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在“Elsevier电子期刊”中，命中：66条，耗时：小于0.01 秒

1.Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17

作者：Mikiro Takaishi^a ; Masayuki Ishizaki^b ; Keisuke Suzuki^c ; Takashi Isobe^b ; Takaichi Shimozato^b ; Shigetoshi Sano^a ; ^{sano.derma@kochi-u.ac.jp}

关键词：Psoriasis ; RORγt ; Antagonist ; Mouse model ; Th17

刊名：Journal of Dermatological Science

出版年：2017

2.Procyanidin B2 gallates inhibit IFN-γ and IL-17 production in T cells by suppressing T-bet and RORγt expression

作者：Sachi Tanaka^a ; ^b ; ¹ ; ^{tanakasa@shinshu-u.ac.jp} ; Kanon Furuya^a ; ¹ ; Kana Yamamoto^a ; Kazuki Yamada^a ; Mikihiro Ichikawa^c ; Manato Suda^c ; Hidefumi Makabe^c

关键词：APCs ; Antigen-presenting cells ; MHC ; Major histocompatibility complex ; TCR ; T cell receptor ; IFN ; Interferon ; IL ; Interleukin ; LPS ; Lipopolysaccharide ; PCB2 ; Procyanidin B2 ; PMA ; Phorbol 12-myristate 13-acetate ; NF ; Nuclear factor ; OG ; -O-gallate ; FITC ; Fluorescein isothiocyanate ; PI ; Propidium iodide ; PE ; Phycoerythrin ; BFA ; Brefeldin A ; PI3K ; Phosphatidylinositol 3-kinase ; S6-K ; S6 kinase

刊名：International Immunopharmacology

出版年：2017

作者：Maria Liljevald^a ; ^{maria.liljevald@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Maria Rehnberg^b ; Magnus Sö ; derberg^a ; Marie Ramnegå ; rd^b ; Jenny Bö ; rjesson^c ; Donatella Luciani^b ; Nina Krutrö ; k^b ; Lena Brä ; ndé ; n^a ; Camilla Johansson^a ; Xiufeng Xu^c ; Mikael Bjursell^c ; Anna-Karin Sjö ; gren^a ; Jorrit Hornberg^a ; Ulf Andersson^a ; David Keeling^b ; Johan Jirholt^b

关键词：NHR ; RORγ ; RORγt ; Rorc ; Th17 cells ; Adult induced knockout mouse model ; Lymphoblastic lymphoma

刊名：Autoimmunity Reviews

出版年：2016

4.Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model

作者：Azumi Ueyama^a ; ^{azumi.ueyama@shionogi.co.jp} ; Chihiro Imura^a ; Yasuyuki Fusamae^a ; Kenichiro Tsujii^a ; Yoko Furue^b ; Miwa Aoki^a ; Minoru Suzuki^a ; Tomohiko Okuda^a ; Itsuki Oshima^a ; Kiyoshi Yasui^c ; Michitaka Shichijo^a ; Mina Yamamoto^a

关键词：ILC ; innate lymphoid cells ; MAIT cell ; mucosal associated invariant T cell ; IMQ ; imiquimod ; TLR7 ; Toll-like receptor ; TPA ; tumor promoter 12-O-tetradecanoylphorbol-13-acetate ; DN αβ T cells ; αβ-TCR+ CD4CD8 double negative T cells ; RORγt ; retinoic acid-related orphan receptor gamma t ; CCR6 ; CC chemokine receptor 6 ; SLE ; systematic lupus erythematosus ; ALPS ; autoimmune lymphoproliferative syndrome ; PMA ; phorbol 12-myristate 13-acetate ; LN ; lymph node ; NK T cell ; natural killer T cell ; DC ; dendriti

刊名：Journal of Dermatological Science

出版年：2017

5.The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

作者：Tae Gyu Oh^a ; Shu-Ching M. Wang^a ; Bipul R. Acharya^a ; Joel M. Goode^a ; J. Dinny Graham^b ; Christine L. Clarke^b ; Alpha S. Yap^a ; George E.O. Muscat^a ; ^{g.muscat@uq.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Nuclear receptor ; RORγ (RORC ; RORgamma) ; Breast cancer ; Carcinogenesis ; Metastasis ; RNA-seq ; EMT (epithelial&ndash ; mesenchymal transition) ; TGF-β (TGF-beta) ; Stemness ; MaSC (mammary stem cell) ; DNA repair

刊名：EBioMedicine

出版年：2016

6.Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity

作者：Yanxia Guo¹ ; ⁷ ; Kenzie D. MacIsaac² ; ⁸ ; Yi Chen¹ ; Richard J. Miller² ; Renu Jain¹ ; Barbara Joyce-Shaikh¹ ; Heidi Ferguson² ; I-Ming Wang³ ; Razvan Cristescu¹ ; John Mudgett⁴ ; Laura Engstrom² ; Kyle J. Piers² ; Gretchen A. Baltus² ; Kenneth Barr² ; Hongjun Zhang² ; Huseyin Mehmet² ; Laxminarayan G. Hegde² ; Xiao Hu⁵ ; Laura L. Carter⁵ ; Thomas D. Aicher⁵ ; Gary Glick⁵ ; Dennis Zaller² ; Abbas Hawwari⁶ ; Craig C. Correll² ; Dallas C. Jones² ; ⁹ ; Daniel J. Cua¹ ; ¹⁰ ; ^{daniel.cua@merck.com}

关键词：RORγT ; small-molecule antagonist ; thymopoiesis ; T cell repertoire ; autoimmunity ; experimental autoimmune encephalomyelitis ; experimental psoriasis

刊名：Cell Reports

出版年：2016

7.Discovery of biaryls as RORγ inverse agonists by using structure-based design

作者：Istvan J. Enyedy^a ; ^{istvan.enyedy@biogen.com" class="auth_mail" title="E-mail the corresponding author} ; Noel A. Powell^a ; Justin Caravella^a ; Kurt van Vloten^a ; Jianhua Chao^a ; Daliya Banerjee^a ; Douglas Marcotte^a ; Laura Silvian^a ; Andres McKenzie^a ; Victor Sukbong Hong^b ; Jason D. Fontenot^a

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.PP - IMMUNOEXPRESSION OF IL-17, IL-23 AND RORγT IN THE PATHOGENESIS OF PERIODONTAL DISEASE

刊名：Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

出版年：2017

9.STA-21, a STAT-3 inhibitor, attenuates the development and progression of inflammation in collagen antibody-induced arthritis

作者：Sheikh Fayaz Ahmad^a ; ^{s_fayazahmad@yahoo.com} ; ^{fashaikh@ksu.edu.sa} ; Mushtaq Ahmad Ansari^a ; Ahmed Nadeem^a ; Khairy M.A. Zoheir^a ; ^b ; Saleh A. Bakheet^a ; Abdulaziz M.S. Alsaad^a ; Othman A. Al-Shabanah^a ; Sabry M. Attia^a ; ^c

关键词：5-Clone cocktail of monoclonal anti-type II collagen antibodies ; STA-21 ; Transcription factors ; Regulatory T cells ; Cytokines

刊名：Immunobiology

出版年：2017

10.Th17 master transcription factors RORα and RORγ regulate the expression of IL-17C, IL-17D and IL-17F in Cynoglossus semilaevis

作者：Heng Chi^a ; ^b ; Jarl Bø ; gwald^c ; Roy Ambli Dalmo^c ; Wenjie Zhang^d ; Yong-hua Hu^a ; ^b ; ^{huyonghua@qdio.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：RORα ; RORγ ; IL-17 ; Promoter activity ; Cynoglossus semilaevis

刊名：Developmental & Comparative Immunology

出版年：2016

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