设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
CNKI学位论文(264)
知网期刊论文(67)
在“
Elsevier电子期刊
”中,
命中:
47
条,耗时:0.1019522 秒
在所有数据库中总计命中:
331
条
1.
Novel small molecule inhibitors targeting the ¡°s
w
itch region¡± of bacterial RNAP: Structure-based optimization of a virtual screening hit
作者:
J. Henning Sahner
;
Matthias Groh
;
Matthias Negri
;
J?rg Haupenthal
;
Rolf
W
.
Hartmann
关键词:
Bacterial RNAP inhibitor
;
S
w
itch region
;
Myxopyronin
;
Ureidothiophene carboxylic acid
;
QSAR
;
Antibacterial agent
刊名:European Journal of Medicinal Chemistry
出版年:2013
2.
Development and validation of a UHPLC-MS/MS procedure for quantification of the Pseudomonas Quinolone Signal in bacterial culture after acetylation for characterization of ne
w
quorum sensing inhibitors
作者:
Christine K. Maurer
;
Anke Steinbach
;
Rolf
W
.
Hartmann
关键词:
UHPLC&ndash
;
MS/MS
;
Acetylation
;
Pseudomonas Quinolone Signal
;
Quorum sensing inhibitors
;
T
w
o-point calibration
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2013
3.
Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-gro
w
th inhibitors in tumor cells
w
ith
w
ild type p53
作者:
Mohammad Abdel-Halim
;
Adam B. Keeton
;
Evrim Gurpinar
;
Bernard D. Gary
;
Simon M. Vogel
;
Matthias Engel
;
Gary A. Piazza
;
Frank M. Boeckler
;
Rolf
W
.
Hartmann
;
Ashraf H. Abadi
关键词:
Pyrazoline
;
Anticancer
;
p53
刊名:Bioorganic and Medicinal Chemistry
出版年:1 December, 2013
4.
Unexpected results of a S
NAr
-reaction. A novel synthetic approach to 1-arylthio-2-naphthols
作者:
Cornelia M. Grombein
;
Qingzhong Hu
;
Ralf Heim
;
Volker Huch
;
Rolf
W
.
Hartmann
关键词:
1-Arylthio-2-naphthol
;
SNAr-reaction
;
Triflate
;
Thiophenol
刊名:Tetrahedron Letters
出版年:27 November, 2013
5.
Novel N-methylsulfonamide and retro-N-methylsulfonamide derivatives as 17尾-hydroxysteroid dehydrogenase type 2 (17尾-HSD2) inhibitors
w
ith good ADME-related physicochemical parameters
作者:
Enrico Perspicace
;
Annalaura Giorgio
;
Angelo Carotti
;
S
;
rine Marchais-Ober
w
inkler
;
Rolf
W
.
Hartmann
关键词:
17尾-Hydroxysteroid dehydrogenase type 2
;
Enzyme inhibition
;
Osteoporosis
;
N-Methylsulfonamide derivatives
;
Retro-N-methylsulfonamide derivatives
;
Structure&ndash
;
activity relationship
;
Structure&ndash
;
property relationship
;
ADME properties
;
pKa
;
Log P
;
Aqueous solubility
刊名:European Journal of Medicinal Chemistry
出版年:November, 2013
6.
Corrigendum to ¡°Synthesis and aromatase inhibitory activity of some ne
w
16E-arylidenosteroids¡± [Bioorg. Chem. 45 (2012) 36-40]
作者:
Ranju Bansal
;
Sridhar Thota
;
Nalin Karkra
;
Maninder Minu
;
Christina Zimmer
;
Rolf
W
.
Hartmann
刊名:Bioorganic Chemistry
出版年:2013
7.
Catalytic enzyme activity on a biosensor chip: Combination of surface plasmon resonance and mass spectrometry
作者:
Claudia Henn
;
Stefan Boettcher
;
Anke Steinbach
;
Rolf
W
.
Hartmann
关键词:
Surface plasmon resonance
;
UHPLC&ndash
;
MS2
;
Catalytic activity
刊名:Analytical Biochemistry
出版年:2012
8.
Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa
作者:
Cenbin Lu
1
;
Benjamin Kirsch
1
;
Christina Zimmer
1
;
Johannes
;
C. de
;
Jong
1
;
Claudia Henn
1
;
Christine
;
K. Maurer
1
;
Mathias Mü
;
sken
2
;
Susanne Hä
;
ussler
2
;
3
;
Anke Steinbach
1
;
anke.steinbach@helmholtz-hzi.de
;
Rolf
;
W
.
Hartmann
1
;
4
;
rolf
.
hartmann
@helmholtz-hzi.de
刊名:Chemistry & Biology
出版年:2012
9.
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2)
作者:
Christina Zimmer
;
Marieke Hafner
;
Michael Zender
;
Dominic Ammann
;
Rolf
W
.
Hartmann
;
Carsten A. Vock
关键词:
CYP11B2
;
Aldosterone synthase
;
Selective inhibition
;
Metyrapone
;
Aldosterone
;
Congestive heart failure
;
Myocardial fibrosis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2011
10.
Influence of amantadine on CD81 expression on lymphocytes in chronic hepatitis C
作者:
Martin-
W
alter Welker
;
Michael von
W
agner
;
Dana Ochs
;
Vincent Zimmer
;
W
olf Peter Hofmann
;
Albrecht Piiper
;
Rolf
W
.
Hartmann
;
Eva Herrmann
;
Stefan Zeuzem
;
Bernd Kronenberger
关键词:
Amantadine
;
CD81
;
HCV
;
PBMC
刊名:Digestive and Liver Disease
出版年:2010
1
2
3
4
5
按检索点细分(47)
作者(46)
文摘(1)
按出版年细分(47)
2027年及以后(2)
2013年(3)
2012年(2)
2011年(1)
2010年(3)
2009年(8)
2008年(5)
2007年(1)
2006年(2)
2005年(1)
2004年(2)
2003年(3)
2002年(2)
2001年(1)
2000年(3)
2000年及以前(8)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.