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内部出版物
在“
Elsevier电子期刊
”中,
命中:
29
条,耗时:小于0.01 秒
1.
Differences in protein binding and excretion of
Triapine
and its Fe(III) complex
作者:
Karla Pelivan
a
;
Walter Miklos
b
;
Sushilla van Schoonhoven
b
;
Gunda Koellensperger
d
;
Lars Gille
e
;
Walter Berger
b
;
c
;
Petra Heffeter
b
;
c
;
petra.heffeter@meduniwien.ac.at" class="auth_mail" title="E-mail the corresponding author
;
Christian R. Kowol
a
;
c
;
christian.kowol@univie.ac.at" class="auth_mail" title="E-mail the corresponding author
;
Bernhard K. Keppler
a
;
c
关键词:
Drug development
;
Thiosemicarbazones
;
Triapine
;
Pharmacokinetics
;
In vivo
刊名:Journal of Inorganic Biochemistry
出版年:2016
2.
Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase
作者:
Charles R. Myers
a
;
b
;
cmyers@mcw.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ANF
;
auranofin
;
cDDP
;
cisplatin (cis-diamminedichloroplatinum(II))
;
Cys
;
cysteine
;
DMSO
;
dimethylsulfoxide
;
DMEM
;
Dulbecco&rsquo
;
s Modified Eagle&rsquo
;
s Medium
;
Dp44mT
;
2
;
2&prime
;
-Dipyridyl-N
;
N-dimethylsemicarbazone
;
FBS
;
fetal bovine serum
;
Fe
;
iron
;
GPx
;
glutathione peroxidase
;
HBSS
;
Hank&rsquo
;
s balanced salt solution
;
L-NAME
;
L-NG-Nitroarginine methyl ester hydrochloride
;
NEM
;
N-ethylmaleimide
;
PMSF
;
phenylmethylsulfonyl fluoride
;
Prxs
;
peroxiredoxins
;
Prx1
;
peroxiredoxin-1 (cytosolic)
;
Prx
刊名:Free Radical Biology and Medicine
出版年:2016
3.
Vanadium(IV/V) complexes of
Triapine
and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity
作者:
Christian R. Kowol
a
;
b
;
christian.kowol@univie.ac.at" class="auth_mail" title="E-mail the corresponding author
;
Nó
;
ra V. Nagy
c
;
Tamá
;
s Jakusch
d
;
Alexander Roller
a
;
Petra Heffeter
b
;
e
;
Bernhard K. Keppler
a
;
b
;
É
;
va A. Enyedy
d
;
enyedy@chem.u-szeged.hu" class="auth_mail" title="E-mail the corresponding author
关键词:
Equilibria
;
Cytotoxicity
;
Stability constants
;
X-ray crystal structure
;
EPR spectroscopy
刊名:Journal of Inorganic Biochemistry
出版年:2015
4.
Triapine
Enhances Radiosensitivity of HPV Negative Head and Neck Squamous Cell Carcinoma Cells
作者:
K. Yao
;
R. Patel
;
G. Ferris
;
N.L. Oleinick
刊名:International Journal of Radiation Oncology*Biology*Physics
出版年:2015
5.
The anticancer thiosemicarbazones Dp44mT and
triapine
lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase II¦Á
作者:
Jack C. Yalowich
a
;
b
;
1
;
Xing Wu
c
;
Rui Zhang
c
;
Ragu Kanagasabai
a
;
Marisa Hornbaker
b
;
Brian B. Hasinoff
c
;
1
;
B_Hasinoff@UManitoba.ca
关键词:
Dp44mT
;
Triapine
;
Topoisomerase II¦Á
;
Cell cycle analysis
;
Iron
;
Thiosemicarbazone
刊名:Biochemical Pharmacology
出版年:2012
6.
Ribonucleotide reductase inhibition by metal complexes of
Triapine
(3-aminopyridine-2-carboxaldehyde thiosemicarbazone): A combined experimental and theoretical study
作者:
Ana
;
Popovi?-Bijeli?
a
;
;
1
;
Christian R.
;
Kowol
b
;
Maria E.S.
;
Lind
c
;
Jinghui
;
Luo
a
;
;
2
;
Fahmi
;
Himo
c
;
É
;
va A.
;
Enyedy
d
;
Vladimir B.
;
Arion
b
;
;
vladimir.arion@univie.ac.at
;
Astrid
;
Grä
;
slund
a
;
;
astrid@dbb.su.se
关键词:
Ribonucleotide reductase (RNR)
;
Triapine
;
Tyrosyl radical
;
Metal complex
;
Cytotoxicity
;
EPR
刊名:Journal of Inorganic Biochemistry
出版年:2011
7.
The iron-chelating drug
triapine
causes pronounced mitochondrial thiol redox stress
作者:
Judith M. Myers
a
;
William E. Antholine
b
;
c
;
Jacek Zielonka
b
;
c
;
Charles R. Myers
a
;
c
;
cmyers@mcw.edu
关键词:
Triapine
;
Thioredoxin-2
;
Peroxiredoxin-3
;
Thiol oxidation
刊名:Toxicology Letters
出版年:2011
8.
Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition
作者:
Darius J.R. Lane
;
Thomas M. Mills
;
Nurul H. Shafie
;
Angelica M. Merlot
;
Rayan Saleh Moussa
;
Danuta S. Kalinowski
;
Zaklina Kovacevic
;
Des R. Richardson
;
d.richardson@med.usyd.edu.au" class="auth_mail
关键词:
ASK1
;
apoptosis signal-regulating kinase 1
;
ATF4
;
activating transcription factor 4
;
ATF6
;
activating transcription factor 6
;
Bcl-2
;
B-cell lymphoma 2
;
BiP
;
binding immunoglobulin protein
;
bZIP
;
basic leucine zipper
;
CDK
;
cyclin-dependent kinase
;
CDKI
;
CDK inhibitors
;
CHOP
;
C/EBP homologous protein
;
DFO
;
desferrioxamine
;
dNTP
;
deoxyribonucleotide triphosphate
;
Dp44mT
;
di-2-pyridylketone 4
;
4-dimethyl-3- thiosemicarbazone
;
eIF2伪
;
eukaryotic initiation factor 2伪
;
EMT
;
epithelial&ndash
;
mesenchymal
刊名:Biochimica et Biophysica Acta (BBA)/Reviews on Cancer
出版年:April, 2014
9.
A Dose Escalation and Pharmacodynamic Study of
Triapine
and Radiation in Patients With Locally Advanced Pancreas Cancer
作者:
Ludmila Katherine Martin
;
John Grecula
;
Guang Jia
;
Lai Wei
;
Xiangyu Yang
;
Gregory A. Otterson
;
Xin Wu
;
Erica Harper
;
Cheryl Kefauver
;
Bing-Sen Zhou
;
Yun Yen
;
Mark Bloomston
;
Michael Knopp
;
S. Percy Ivy
;
Michael Grever
;
Tanios Bekaii-Saab
刊名:International Journal of Radiation Oncology*Biology*Physics
出版年:2012
10.
Radiochemotherapy plus 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in advanced-stage cervical and vaginal cancers
作者:
Charles A. Kunos
a
;
kunosc@summahealth.org
;
Tomas Radivoyevitch
b
;
Steven Waggoner
c
;
Robert Debernardo
c
;
Kristine Zanotti
c
;
Kimberly Resnick
c
;
Nancy Fusco
c
;
Ramon Adams
c
;
Raymond Redline
d
;
Peter Faulhaber
e
;
Afshin Dowlati
f
关键词:
Triapine
;
Cervical cancer
;
Ribonucleotide reductase
;
Radiosensitization
刊名:Gynecologic Oncology
出版年:2013
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