设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
CNKI会议论文(3)
CNKI学位论文(9671)
CNKI期刊论文0611(28)
知网期刊论文(1749)
在“
Elsevier电子期刊
”中,
命中:
812
条,耗时:0.1749157 秒
在所有数据库中总计命中:
11,451
条
1.
Diversity selection, screening and
quantitative
structure
-
activity
relationships
of osmolyte-like additive effects on the thermal stability of a monoclonal antibody
作者:
Olubukayo-Opeyemi Oyetayo
a
;
oyetayophdhbc@gmail.com
;
Oscar Mé
;
ndez-Lucio
b
;
Andreas Bender
b
;
Hans Kiefer
a
关键词:
mAb
;
Monoclonal antibody
;
MOE
;
Molecular Operating Environment
;
MDS
;
Multi-dimensional scaling
;
QSAR
;
Quantitative
structure
&ndash
;
activity
relationship
;
DSC
;
Differential scanning calorimetry
;
DSF
;
Differential scanning fluorimetry
;
DMSO
;
Dimethyl sulfoxide
;
NaOH
;
Sodium hydroxide
;
HCl
;
Hydrochloric acid
;
LOO-CV
;
Leave-one-out cross-validation
;
PCA
;
Principal components analysis
;
PLS
;
Partial least squares
;
TMAO
;
Trimethylamine N-oxide
;
Tm
;
Melting temperature
;
TS potency
;
Thermal stabilization
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
2.
Novel anti-tumour barringenol-like triterpenoids from the husks of Xanthoceras sorbifolia Bunge and their three dimensional
quantitative
structure
activity
relationships
analysis
作者:
Da Wang
a
;
Dan Su
a
;
Bin Yu
a
;
Chuming Chen
b
;
Li Cheng
a
;
Xianzhe Li
a
;
Ronggang Xi
c
;
Huiyuan Gao
a
;
1
;
sypugaohy@163.com
;
Xiaobo Wang
c
;
wxbbenson0653@163.com
关键词:
Xanthoceras sorbifolia Bunge
;
Barrigenol-type triterpenoid
;
Antitumor activities
;
CoMFA
;
CoMSIA
;
Health benefits
刊名:Fitoterapia
出版年:2017
3.
A case study for orphaned chemicals: 4-methylcyclohexanemethanol (MCHM) and propylene glycol phenyl ether (PPH) in riverine sediment and water treatment processes
作者:
Jennifer Weidhaas
a
;
jennifer.weidhaas@mail.wvu.edu" class="auth_mail" title="E-mail the corresponding author
;
jennifer.weidhaas@utah.edu" class="auth_mail" title="E-mail the corresponding author
;
Lian-Shin Lin
b
;
Karen Buzby
b
关键词:
Activated carbon
;
Sorption
;
Desorption
;
River sediments
;
Oxidation
;
Quantitative
structure
activity
relationships
刊名:Science of the Total Environment
出版年:2017
4.
Transformation products in the water cycle and the unsolved problem of their proactive assessment: A combined in vitro/in silico approach
作者:
Jakob Menz
jakob.menz@leuphana.de
;
Anju Priya Toolaram
anjutoolaram@yahoo.com
;
Tushar Rastogi
tushar.rastogi@leuphana.de
;
Christoph Leder
cleder@leuphana.de
;
Oliver Olsson
oliver.olsson@leuphana.de
;
Klaus Kü
;
mmerer
;
klaus.kuemmerer@leuphana.de
;
Mandy Schneider
mandy.schneider@leuphana.de
关键词:
4-OH PPL
;
4-Hydroxypropranolol
;
5-OH PPL
;
5-Hydroxypropranolol
;
7-OH PPL
;
7-Hydroxypropranolol
;
AOP
;
Advanced oxidation process
;
ANOVA
;
Analysis of variance
;
DAD
;
Diode array detector
;
EDA
;
Effect-directed analysis
;
ESI-IT-MS
;
Electrospray ionization ion trap mass spectrometry
;
IR
;
Induction ratio
;
LC-MS
;
Liquid chromatography-mass spectrometry
;
LBT
;
Luminescent bacteria test
;
NPOC
;
Non-purgeable organic carbon
;
PPL
;
Propranolol
;
(Q)SAR
;
(
Quantitative
)
structure
-
activity
-
relationships
;
ThEL
;
The
刊名:Environment International
出版年:2017
5.
Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines
作者:
Daniela Rossi
a
;
&dagger
;
;
Marta Rui
a
;
Marcello Di Giacomo
a
;
Dirk Schepmann
b
;
Bernhard Wü
;
nsch
b
;
Stefania Monteleone
c
;
&dagger
;
;
Klaus R. Liedl
c
;
Simona Collina
a
;
simona.collina@unipv.it
关键词:
Sigma receptors
;
Arylalkylamine
;
Pan-affinity
;
QSAR
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
6.
Predicting anti-androgenic
activity
of bisphenols using molecular docking and
quantitative
structure
-
activity
relationships
作者:
Xianhai Yang
a
;
Huihui Liu
b
;
Qian Yang
a
;
c
;
Jining Liu
a
;
ljn@nies.org" class="auth_mail" title="E-mail the corresponding author
;
Jingwen Chen
d
;
jwchen@dlut.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Lili Shi
a
关键词:
Endocrine disrupting chemical (EDC)
;
Bisphenols
;
Anti-androgenic
activity
;
Human androgen receptor (hAR)
;
Quantitative
structure
-
activity
relationships
(QSAR)
;
Molecular docking
刊名:Chemosphere
出版年:2016
7.
Quantitative
structure
retention/
activity
relationships
of biologically relevant 4-amino-7-chloroquinoline based compounds
作者:
Sandra &Scaron
;
egan
a
;
sgaica@chem.bg.ac.rs" class="auth_mail" title="E-mail the corresponding author
;
Igor Opsenica
b
;
Mario Zlatović
b
;
Du&scaron
;
anka Milojković-Opsenica
b
;
Bogdan &Scaron
;
olaja
b
关键词:
4‑Amino-7-chloroquinoline
;
Reversed-phase thin-layer chromatography (RPTLC)
;
Lipophilicity
;
Quantitative
structure
-retention relationship (QSRR)
;
Quantitative
structure
activity
relationship (QSAR)
刊名:Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年:2016
8.
PQSAR: The membrane
quantitative
structure
-
activity
relationships
in cheminformatics
作者:
Ammar Adl
;
a
;
ammaradl@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Moustafa Zein
b
;
moustafazn@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Aboul Ella Hassanien
b
;
c
;
aboitcairo@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
关键词:
Quantitative
structure
activity
relationships
(QSAR)
;
Similarity measurements
;
Similarity searching strategy
;
P System
;
Chemical search space
;
Drug discovery
刊名:Expert Systems with Applications
出版年:2016
9.
Synthesis and in silico analysis of the
quantitative
structure
-
activity
relationship of heteroaryl-acrylonitriles as AChE inhibitors
作者:
Pedro De-la-Torre
a
;
b
;
pdelatorre@utalca.cl" class="auth_mail" title="E-mail the corresponding author
;
pldelatorrem@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Adriana V. Treuer
a
;
Margarita Gutierrez
a
;
Horacio Poblete
b
;
c
;
Jans H. Alzate-Morales
b
;
Jorge Trilleras
d
;
Luis Astudillo-Saavedra
a
;
Julio Caballero
b
;
jcaballero@utalca.cl" class="auth_mail" title="E-mail the corresponding author
;
jmcr77@yahoo.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Heteroaryl&ndash
;
acrylonitriles
;
Quantitative
structure
&ndash
;
activity
relationships
;
CoMSIA
;
Knoevenagel condensation
;
Cholinesterases
刊名:Journal of the Taiwan Institute of Chemical Engineers
出版年:2016
10.
Quantitative
relationships
between
structure
and cytotoxic
activity
of flavonoid derivatives. An application of Hirshfeld surface derived descriptors
作者:
Bogumiła Kupcewicz
a
;
kupcewicz@cm.umk.pl" class="auth_mail" title="E-mail the corresponding author
;
Magdalena Małecka
b
;
Mariusz Zapadka
a
;
Urszula Krajewska
c
;
Marek Rozalski
c
;
Elzbieta Budzisz
d
关键词:
QSAR
;
Hirshfeld surface
;
Cytotoxicity
;
Flavonoid derivatives
;
Pyrazoline
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(812)
题名(134)
关键词(148)
文摘(547)
按出版年细分(812)
2027年及以后(13)
2017年(5)
2016年(18)
2015年(3)
2014年(1)
2013年(32)
2012年(31)
2011年(30)
2010年(53)
2009年(46)
2008年(54)
2007年(46)
2006年(32)
2005年(36)
2004年(48)
2003年(47)
2002年(46)
2001年(36)
2000年(42)
2000年及以前(193)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.