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在“Elsevier电子期刊”中，命中：23条，耗时：0.0129936 秒

在所有数据库中总计命中：211条

1.SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists

作者：Shuwen He ; ^{shuwen_he@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Peter H. Dobbelaar ; Liangqin Guo ; Zhixiong Ye ; Jian Liu ; Tianying Jian ; Quang Truong ; Shrenik K. Shah ; Wu Du ; Hongbo Qi ; Raman K. Bakshi ; Qingmei Hong ; James D. Dellureficio ; Edward Sherer ; Alexander Pasternak ; Zhe Feng ; Mikhail Reibarkh ; Melissa Lin ; Koppara Samuel ; Vijay B. Reddy ; Stan Mitelman ; Sharon X. Tong ; Gary G. Chicchi ; Kwei-Lan Tsao ; Dorina Trusca ; Margaret Wu ; Qing Shao ; Maria E. Trujillo ; Guillermo Fernandez ; Donald Nelson ; Patricia Bunting ; Janet Kerr ; Patrick Fitzgerald ; Pierre Morissette ; Sylvia Volksdorf ; George J. Eiermann ; Cai Li ; Bei B. Zhang ; Andrew D. Howard ; Yun-Ping Zhou ; Ravi P. Nargund ; William K. Hagmann

关键词：Somatostatin receptor subtype 3 ; Antagonist ; Tetrahydro-β-carboline ; hERG ; SAR

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.Discovery and development of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists for the treatment of diabetes

作者：Jonathan E. Wilson ; ^{jonathan_wilson@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Ravi Kurukulasuriya ; Christopher Sinz ; Matthew Lombardo ; Kate Bender ; Dann Parker ; Edward C. Sherer ; Melissa Costa ; Karen Dingley ; Xiaofang Li ; Stanley Mitelman ; Sharon Tong ; Randal Bugianesi ; Anka Ehrhardt ; Birgit Priest ; Kevin Ratliff ; Feroze Ujjainwalla ; Ravi Nargund ; William K. Hagmann ; Scott Edmondson

关键词：GPR142 ; g-protein coupled receptor 142 ; HTS ; high throughput screen ; PPB ; plasma protein binding ; CYP ; cytochrome P450

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy

作者：Laura Pisarsky¹ ; ² ; Ruben Bill¹ ; ² ; Ernesta Fagiani¹ ; Sarah Dimeloe¹ ; Ryan William Goosen¹ ; Jö ; rg Hagmann¹ ; Christoph Hess¹ ; Gerhard Christofori¹ ; ^{gerhard.christofori@unibas.ch" class="auth_mail" title="E-mail the corresponding author}

刊名：Cell Reports

出版年：2016

4.Synthesis and cannabinoid-1 receptor binding affinity of conformationally constrained analogs of taranabant

作者：Ihor E. Kopka ; Linus S. Lin ; James P. Jewell ; Thomas J. Lanza ; Tung M. Fong ; Chun-Pyn Shen ; Zhege J. Lao ; Sookhee Ha ; Laurie G. Castonguay ; Lex Van der Ploeg ; Mark T. Goulet ; William K. Hagmann

关键词：Cannabinoid ; CB1R ; Obesity ; Conformationally constrained

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2010

5.Synthesis of β-carbolines from aldehydes and ketones via the α-siloxy α,β-unsaturated esters

作者：Shuwen He ; Zhong Lai ; David X. Yang ; Qingmei Hong ; Mikhail Reibarkh ; Ravi P. Nargund ; William K. Hagmann

关键词：β ; -Carboline ; Pictet– ; Spengler reaction ; α ; -Siloxy α ; β ; -unsaturated ester ; Tryptamine ; α ; -Ketoester

刊名：Tetrahedron Letters

出版年：2010

6.Characterization of α₄β₁ (CD49d/CD29) on equine leukocytes: Potential utility of a potent α₄β₁ (CD49d/CD29) receptor antagonist in t

作者：Kelly M. Treonze ; Kenneth Alves ; Paul Fischer ; William K. Hagmann ; Donald Hora ; Alison Kulick ; Ken Vakerich ; Nicholas D. Smith ; Russell B. Lingham ; Salony Maniar ; Thomas S. Reger ; Jasmine Zunic ; Benit

关键词：α ; ₄β ; ₁ ; CD49d/CD29 ; VLA-4 ; Recurrent airway obstruction ; Heaves ; Horse

刊名：Veterinary Immunology and Immunopathology

出版年：2009

作者：Jing Chen Xiao ; James P. Jewell ; Linus S. Lin ; William K. Hagmann ; Tung M. Fong ; Chun-Pyn Shen

关键词：Human cannabinoid CB₁ receptor ; Human cannabinoid CB_1a receptor ; Human cannabinoid CB_1b receptor ; Endocannabinoid ; CB₁ receptor inverse agonist

刊名：Brain Research

出版年：2008

8.Constraining the amide bond in N-Sulfonylated dipeptide VLA-4 antagonists

作者：Linda L. Chang ; Ginger X. Yang ; Ermengilda McCauley ; Richard A. Mumford ; John A. Schmidt ; William K. Hagmann

关键词：VLA-4 ; Peptide bond mimetic ; Bicyclic VLA-4 antagonists ; Imidazole VLA-4 antagonists

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2008

9.A direct functionalization of tertiary alkyl bromides with O-, N-, and C-nucleophiles

作者：Petr Vachal ; Joan M. Fletcher ; William K. Hagmann

关键词：Tertiary bromide ; Silver oxide ; Nucleophile ; Steric hindrance ; Quaternary

刊名：Tetrahedron Letters

出版年：2007

10.A one-pot synthesis of 3-substituted-5-carbonylmethyl-1,2,4-oxadiazoles from β-keto esters and amidoximes under solvent-free conditions

作者：Wu Du ; Quang Truong ; Hongbo Qi ; Yan Guo ; Harry R. Chobanian ; William K. Hagmann ; Jeffrey J. Hale

刊名：Tetrahedron Letters

出版年：2007

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