设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
中国地质文献-英文(3)
CNKI学位论文(23133)
知网期刊论文(4725)
CNKI会议论文(10)
CNKI期刊论文0611(69)
万方学位论文(1)
在“
Elsevier电子期刊
”中,
命中:
1,914
条,耗时:0.188907 秒
在所有数据库中总计命中:
27,941
条
1.
Diversity selection, screening and
quantitative
structure
-
activity
relationship
s of osmolyte-like additive effects on the thermal stability of a monoclonal antibody
作者:
Olubukayo-Opeyemi Oyetayo
a
;
oyetayophdhbc@gmail.com
;
Oscar Mé
;
ndez-Lucio
b
;
Andreas Bender
b
;
Hans Kiefer
a
关键词:
mAb
;
Monoclonal antibody
;
MOE
;
Molecular Operating Environment
;
MDS
;
Multi-dimensional scaling
;
QSAR
;
Quantitative
structure
&ndash
;
activity
relationship
;
DSC
;
Differential scanning calorimetry
;
DSF
;
Differential scanning fluorimetry
;
DMSO
;
Dimethyl sulfoxide
;
NaOH
;
Sodium hydroxide
;
HCl
;
Hydrochloric acid
;
LOO-CV
;
Leave-one-out cross-validation
;
PCA
;
Principal components analysis
;
PLS
;
Partial least squares
;
TMAO
;
Trimethylamine N-oxide
;
Tm
;
Melting temperature
;
TS potency
;
Thermal stabilization
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
2.
An orientation sensitive approach in biomolecule interaction
quantitative
structure
-
activity
relationship
modeling and its application in ion-exchange chromatography
作者:
Jö
;
rg Kittelmann
a
;
Katharina M.H. Lang
a
;
Marcel Ottens
b
;
Jü
;
rgen Hubbuch
a
;
Juergen.Hubbuch@kit.edu
关键词:
Quantitative
structure
&ndash
;
activity
relationship
(QSAR)
;
Predictive modeling
;
Ion-exchange chromatography
;
Binding orientation
;
Retention modeling
;
Isotherm
刊名:Journal of Chromatography A
出版年:2017
3.
Analysis of positions and substituents on genotoxicity of fluoroquinolones with
quantitative
structure
-
activity
relationship
and 3D Pharmacophore model
作者:
Chen Fengxian
;
Hai Reti
;
hairetibeihua@outlook.com
关键词:
Fluoroquinolones
;
Genotoxicity
;
Quantitative
structure
-
activity
relationship
;
Full factorial experimental design
;
Pharmacophore model
刊名:Ecotoxicology and Environmental Safety
出版年:2017
4.
Investigation and prediction of protein precipitation by polyethylene glycol using
quantitative
structure
-
activity
relationship
models
作者:
Frank Hä
;
mmerling
frank.haemmerling@kit.edu
;
Christopher Ladd Effio
;
Sebastian Andris
;
Jö
;
rg Kittelmann
;
Jü
;
rgen Hubbuch
;
juergen.hubbuch@kit.edu
;
关键词:
Polyethylene glycol
;
Precipitation
;
Quantitative
structure
&ndash
;
activity
relationship
(QSAR)
;
Semi-mechanistic modeling
;
Monoclonal antibody
刊名:Journal of Biotechnology
出版年:2017
5.
Modification of polychlorinated phenols and evaluation of their toxicity, biodegradation and bioconcentration using three-dimensional
quantitative
structure
-
activity
relationship
models
作者:
Lidan Tong
a
;
Lixin Guo
a
;
glx69@163.com
;
Xiaojun Lv
b
;
Yu Li
c
;
liyuxx8@hotmail.com
关键词:
Pentachlorophenol
;
Three-dimensional
quantitative
structure
&ndash
;
activity
relationship
;
Molecular design
;
Biotoxicity
;
Bioconcentration
;
Biodegradation
刊名:Journal of Molecular Graphics and Modelling
出版年:2017
6.
Antitumor
activity
of 3,4-ethylenedioxythiophene derivatives and
quantitative
structure
-
activity
relationship
analysis
作者:
Marijana Jukić
a
;
marijanajukic@mefos.hr
;
Vesna Rastija
b
;
vrastija@pfos.hr
;
Teuta Opačak-Bernardi
a
;
tbernardi@mefos.hr
;
Ivana Stolić
c
;
stolic@vef.hr
;
Luka Krstulović
c
;
lkrstulovic@vef.hr
;
Miroslav Bajić
c
;
mbajic@vef.hr
;
Ljubica Glava&scaron
;
-Obrovac
a
;
lgobrovac@mefos.hr
关键词:
Antitumor agents
;
Heterocycles
;
Computational chemistry
;
QSAR
;
Drug research
;
Cell culturing
刊名:Journal of Molecular
Structure
出版年:2017
7.
Novel anti-tumour barringenol-like triterpenoids from the husks of Xanthoceras sorbifolia Bunge and their three dimensional
quantitative
structure
activity
relationship
s analysis
作者:
Da Wang
a
;
Dan Su
a
;
Bin Yu
a
;
Chuming Chen
b
;
Li Cheng
a
;
Xianzhe Li
a
;
Ronggang Xi
c
;
Huiyuan Gao
a
;
1
;
sypugaohy@163.com
;
Xiaobo Wang
c
;
wxbbenson0653@163.com
关键词:
Xanthoceras sorbifolia Bunge
;
Barrigenol-type triterpenoid
;
Antitumor activities
;
CoMFA
;
CoMSIA
;
Health benefits
刊名:Fitoterapia
出版年:2017
8.
Quantitative
structure
-
activity
relationship
and molecular docking studies of a series of quinazolinonyl analogues as inhibitors of gamma amino butyric acid aminotransferase
作者:
Usman Abdulfatai
;
faithyikare4me@gmail.com
;
Adamu Uzairu
;
Sani Uba
关键词:
QSAR method
;
Gamma aminobutyric acid aminotransferase
;
Molecular docking
;
Density functional theory
;
Anticonvulsant
;
Genetic function algorithm
刊名:Journal of Advanced Research
出版年:2017
9.
Quantitative
structure
activity
relationship
study of p38α MAP kinase inhibitors
作者:
Eslam Pourbasheer
a
;
Sajjad Ahmadpour
b
;
Rohollah Zare-Dorabei
c
;
Mehdi Nekoei
d
;
nekoei_m1@yahoo.com
关键词:
QSAR
;
Genetic algorithm
;
Stepwise
;
Multiple linear regression
;
Pyrazole derivative
刊名:Arabian Journal of Chemistry
出版年:2017
10.
Synthesis, evaluation and
quantitative
structure
-
activity
relationship
(QSAR) analysis of Wogonin derivatives as cytotoxic agents
作者:
Jinlei Bian
1
;
Tinghan Li
1
;
Tianwei Weng
;
Jubo Wang
;
Yu Chen
;
Zhiyu Li
;
zhiyuli@cpu.edu.cn
关键词:
Wogonin
;
QSAR
;
Cytotoxic
;
Flavonoid
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
1
2
3
4
5
6
7
8
9
按检索点细分(1914)
题名(366)
关键词(494)
文摘(1483)
按出版年细分(1914)
2027年及以后(45)
2017年(27)
2016年(75)
2015年(16)
2014年(1)
2013年(107)
2012年(95)
2011年(83)
2010年(141)
2009年(129)
2008年(135)
2007年(109)
2006年(96)
2005年(107)
2004年(94)
2003年(104)
2002年(86)
2001年(63)
2000年(63)
2000年及以前(338)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.