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在“Elsevier电子期刊”中，命中：7,265条，耗时：小于0.01 秒

在所有数据库中总计命中：1条

1.Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

2.The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3

作者：Jacob A. McPhail¹ ; Erik H. Ottosen¹ ; Meredith L. Jenkins¹ ; John E. Burke¹ ; ² ; ^{jeburke@uvic.ca}

关键词：lipid signaling ; phosphatidylinositol 4 kinase ; PI4K ; PI4KB ; ACBD3 ; phosphoinositide ; X-ray crystallography ; hydrogen-deuterium exchange mass spectrometry ; HDX-MS ; picornaviruses

刊名：Structure

出版年：2017

3.Microsatellite polymorphism located immediately upstream of the phosphatidylinositol glycan, class K gene (PIGK) affects its expression, which correlates with tyrosinase activity in human melanocytes

作者：Ken Okamura ; ^{k-okamura@med.id.yamagata-u.ac.jp} ; Masahiro Hayashi ; Yuko Abe ; Yuta Araki ; Yutaka Hozumi ; Tamio Suzuki

关键词：GPI ; Melanocyte ; Microsatellite ; PIGK ; Tyrosinase activity

刊名：Journal of Dermatological Science

出版年：2017

4.Inhibition of Focal Adhesion Kinase on Hepatic Stellate-cell Adhesion and Migration

作者：Yan Wang ; MD ; PhD ; Junji Ma ; MD ; PhD ; Lei Chen ; MD ; PhD ; Xiao-Li Xie ; PhD ; Huiqing Jiang ; MD ; PhD ; ^{jianghuiqing1959@sina.com}

关键词：Hepatic stellate cells ; Adhesion ; Migration ; Focal adhesion kinase&ndash ; related nonkinase ; Phosphatidylinositol 3-kinase

刊名：The American Journal of the Medical Sciences

出版年：2017

5.Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity

作者：Meng Cai^a ; Keqing Wang^a ; Colin E. Murdoch^a ; Yuchun Gu^a ; ^b ; Asif Ahmed^a ; ^{asif.ahmed@aston.ac.uk}

关键词：Vascular endothelial growth factor (VEGF) ; VEGF receptors ; Heterodimers ; Phosphatidylinositol 3-kinase (PI3K) ; Angiogenesis

刊名：Vascular Pharmacology

出版年：2017

6.Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells

作者：Mengqing Wu^a ; ^b ; ¹ ; Dan Liu^a ; ^b ; ¹ ; Rong Zeng^a ; ^b ; ¹ ; Tao Xian^a ; ^b ; Yi Lu^a ; ^b ; Guohua Zeng^a ; ^b ; Zhangzetian Sun^c ; Bowei Huang^c ; Qiren Huang^a ; ^b ; ^{qrhuang@ncu.edu.cn}

关键词：4E-BP1 ; 4E-binding protein1 ; C/EBP ; CCAAT/ enhancer binding proteins ; EGCG ; epigallocatechin-3-gallate ; FAS ; fatty acid synthase ; FOXO1 ; forkhead box-O1 ; HFD ; high fat diet ; IGF ; insulin-like growth factor ; IR ; insulin resistance ; IRS1 ; insulin receptor substrate 1 ; MSCs ; mesenchymal stem cells ; PGC1 ; PPARγ coactivator 1 ; PI3K ; phosphatidylinositol 3 kinase ; PPARγ ; peroxisome proliferator activated receptor γ ; Rb ; retinoblastoma protein ; TG ; triglyceride ; TIF2 ; transcriptional intermediary facto

刊名：European Journal of Pharmacology

出版年：2017

7.Nanosecond pulsed electric field induced dose dependent phosphatidylinositol-_4,5-bisphosphate signaling and intracellular electro-sensitization

作者：Gleb P. Tolstykh^a ; ^{gleb.tolstykh.ctr@us.af.mil} ; Melissa Tarango^a ; Caleb C. Roth^b ; Bennett L. Ibey^b

关键词：Nanosecond electric pulses ; PIP2 depletion ; Diacylglycerol ; Inositol-14 ; 5-trisphosphate ; Nanoporation ; Membrane

刊名：Biochimica et Biophysica Acta (BBA) - Biomembranes

出版年：2017

8.Microcystin-LR promotes epithelial-mesenchymal transition in colorectal cancer cells through PI3-K/AKT and SMAD2

作者：Yan Ren^a ; ¹ ; Mengli Yang^a ; ¹ ; Meng Chen^b ; ^c ; Qiangqiang Zhu^a ; Lihua Zhou^a ; Wei Qin^a ; Ting Wang^a ; ^{wangting@njmu.edu.cn}

关键词：MC-LR ; microcystin-LR ; EMT ; epithelial-mesenchymal transition ; PI3-K/AKT ; phosphatidylinositol 3-kinase/Akt ; qPCR ; quantitative real-time polymerase chain reaction ; siRNA ; small interfering RNA ; MMP ; matrix metalloproteinase

刊名：Toxicology Letters

出版年：2017

9.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

10.Silymarin exerts antifungal effects via membrane-targeted mode of action by increasing permeability and inducing oxidative stress

作者：Dae Gyu Yun ; Dong Gun Lee ; ^{dglee222@knu.ac.kr}

关键词：MIC ; minimal inhibitory concentration ; PBS ; phosphate-buffered saline ; LUV ; large unilamellar vesicles ; PC ; phosphatidylcholine ; PE ; phosphatidylethanolamine ; PI ; phosphatidylinositol ; FD ; fluorescein isothiocyanate-labeled dextran ; ROS ; reactive oxygen species ; H2DCFDA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; MDA ; malondialdehyde ; TBA ; thiobarbituric acid ; DiBAC4(3) ; bis-(1 ; 3-dibutylbarbituric acid) trimethineoxonol ; DPH ; 1 ; 6-diphenyl-13 ; 5-hexatriene

刊名：Biochimica et Biophysica Acta (BBA) - Biomembranes

出版年：2017

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