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内部出版物
在“
Elsevier电子期刊
”中,
命中:
11,048
条,耗时:小于0.01 秒
1.
Green synthesis of novel spiro[indoline-3,4′-py
raz
olo[3,4-b]pyridine]-2,3′(7′
H)- dione, spiro[indeno[1,2-b]py
raz
olo[4,3-e]pyridine-4,3′-indoline]-2′,3-dione, and spiro[benzo [h]py
raz
olo[3,4-b]quinoline-7,3′-indoline]-2′,8(5H)-dione derivatives in aqueous medium
作者:
Zhansheng Wang
;
Lingli Gao
;
Zhongyun Xu
;
Zhi Ling
;
Yaqi Qin
;
Liangce Rong
;
lcrong@jsnu.edu.cn
;
Shu-Jiang Tu
关键词:
Py
raz
olo[3
;
4-b]pyridine
;
Py
raz
olo[4
;
3-e]pyridine
;
Py
raz
olo[3
;
4-b]quinoline
;
Aqueous medium
;
Green synthesis
刊名:Tetrahedron
出版年:2017
2.
An insight on synthetic and medicinal aspects of py
raz
olo[1,5-a]pyrimidine scaffold
作者:
Srinivasulu Cherukupalli
;
Rajshekhar Karpoormath
;
karpoormath@ukzn.ac.za
;
Balakumar Chandrasekaran
;
Girish. A. Hampannavar
;
Neeta Thapliyal
;
Venkata Narayana Palakollu
关键词:
Py
raz
olo[1
;
5-a]pyrimidine
;
Anti-cancer agents
;
Anti-infectious agents
;
CNS agents
;
Anti-inflammatory agents
;
Radiopharmaceuticals
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Design, synthesis and cytotoxicity studies of novel py
raz
olo[1, 5-a]pyridine derivatives
作者:
Chitrakar Ravi
a
;
1
;
Arem Qayum
b
;
1
;
Darapaneni Chandra Mohan
a
;
Shashank K. Singh
b
;
sksingh@iiim.ac.in
;
Subbarayappa Adimurthy
a
;
adimurthy@csmcri.org
关键词:
Py
raz
olo[1
;
5&ndash
;
a]pyridines
;
Cytotoxicity
;
MCF-7 cells
;
Growth inhibition
;
SRB assay
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new py
raz
olo[1,5-a]pyrimidines
作者:
Michaela Hylsová
;
a
;
1
;
Benoit Carbain
a
;
f
;
1
;
Jindřich Fanfrlí
;
k
b
;
1
;
Lenka Musilová
;
a
;
Susanta Haldar
b
;
c
;
Cemal Kö
;
prü
;
lü
;
oğlu
b
;
c
;
Haresh Ajani
b
;
c
;
Pathik S. Brahmkshatriya
b
;
Radek Jorda
d
;
Vladimí
;
r Kry&scaron
;
tof
d
;
Pavel Hobza
b
;
c
;
Aude Echalier
e
;
2
;
Kamil Paruch
a
;
f
;
paruch@chemi.muni.cz
;
Martin Lep&scaron
;
í
;
k
b
;
lepsik@uochb.cas.cz
关键词:
Cyclin-dependent kinase 2
;
ATP-competitive type I inhibitors
;
Py
raz
olo[1
;
5-a]pyrimidine
;
Quantum mechanical scoring
;
Protein-ligand binding
;
Molecular dynamics
;
Water thermodynamics
;
X-ray crystal structure
刊名:European Journal of Medicinal Chemistry
出版年:2017
5.
Synthesis and antitumor activity of some new py
raz
olo[1,5-a]pyrimidines
作者:
Ashraf S. Hassan
a
;
ashraf_salmoon@yahoo.com
;
Mohamed F. Mady
b
;
c
;
Hanem M. Awad
d
;
Taghrid S. Hafez
a
关键词:
5-Amino-1H-py
raz
ole
;
Py
raz
olo[1
;
5-a]pyrimidine
;
Schiff bases
;
MTT assay
;
Anticancer activity
;
Structure activity relationship
刊名:Chinese Chemical Letters
出版年:2017
6.
Py
raz
olo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of anti-tubercular activity
作者:
Xiaoyun Lu
a
;
b
;
1
;
luxy2016@jnu.edu.cn
;
Jian Tang
b
;
c
;
1
;
Shengyang Cui
b
;
c
;
Baojie Wan
d
;
Scott G. Franzblauc
d
;
Tianyu Zhang
b
;
Xiantao Zhang
e
;
Ke Ding
a
;
b
关键词:
Anti-tubercular
;
Hybrid
;
Mtb
;
Py
raz
olo[1
;
5-a]pyridine-3-carboxamide
刊名:European Journal of Medicinal Chemistry
出版年:2017
7.
Evaluation of 7-arylaminopy
raz
olo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors
作者:
Luí
;
s Felipe S.P. Azeredo
a
;
b
;
Julia P. Coutinho
c
;
d
;
Valquiria A.P. Jabor
e
;
Patricia R. Feliciano
e
;
Maria Cristina Nonato
e
;
Carlos R. Kaiser
b
;
Carla Maria S. Menezes
a
;
Amanda S.O. Hammes
f
;
Ernesto Raul Caffarena
f
;
Lucas V.B. Hoelz
a
;
Nicolli B. de Souza
c
;
Glaé
;
cia A.N. Pereira
c
;
Isabela P. Cerá
;
volo
c
;
Antoniana U. Krettli
c
;
d
;
Nubia Boechat
a
;
b
;
boechat@far.fiocruz.br
关键词:
Malaria
;
P. falciparum
;
Py
raz
olo[1
;
5-a]pyrimidine
;
Dihydroorotate dehydrogenase (DHODH)
;
Molecular docking
刊名:European Journal of Medicinal Chemistry
出版年:2017
8.
Novel py
raz
olo[3,4-d]pyrimidine with 4-(1H-benzimidazol-2-yl)-phenylamine as broad spectrum anticancer agents: Synthesis, cell based assay, topoisomerase inhibition, DNA intercalation and bovine serum albumin studies
作者:
Prinka Singla
a
;
Vijay Luxami
a
;
vluxami@thapar.edu
;
Raja Singh
b
;
Vibha Tandon
b
;
Kamaldeep Paul
a
;
kpaul@thapar.edu
关键词:
Py
raz
olo[3
;
4-d]pyrimidine
;
Benzimidazole
;
Antitumor activity
;
ct-DNA
;
Bovine serum albumin
刊名:European Journal of Medicinal Chemistry
出版年:2017
9.
Derivatives of the py
raz
olo[1,5-a]pyrimidine acetamide DPA-713 as translocator protein (TSPO) ligands and pro-apoptotic agents in human glioblastoma
作者:
Eryn L Werry
a
;
1
;
Victoria A. King
b
;
1
;
Melissa L Barron
a
;
Samuel D. Banister
c
;
Renee Sokias
c
;
Michael Kassiou
c
;
michael.kassiou@sydney.edu.au
关键词:
BrdU
;
5-bromo-2&prime
;
-deoxyuridine
;
DMEM/F12
;
Dulbecco's modified eagle's medium
;
Ham's nutrient mixture F-12
;
DMSO
;
dimethyl sulfoxide
;
EDTA
;
ethylenediaminetetraacetic acid
;
LLE
;
lipophilic ligand efficiency
;
MEM
;
minimum essential medium
;
PET
;
positron emission tomography
;
SPECT
;
single-photon emission computed tomography
;
TSPO
;
translocator protein
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
10.
Design, synthesis, and biological evaluation of novel 1-oxo-1,2,3,4-tetrahydropy
raz
ino[1,2-a]indole-3-carboxamide analogs in MCF-7 and MDA-MB-468 breast cancer cell lines
作者:
Ye Jin Kim
a
;
c
;
Jae Sung Pyo
a
;
c
;
Young-Suk Jung
b
;
youngjung@pusan.ac.kr
;
Jae-Hwan Kwak
a
;
jhkwak@ks.ac.kr
关键词:
Anti-breast cancer activity
;
Py
raz
inoindolone scaffold
;
Gefitinib-resistant TNBC
;
Inhibition of p-Akt
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
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