Biochemistry
出版年:2016
9.
Terli
pre
ssin, a vasoactive
prodrug
recommended in hepatorenal syndrome, is an agonist of human V1, V2 and V1B receptors: Implications for its safety profile
作者:
Pascal H. Colson
;
a
;
c
;
1
;
p-colson@chu-montpellier.fr" class="auth_mail" title="E-mail the corresponding author
;
Anne Virsolvy
b
;
1
;
anne.virsolvy@inserm.fr" class="auth_mail" title="E-mail the corresponding author
;
Philippe Gaudard
b
;
c
;
p-gaudard@chu-montpellier.fr" class="auth_mail" title="E-mail the corresponding author
;
Azzouz Charrabi
b
;
azzouz.charrabi@inserm.fr" class="auth_mail" title="E-mail the corresponding author
;
Maithé
;
Corbani
a
;
maithe.corbani@igf.cnrs.fr" class="auth_mail" title="E-mail the corresponding author
;
Maxime J. Maniè
;
re
a
;
m.maniere@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Sylvain Richard
b
;
sylvain.richard@inserm.fr" class="auth_mail" title="E-mail the corresponding author
;
Gilles Guillon
a
;
gilles.guillon@igf.cnrs.fr" class="auth_mail" title="E-mail the corresponding author
关键词:
Terli
pre
ssin
;
PubChem CID
;
72081
;
[Arginine8]Vaso
pre
ssin
;
PubChem CID
;
90488786
;
[Lysine8]Vaso
pre
ssin
;
PubChem CID
;
90488785
;
SR49059
;
PubChem CID
;
60943
刊名:Pharmacological Research
出版年:2016
10.
The vascular disrupting activity of OXi8006 in endothelial cells and its
phosphate
prodrug
OXi8007 in breast tumor xenografts
作者:
Tracy E. Strecker
a
;
1
;
Samuel O. Odutola
b
;
1
;
Ramona Lopez
c
;
Morgan S. Cooper
a
;
Justin K. Tidmore
a
;
Amanda K. Charlton-Sevcik
a
;
Li Li
c
;
Matthew T. MacDonough
a
;
Mallinath B. Hadimani
a
;
Anjan Ghatak
a
;
&dagger
;
;
Li Liu
c
;
David J. Chaplin
d
;
Ralph P. Mason
c
;
Kevin G. Pinney
a
;
b
;
Mary Lynn Trawick
a
;
b
;
mary_lynn_trawick@baylor.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ANOVA
;
analysis of variance
;
BLI
;
bioluminescence imaging
;
CA4
;
combretastatin A-4
;
CA4P
;
combretastatin A-4
phosphate
;
DAPI
;
4&prime
;
6-diamidino-2-phenylindole
;
DMSO
;
dimethyl sulfoxide
;
DTT
;
dithiothreitol
;
FAK
;
focal adhesion kinase
;
FDA
;
Federal Drug Administration
;
FITC
;
fluorescein isothiocyanate
;
GI50
;
median growth inhibitory concentration
;
HRP
;
horseradish peroxidase
;
HUVEC
;
human umbilical vein endothelial cells
;
MLC
;
myosin light chain
;
NMII
;
non-muscle myosin II
;
OXi8006
;
2-(3&prime
刊名:Cancer Letters
出版年:2015
1
2
3
4
5
6
7
8
9
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