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CNKI学位论文(78)
知网期刊论文(11)
在“
Elsevier电子期刊
”中,
命中:
11
条,耗时:小于0.01 秒
在所有数据库中总计命中:
89
条
1.
[2.2.1]-Bicyclic sulta
m
s as potent androgen receptor antagonists
作者:
Weifang Shan
;
weifang.shan@b
m
s.co
m
" class="auth_
m
ail" title="E-
m
ail the corresponding author
;
Aaron Balog
;
Andrew Nation
;
Xiao Zhu
;
Jing Chen
;
M
ary Ellen Cvijic
;
Jieping Geng
;
Cheryl A. Rizzo
;
Tho
m
as Spires Jr.
;
Ricardo
M
.
Attar
;
M
ary Ober
m
eier
;
Sarah Traeger
;
Jun Dai
;
Yingru Zhang
;
M
ichael Galella
;
George Trainor
;
Gregory D. Vite
;
Ashviniku
m
ar V. Gavai
关键词:
Cancer
;
Nuclear hor
m
one receptor
;
Androgen receptor antagonist
;
Phar
m
acokinetics and phar
m
acodyna
m
ics
刊名:Bioorganic &
M
edicinal Che
m
istry Letters
出版年:2016
2.
M
odulation of cofilin phosphorylation by inhibition of the Li
m
fa
m
ily kinases
作者:
Liqi He
;
Steven P. Seitz
;
George L. Trainor
;
David Tortolani
;
Wayne Vaccaro
;
M
ichael Poss
;
Christine
M
. Tarby
;
John S. Tokarski
;
Becky Penhallow
;
Chen-Yi Hung
;
Ricardo
Attar
;
Tai-An Lin
关键词:
LI
M
K1
;
LI
M
K2
;
Cofilin phosphorylation
;
Actin cytoskeleton
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2012
3.
Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0
2,6
]undec-4-yl]-2-trifluoro
m
ethyl-benzonitriles as androgen receptor antagonists
作者:
Hai-Yun Xiao
;
Aaron Balog
;
Ricardo
M
.
Attar
;
David Fairfax
;
Linda B. Fle
m
ing
;
Christian L. Holst
;
Gregory S.
M
artin
;
Lana
M
. Rossiter
;
Jing Chen
;
M
ary-Ellen Cvjic
;
Janet Dell-John
;
Jieping Geng
;
M
arco
关键词:
Androgen receptor
;
Prostate cancer
;
Antagonist
;
Diazatricycloundecane
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2010
4.
Balancing oral exposure with Cyp3A4 inhibition in benzi
m
idazole-based IGF-IR inhibitors
作者:
Kurt Zi
mm
er
m
ann
;
M
ark D. Witt
m
an
;
M
ark G. Saulnier
;
Upender Velaparthi
;
David R. Langley
;
Xiaopeng Sang
;
David Frennesson
;
Joan Carboni
;
Aixin Li
;
Ann Greer
;
M
arco Gottardis
;
Ricardo
M
.
Attar
;
Zheng Y
关键词:
IGF-IR inhibitor
;
Cyp3A4
;
Cytochro
m
e 3A4
;
Oral exposure
;
Oral bioavailability
;
M
alonate
;
M
ethyl anion synthon
;
S
N
Ar reaction
;
Decarboxylation
;
p
K
a
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2008
5.
Identification and opti
m
ization of a novel series of [2.2.1]-oxabicyclo i
m
ide-based androgen receptor antagonists
作者:
M
ark E. Salvati
;
Aaron Balog
;
Weifang Shan
;
Richard Ra
m
pulla
;
Soren Giese
;
To
m
Mitt
;
Joseph A. Furch
;
Gregory D. Vite
;
Ricardo
M
.
Attar
;
M
aria Jure-Kunkel
;
Jieping Geng
;
Cheryl A. Rizzo
;
M
arco M. Gott
关键词:
Androgen receptor
;
Prostate cancer
;
AR antagonist
;
CWR22R
;
[2.2.1]-Oxabicyclo
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2008
6.
Novel 1H-(benzi
m
idazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase
作者:
M
ark D. Witt
m
an
;
Balu Balasubra
m
anian
;
Karen Stoffan
;
Upender Velaparthi
;
Pieying Liu
;
Subra
m
ania
m
Krishnanathan
;
Joan Carboni
;
Aixin Li
;
Ann Greer
;
Ricardo
Attar
;
et al.
关键词:
Insulin-like growth factor
;
IGF-1R
;
Inhibitor
;
Kinase
;
ATP co
m
petitive
;
Benzi
m
idazole
;
4-A
m
inopyridone
;
Substituted 2-hydroxy-2-phenyl-a
m
inoethanol
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2007
7.
Discovery and initial SAR of 3-(1H-benzo[d]i
m
idazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)
作者:
Upender Velaparthi
;
M
ark Witt
m
an
;
Peiying Liu
;
Karen Stoffan
;
Kurt Zi
mm
er
m
ann
;
Xiaopeng Sang
;
Joan Carboni
;
Aixin Li
;
Ricardo
Attar
;
M
arco Gottardis
;
et al.
关键词:
Insulin-like growth factor-1 receptor
;
Tyrosine kinase
;
Benzi
m
idazole
;
Pyridone
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2007
8.
I
m
idazole
m
oiety replace
m
ents in the 3-(1H-benzo[d]i
m
idazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to i
m
prove cytochro
m
e P450 profile
作者:
Upender Velaparthi
;
Peiying Liu
;
Balu Balasubra
m
anian
;
Joan Carboni
;
Ricardo
Attar
;
M
arco Gottardis
;
Aixin Li
;
Ann Greer
;
M
ary Zoeckler
;
M
ark D. Witt
m
an
;
et al.
关键词:
Insulin-like growth factor-1 receptor
;
IGF-1R
;
Tyrosine kinase
;
Benzi
m
idazole
;
I
m
idazole
;
CYP450 inhibition
;
I
m
idazoline
;
Pyridone
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2007
9.
Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists
作者:
Salvati
;
M
ark E.
;
Balog
;
Aaron
;
Shan
;
Weifang
;
Wei
;
Donna D.
;
Pickering
;
Dacia
;
Attar
;
Ricardo
M
.
;
et. al.
关键词:
Androgen receptor
;
Antagonists
;
Crystal structure
;
Prostate cancer
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2005
10.
Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus
作者:
Salvati
;
M
ark E.
;
Balog
;
Aaron
;
Wei
;
Donna D.
;
Pickering
;
Dacia
;
Attar
;
Ricardo
M
.
;
Geng
;
Jieping
;
et. al.
关键词:
Androgen receptor
;
Prostate cancer
;
Antagonist
刊名:Bioorganic and
M
edicinal Che
m
istry Letters
出版年:2005
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