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在“Elsevier电子期刊”中，命中：46条，耗时：小于0.01 秒

在所有数据库中总计命中：119条

1.Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase

作者：David L. Ebenezer^a ; Panfeng Fu^b ; Vidyani Suryadevara^c ; Yutong Zhao^d ; Viswanathan Natarajan^b ; ^e ; ^{visnatar@uic.edu}

关键词：Acute lung injury ; S1P signaling ; Histone acetylation ; S1P lyase ; Sphingosine kinases ; Hexadecenal ; Histone deacetylases

刊名：Advances in Biological Regulation

出版年：2017

2.Creation of a S1P Lyase bacterial surrogate for structure-based drug design

作者：Maria A. Argiriadi^a ; ^{maria.argiriadi@abbvie.com" class="auth_mail" title="E-mail the corresponding author} ; David Banach^b ; Elzbieta Radziejewska^b ; Susan Marchie^b ; Jennifer DiMauro^b ; Jurgen Dinges^c ; Eric Dominguez^b ; Charles Hutchins^c ; Russell A. Judge^c ; Kara Queeney^b ; Grier Wallace^a ; Christopher M. Harris^b

关键词：S1P Lyase ; Site-directed mutagenesis ; Homology modeling ; Crystal structure

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Bacterial versus human sphingosine-1-phosphate lyase (S1PL) in the design of potential S1PL inhibitors

作者：Pol Sanllehí ; ^a ; ^b ; José ; -Luis Abad^a ; Josefina Casas^a ; Jordi Bujons^c ; ^{jordi.bujons@iqac.csic.es" class="auth_mail" title="E-mail the corresponding author} ; Antonio Delgado^a ; ^b ; ^{delgado@rubam.net" class="auth_mail" title="E-mail the corresponding author}

关键词：Sphingolipids ; Lyase ; Inhibitors ; Design ; Docking

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.A facile stable-isotope dilution method for determination of sphingosine phosphate lyase activity

作者：Jung H. Suh ; Abeer Eltanawy ; Apoorva Rangan ; Julie D. Saba ; ^{jsaba@chori.org" class="auth_mail" title="E-mail the corresponding author}

关键词：HQ ; 2-hydrazinoquinoline ; S1P ; sphingosine-1-phosphate ; LC/MS ; liquid chromatography/mass spectrometry ; C17-S1P ; sphingosine-1-phosphate ; MRM ; multiple reaction monitoring ; CE ; collision energy ; CV ; cone votage ; DNPH ; 2 ; 4-dinitrophenylhydrazine ; DAIH ; 2-diphenylacetyl-1 ; 3-indandion-1-hydrazone ; SPL ; sphingosine phosphate lyase

刊名：Chemistry and Physics of Lipids

出版年：2016

5.A systematic methodology for large scale compound screening: A case study on the discovery of novel S1PL inhibitors

作者：Utku Deniz ; Elif Ozkirimli ; Kutlu O. Ulgen ; ^{ulgenk@boun.edu.tr" class="auth_mail" title="E-mail the corresponding author}

关键词：Sphingosine 1-phosphate lyase (S1PL) ; Multiple sclerosis (MS) disease ; Virtual screening ; Efficiency indices (BEI & LLE) ; Substructure search

刊名：Journal of Molecular Graphics and Modelling

出版年：2016

6.Studies on the inhibition of sphingosine-1-phosphate lyase by stabilized reaction intermediates and stereodefined azido phosphates

作者：Pol Sanllehí ; ^a ; ^c ; José ; -Luí ; s Abad^a ; Jordi Bujons^b ; Josefina Casas^a ; ; Antonio Delgado^a ; ^c ; ^{delgado@rubam.net" class="auth_mail" title="E-mail the corresponding author}

关键词：Sphingolipids ; Enzyme inhibitor ; Sphingosine lyase ; Synthesis ; Stereocontrolled

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors

作者：Jurgen Dinges^a ; ; Christopher M. Harris^b ; Grier A. Wallace^c ; Maria A. Argiriadi^c ; Kara L. Queeney^b ; Denise C. Perron^b ; Eric Dominguez^b ; Tegest Kebede^b ; Kelly E. Desino^a ; Hetal Patel^a ; Anil Vasudevan^a

关键词：Sphingosine 1-phosphate lyase ; Hit-to-lead ; Inhibitor ; Parallel synthesis ; Structure-based design

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Inhibitors of sphingosine-1-phosphate metabolism (sphingosine kinases and sphingosine-1-phosphate lyase)

作者：Pol Sanllehí ; ^a ; ^b ; José ; -Luis Abad^a ; Josefina Casas^a ; Antonio Delgado^a ; ^b ; ^{delgado@rubam.net" class="auth_mail" title="E-mail the corresponding author}

关键词：3-kdhSo ; 3-ketodihydrosphingosine ; aSMase ; acid sphingomyelinase ; aCDase ; acid ceramidase ; C1P ; ceramide-1-phosphate ; Cer ; ceramide ; CerK ; ceramide kinase ; CerS ; ceramide synthases ; CerT ; ceramide transporter protein ; cPLA2a ; cytosolic phospholipase A2 ; Des1 ; dhCer desaturase ; dhCer ; dihydroceramide ; dhSo ; dihydrosphingosine (sphinganine) ; ER ; endoplasmic reticulum ; FAPP2 ; four-phosphate adaptor protein ; GC ; glucosyl ceramide ; GCS ; glucosyl ceramide synthase ; GSL ; complex glycosphingolipids ; HDL

刊名：Chemistry and Physics of Lipids

出版年：2016

9.Role of Sphingolipids in Infant Gut Health and Immunity

作者：Å ; ke Nilsson ; MD ; PhD ; ^{ake.nilsson@med.lu.se" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; Colorectal cancer ; DSS ; Dextran sulphate sodium ; IBD ; Inflammatory bowel disease ; KO ; Knockout ; MFGM ; Milk fat globule membrane ; NC ; Neutral ceramidase ; NEC ; Necrotizing enterocolitis ; NPP7 ; Nucleotide phosphodiesterase pyrophosphatase 7 ; PAF ; Platelet activating factor ; PC ; Phosphatidylcholine ; PL ; Glycerophospholipids ; S1P ; Sphingosine-1-phosphate ; SL ; Sphingolipids ; SM ; Sphingomyelin

刊名：The Journal of Pediatrics

出版年：2016

10.Sphingosine-1-phosphate (S1P) displays sustained S1P₁ receptor agonism and signaling through S1P lyase-dependent receptor recycling

作者：John Gatfield ; ^{john.gatfield@actelion.com" class="auth_mail} ; Lucile Monnier ; Rolf Studer ; Martin H. Bolli ; Beat Steiner ; Oliver Nayler

关键词：BSA ; bovine serum albumin ; CHO ; Chinese hamster ovary ; CRC ; concentration&ndash ; response curve ; EC50 ; half maximimal excitatory concentration ; Emax ; maximal efficacy versus a defined control ; FBS ; fetal bovine serum ; GPCR ; G protein coupled receptor ; GRK ; GPCR related kinase ; HUVEC ; human umbilical vein endothelial cells ; PBS ; phosphate buffered saline ; S1P ; sphingosine-1-phosphate ; S1PR ; sphingosine-1-phosphate receptor ; SPL ; S1P lyase ; SD ; arithmetic standard deviation ; 蟽g ; geometric standard

刊名：Cellular Signalling

出版年：July 2014

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