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在“Elsevier电子期刊”中，命中：116条，耗时：小于0.01 秒

在所有数据库中总计命中：41条

1.Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities

作者：Padma Nair ; Takashi Yamamoto ; Tally M. Largent-Milnes ; Scott Cowell ; Vinod Kulkarni ; Sharif Moye ; Edita Navratilova ; Peg Davis ; Shou-Wu Ma ; Todd W. V ; erah ; Josephine Lai ; Frank Porreca ; Victor J. Hruby

关键词：Bifunctional compounds ; Opioid receptor agonists ; Neutokinin-1 receptor antagonists ; Truncation of peptide sequence ; NMR structure

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

2.Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors

作者：Ramesh Alleti ; Josef Vagner ; Dilani Chathurika Dehigaspitiya ; Valerie E. Moberg ; N.G.R.D. Elshan ; Narges K. Tafreshi ; Nabila Brabez ; Craig S. Weber ; Ronald M. Lynch ; Victor J. Hruby ; Robert J. Gillies ; David L. Morse ; Eugene A. Mash

关键词：BSA ; bovine serum albumin ; Cl-HOBt ; 6-chloro-1-hydroxybenzotriazole ; CuAAC ; copper(I)-catalyzed azide-alkyne cycloaddition ; DCM ; dichloromethane ; DIC ; diisopropyl carbodiimide ; DIEA ; diisopropylethylamine ; DMEM ; Dulbecco&rsquo ; s Modified Eagle Medium ; DMF

刊名：Bioorganic and Medicinal Chemistry

出版年：2013

3.Novel fentanyl-based dual 渭/未-opioid agonists for the treatment of acute and chronic pain

作者：Alex ; er T. Podolsky ; Alex ; er S ; weiss ; Jackie Hu ; Edward J. Bilsky ; Jim P. Cain ; Vlad K. Kumirov ; Yeon Sun Lee ; Victor J. Hruby ; Ruben S. Vardanyan ; Todd W. V ; erah

关键词：Chronic pain ; Allodynia ; Hyperalgesia ; Inflammatory ; Mice ; Rat ; Fentanyl ; mu opioid ; Delta opioid ; Spinal nerve ligation ; Formalin flinch ; Naloxone

刊名：Life Sciences

出版年：18 December, 2013

4.Design of novel melanocortin receptor ligands: Multiple receptors, complex pharmacology, the challenge

作者：Victor J. Hruby ; ^a ; ^{hruby@u.arizona.edu"" rel=""nofollow} ; Minying Cai^a ; James Cain^a ; Joel Nyberg^a ; Dev Trivedi^a

关键词：Melanocortin receptor ligand SAR ; Selective ligand for MCR ; Melanocortin receptor selective ligand ; Orthosteric and allosteric ligand ; Agonists and antagonists for MCR

刊名：European Journal of Pharmacology

出版年：2011

5.Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors

作者：Alexander V. Mayorov^† ; ; ^a ; Minying Cai^a ; Erin S. Palmer^a ; Dustin K. Tanaka^a ; James P. Cain^a ; Matthew M. Dedek^a ; Bahar Tan^a ; Dev Trivedi^a ; Victor J. Hruby ; ^a ; ^{hruby@email.arizona.edu"" rel=""nofollow} ; ^{hruby@u.arizona.edu"" rel=""nofollow}

关键词：α ; -MSH ; Agouti-related protein ; Human melanocortin receptors ; Hybrid pharmacophore ; Macrocyclic peptide

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

6.Improved synthesis of d,l-fluorocitric acid

作者：Ruben Vardanyan ; ; ; ^{vardanyr@email.arizona.edu} ; Vlad K. Kumirov ; Victor J. Hruby

关键词：luorocitric acid

刊名：Journal of Fluorine Chemistry

出版年：2011

7.Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors

作者：Liping Xu ; Josef Vagner ; Ramesh Alleti ; Venkataramanarao Rao ; Bhumasamudram Jagadish ; David L. Morse ; Victor J. Hruby ; Robert J. Gillies ; Eugene A. Mash

关键词：Multimeric ligands ; Human melanocortin 4 receptor ; NDP-α ; -MSH ; MSH(4)

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2010

8.Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2

作者：Cesare Giordano ; Anna Sansone ; Annalisa Masi ; Gino Lucente ; Pasqualina Punzi ; Adriano Mollica ; Francesco Pinnen ; Federica Feliciani ; Ivana Cacciatore ; Peg Davis ; Josephine Lai ; Shou-Wu Ma ; Frank Porreca ; Victor Hruby

关键词：Endomorphins ; Opioid peptides ; Peptide synthesis ; β ; -Sulphonamido peptides ; Unusual amino acids

刊名：European Journal of Medicinal Chemistry

出版年：2010

9.Use of plasmon waveguide resonance (PWR) spectroscopy for examining binding, signaling and lipid domain partitioning of membrane proteins

作者：Victor J. Hruby ; Isabel Alves ; Scott Cowell ; Zdzislaw Salamon ; Gordon Tollin

关键词：PWR spectroscopy ; G-Protein coupled receptors ; Ligand binding ; Signaling ; Lipid domains

刊名：Life Sciences

出版年：2010

10.Optimization of time-resolved fluorescence assay for detection of europium–tetraazacyclododecyltetraacetic acid-labeled ligand–receptor interactions

作者：Channa R. De Silva ; Josef Vagner ; Ronald Lynch ; Robert J. Gillies ; Victor J. Hruby

关键词：DELFIA ; Lanthanide ; DOTA derivatives ; Time-resolved luminescence ; Binding assay ; Solid-phase peptide synthesis ; Melanocortin receptor

刊名：Analytical Biochemistry

出版年：2010

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