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在“Elsevier电子期刊”中，命中：271条，耗时：0.0399472 秒

在所有数据库中总计命中：3,036条

1.Polar aromatic periphery increases agonist potency of spirocyclic free fatty acid receptor (GPR40) agonists inspired by LY2881835

作者：Mikhail Krasavin^a ; ^{m.krasavin@spbu.ru} ; Alexey Lukin^b ; Daria Bagnyukova^b ; Nikolay Zhurilo^b ; Aleksei Golovanov^b ; Sergey Zozulya^c ; ^d ; Ihor Zahanich^c ; Daniel Moore^e ; Irina G. Tikhonova^e

关键词：Drug discovery ; FFA1 agonists ; Antidiabetic agents ; Spirocyclic motifs ; Hydrophobic interactions ; π&minus ; π stacking

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.SERS characterization of neuropeptide Y and its C-terminal fragments deposited onto colloidal gold nanoparticle surface

作者：Helena Domin^a ; Natalia Piergies^b ; Dominika Święch^c ; Ewa Pięta^b ; Edyta Proniewicz^c ; ^{proniewi@agh.edu.pl}

关键词：Surface-enhanced Raman spectroscopy (SERS) ; Colloidal gold nanoparticles ; SERS spectra ; Neuropeptide Y ; Y2 receptor agonist ; C-terminal NPY fragments

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2017

3.Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835

作者：Mikhail Krasavin^a ; ^{m.krasavin@spbu.ru" class="auth_mail" title="E-mail the corresponding author} ; Alexey Lukin^b ; Daria Bagnyukova^b ; Nikolay Zhurilo^b ; Ihor Zahanich^c ; Sergey Zozulya^c ; ^d ; Jouni Ihalainen^e ; Markus M. Forsberg^e ; Marko Lehtonen^e ; Jarkko Rautio^e ; Daniel Moore^f ; Irina G. Tikhonova^f

关键词：GPCR ; GPR40 ; Free fatty acid receptor 1 ; FFA1 agonists ; Type 2 diabetes mellitus ; Prins reaction ; Spirocyclic motifs ; Metabolic stability

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Characterization of the surface geometry of acetyl-[Leu^28,31]-NPY(24-36), a selective Y₂ receptor agonist, onto the Ag and Au surfaces

作者：Helena Domin^a ; Dominika Święch^b ; Natalia Piergies^c ; Ewa Pięta^d ; Younkyoo Kim^e ; Edyta Proniewicz^b ; ^{proniewi@agh.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：Surface-enhanced Raman spectroscopy ; SERS ; Ag and Au surfaces ; Mutated C-terminal analogue of NPY ; Y2 receptor agonist

刊名：Vibrational Spectroscopy

出版年：2016

5.WAY208466 inhibits glutamate release at hippocampal nerve terminals

作者：Hue Yu Wang^a ; ^b ; Cheng Wei Lu^c ; ^d ; Tzu Yu Lin^c ; ^d ; Jinn Rung Kuo^e ; ^f ; Su Jane Wang^g ; ^{med0003@mail.fju.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：5-HT6 receptor ; WAY208466 ; Antidepressant ; Glutamate ; Synaptosomes ; Hippocampus

刊名：European Journal of Pharmacology

出版年：2016

6.Synergistic antidepressant-like effects between a kappa opioid antagonist (LY2444296) and a delta opioid agonist (ADL5859) in the mouse forced swim test

作者：Peng Huang ; Julia Tunis ; Christopher Parry ; Ronald Tallarida ; Lee-Yuan. Liu-Chen ; ^{lliuche@temple.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Kappa opioid antagonist ; Delta opioid agonist ; Antidepressant ; Synergy ; Forced swim test

刊名：European Journal of Pharmacology

出版年：2016

7.Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca²⁺ sensitization

作者：Chung-Pin Liu^a ; Jwu-Lai Yeh^b ; Shu-Fen Liou^c ; Bin-Nan Wu^b ; Ing-Jun Chen^b ; ^d ; ^{ingjun@kmu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：Ca2+ entry ; Cardiac output ; Cardioprotection ; PKG ; G-protein-coupled receptor

刊名：The Kaohsiung Journal of Medical Sciences

出版年：2016

8.Diquafosol promotes corneal epithelial healing via intracellular calcium-mediated ERK activation

作者：Yong-Soo Byun^a ; ^b ; Young-Sik Yoo^b ; Ji-Young Kwon^b ; Jong-Soo Joo^a ; Sung-A Lim^a ; Woong-Joo Whang^a ; Jee-Won Mok^b ; Jun-Sub Choi^b ; Choun-Ki Joo^a ; ^b ; ^{ckjoo@catholic.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Corneal epithelium ; Wound healing ; Diquafosol ; P2Y2 receptor agonist ; Purinergic P2Y2 receptor ; Uridine triphosphate ; Rat

刊名：Experimental Eye Research

出版年：2016

9.Cross-talk between 5-hydroxytryptamine and substance P in the melanogensis and apoptosis of B16F10 melanoma cells

作者：Jia Zhou^a ; ¹ ; Kun-kun Geng^b ; ¹ ; Feng-feng Ping^c ; Yue-ying Gao^a ; Lei Liu^a ; Bai-nian Feng^a ; ^{jnyxy2014@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：5-HT ; SP ; Cross-talk ; 5-HT2A receptor ; NK1 receptor ; Melanogenesis

刊名：European Journal of Pharmacology

出版年：2016

10.A pepducin designed to modulate P2Y₂R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism

作者：Michael Gabl^a ; ¹ ; André ; Holdfeldt^a ; ¹ ; Malene Winther^a ; Tudor Oprea^a ; ^b ; Johan Bylund^a ; ² ; Claes Dahlgren^a ; ^{Claes.Dahlgren@microbio.gu.se" class="auth_mail" title="E-mail the corresponding author} ; Huamei Forsman^a

关键词：P2Y2R ; Pepducins ; FPRs ; Neutrophils ; Inflammation

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

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