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内部出版物
CNKI学位论文(35)
知网期刊论文(3)
在“
Elsevier电子期刊
”中,
命中:
4
条,耗时:小于0.01 秒
在所有数据库中总计命中:
38
条
1.
Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation
作者:
Graciela B. Arhancet
;
graciela.arhancet@novusint.com
;
Daniel P. Walker
;
Sue Metz
;
Yvette M. Fobian
;
Steven
E.
Heasley
;
Jeffrey S. Carter
;
John R. Springer
;
Darin E. Jones
;
Michael J. Hayes
;
Alexander F. Shaffer
;
Gina M. Jerome
;
Michael T. Baratta
;
Ben Zweifel
;
William M. Moore
;
Jaime L. Masferrer
;
Michael L. Vazquez
关键词:
Inflammation
;
m-PGES-1
;
Benzoxazole
;
Clinical candidate
;
PF-4693627
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design
作者:
Daniel P. Walker
;
dpwalker@kalexsyn.com
;
quassinoid@earthlink.net
;
Graciela B. Arhancet
;
Hwang-Fun Lu
;
Steven
E.
Heasley
;
Sue Metz
;
Natasha M. Kablaoui
;
Francisco M. Franco
;
Cathleen E. Hanau
;
Jeffrey A. Scholten
;
John R. Springer
;
Yvette M. Fobian
;
Jeffrey S. Carter
;
Li Xing
;
Shengtian Yang
;
Alexander F. Shaffer
;
Gina M. Jerome
;
Michael T. Baratta
;
William M. Moore
;
Michael L. Vazquez
关键词:
mPGES-1
;
Benzoxazole
;
Solubility
;
Acyl glucuronide
;
Conformational analysis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
3.
Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility
作者:
James A. Nieman
;
Sajiv K. Nair
;
Steven
E.
Heasley
;
Brenda L. Schultz
;
Herbert M. Zerth
;
Richard A. Nugent
;
Ke Chen
;
Kevin J. Stephanski
;
Todd A. Hopkins
;
Mary L. Knechtel
;
Nancee L. Oien
;
Janet L. Wie
关键词:
Pyrroloquinoline
;
Cytomegalovirus
;
HCMV
;
Varicella-zoster
;
Herpesvirus
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
4.
Solvent and in situ catalyst preparation impacts upon Noyori reductions of aryl-chloromethyl ketones: application to syntheses of chiral 2-amino-1-aryl-ethanols
作者:
Steven
P. Tanis
;
Bruce R. Evans
;
James A. Nieman
;
Timothy T. Parker
;
Wendy D. Taylor
;
Steven
E.
Heasley
;
Paul M. Herrinton
;
William R. Perrault
;
Richard A. Hohler
;
Lester A. Dolak
et al.
刊名:Tetrahedron: Asymmetry
出版年:2006
1
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