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在“Elsevier电子期刊”中，命中：6条，耗时：0.0109954 秒

1.Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study

作者：Lydia Aschauer^a ; Alice Limonciel^a ; Anja Wilmes^a ; Sven Stanzel^b ; Annette Kopp-Schneider^b ; Philip Hewitt^c ; Arno Lukas^d ; Martin O. Leonard^e ; Walter Pfaller^a ; Paul Jennings^a ; ^{paul.jennings@i-med.ac.at" class="auth_mail" title="E-mail the corresponding author} ; ^{paul.other@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Proximal tubule ; RPTEC/TERT1 ; Nephrotoxin ; Transcriptomics ; Stress response

刊名：Toxicology in Vitro

出版年：2015

2.Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1

作者：Lydia Aschauer^a ; Giada Carta^a ; Nadine Vogelsang^b ; Eberhard Schlatter^b ; Paul Jennings^a ; ^{Paul.Jennings@i-med.ac.at" class="auth_mail" title="E-mail the corresponding author} ; ^{paul.other@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：4-Di-1-ASP ; 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide ; CsA ; Cyclosporine A ; primary hPT ; human primary proximal tubule cells ; MATE ; multidrug and toxin extrusion proteins ; OAT ; organic anion transporter ; OATP ; organic anion polypeptide transporters ; OCT ; organic cation transporter ; PBPK ; physiologically based pharmacokinetic modelling ; RFU ; raw fluorescence unit ; TEER ; transepithelial electrical resistance

刊名：Toxicology in Vitro

出版年：2015

3.Biokinetics in repeated-dosing in vitro drug toxicity studies

作者：Nynke I. Kramer^a ; ^{N.I.Kramer@uu.nl" class="auth_mail" title="E-mail the corresponding author} ; Emma Di Consiglio^b ; Bas J. Blaauboer^a ; Emanuela Testai^b

关键词：In vitro ; Repeated dosing ; Quantitative in vitro&ndash ; in vivo extrapolation ; Biokinetics ; Predict-IV

刊名：Toxicology in Vitro

出版年：2015

4.Optimization of a quantitative PCR based method for plasmid copy number determination in human cell lines

作者：Lukas Fliedl^a ; ¹ ; Florian Kast^a ; ¹ ; Johannes Grillari^a ; ^b ; Matthias Wieser^a ; Regina Grillari-Voglauer^a ; ^b ; ^{regina.grillari@boku.ac.at" class="auth_mail" title="E-mail the corresponding author}

刊名：New Biotechnology

出版年：2015

5.Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress

作者：Anja Wilmes^a ; ¹ ; Alice Limonciel^a ; ¹ ; Lydia Aschauer^a ; ¹ ; Konrad Moenks^b ; ¹ ; Chris Bielow^c ; Martin O. Leonard^d ; Jeremy Hamon^e ; ^f ; Donatella Carpi^g ; Silke Ruzek^h ; Andreas Handler^h ; Olga Schmalⁱ ; Karin Herrgenⁱ ; Patricia Bellwonⁱ ; Christof Burekⁱ ; Germaine L. Truisi^j ; ^m ; Philip Hewitt^j ; Emma Di Consiglio^k ; Emanuela Testai^k ; Bas J. Blaauboer^l ; Claude Guillou^g ; Christian G. Huber^h ; Arno Lukas^b ; Walter Pfaller^a ; Stefan O. Mueller^j ; ^m ; Frederic Y. Bois^e ; ^f ; Wolfgang Dekantⁱ ; Paul Jennings^a ; ¹ ; ^{paul.jennings@i-med.ac.at} ; ^{paul.other@gmail.com}

关键词：Cyclosporine A ; Integrated omics ; ATF4 ; Nrf2 ; Unfolded protein response ; Cyclophilin

刊名：Journal of Proteomics

出版年：2013

6.Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

作者：Alice ; Limonciel^a ; ; ¹ ; Lydia ; Aschauer^a ; ; ¹ ; Anja ; Wilmes^a ; ; ¹ ; Sinikka ; Prajczer^a ; Martin O. ; Leonard^b ; Walter ; Pfaller^a ; Paul ; Jennings^a ; ; ^{paul.jennings@i-med.ac.at} ; ; ^{paul.other@gmail.com}

关键词：Lactate ; Oxidative stress ; HepaRG ; RPTEC/TERT1 ; BALB-3T3 ; Cell culture ; Toxicity ; Cell stress

刊名：Toxicology in Vitro

出版年：2011

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