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内部出版物
在“
Elsevier电子期刊
”中,
命中:
35
条,耗时:小于0.01 秒
1.
An endocrine disruptor, bisphenol A, affects development in the protochordate Ciona intestinalis: Hatching rates and swimming behavior alter in a dose-dependent manner
作者:
Ayami Matsushima
a
;
b
;
ayami@chem.kyushu-univ.jp
;
Kerrianne Ryan
c
;
Yasuyuki
Shimohigashi
a
;
b
;
Ian A. Meinertzhagen
c
;
d
关键词:
Behavior
;
Bisphenol A
;
Ciona intestinalis
;
Embryo
;
Hatching rate
刊名:Environmental Pollution
出版年:2013
2.
Nanomolar dose of bisphenol A rapidly modulates spinogenesis in adult hippocampal neurons
作者:
Nobuaki Tanabe
a
;
1
;
Hinako Yoshino
a
;
1
;
Tetsuya Kimoto
a
;
c
;
Yasushi Hojo
a
;
c
;
d
;
Mari Ogiue-Ikeda
a
;
b
;
Yasuyuki
Shimohigashi
e
;
Suguru Kawato
a
;
b
;
c
;
d
;
kawato@phys.c.u-tokyo.ac.jp
;
kawato@bio.c.u-tokyo.ac.jp
关键词:
ACSF
;
artificial cerebrospinal fluid
;
AMPA
;
¦Á-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
;
BPA
;
bisphenol A
;
CNQX
;
6-cyano-7-nitroqui-noxaline-2
;
3-dione
;
DG
;
dentate gyrus
;
E2
;
17¦Â-estradiol
;
ER
;
estrogen receptor
;
ERR¦Ã
;
estrogen-related recepto
刊名:Molecular and Cellular Endocrinology
出版年:2012
3.
Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor ROR¦Ã
作者:
Mitsuhiro Nishigori
;
Takeru Nose
;
Yasuyuki
Shimohigashi
关键词:
BP
;
bisphenol
;
ER
;
estrogen receptor
;
ERR
;
estrogen-related receptor
;
25-HC
;
25-hydroxycholesterol
;
LBD
;
ligand-binding domain
;
LBP
;
ligand-binding pocket
;
PPAR
;
peroxisome proliferator-activated receptor
;
ROR¦Ã
;
retinoid-related orphan receptors ¦Ã
刊名:Toxicology Letters
出版年:2012
4.
Capturing of the free cysteine residue in the ligand-binding site by affinity labeling of the ORL1 nociceptin receptor
作者:
Ayami
;
Matsushima
;
Hirokazu
;
Nishimura
;
Shogo
;
Inamine
;
Shiho
;
Uemura
;
Yasuyuki
;
Shimohigashi
;
;
;
shimo@chem.kyushu-univ.jp
关键词:
Affinity labeling
;
N
-Ethylmaleimide
;
Nociceptin
;
ORL1 receptor
;
SNpys group
刊名:Bioorganic and Medicinal Chemistry
出版年:2011
5.
Spare interactions of highly potent [Arg
14
,Lys
15
]nociceptin for cooperative induction of ORL1 receptor activation
作者:
Kaname Isozaki
;
Jinglan Li
;
Kazushi Okada
;
Hirokazu Nishimura
;
Ayami Matsushima
;
Takeru Nose
;
Tommaso Costa
;
Yasuyuki
Shimohigashi
关键词:
Binding site
;
Nociceptin
;
Receptor activation
;
Site-directed mutagenesis
;
Synergistic effect
刊名:Bioorganic and Medicinal Chemistry
出版年:2009
6.
Discriminatory synergistic effect of Trp-substitutions in superagonist [(Arg/Lys)
14
, (Arg/Lys)
15
]nociceptin on ORL1 receptor binding and activation
作者:
Hirokazu Nishimura
;
Jinglan Li
;
Kaname Isozaki
;
Kazushi Okada
;
Ayami Matsushima
;
Takeru Nose
;
Tommaso Costa
;
Yasuyuki
Shimohigashi
关键词:
Basic amino acids
;
Antagonist
;
Nociceptin
;
Synergistic potentiation
;
Superagonist
刊名:Bioorganic and Medicinal Chemistry
出版年:2009
7.
Exploration of endocrine-disrupting chemicals on estrogen receptor α by the agonist/antagonist differential-docking screening (AADS) method: 4-(1-Adamantyl)phenol as a potent endocrine disruptor candidate
作者:
Takeru Nose
;
Takatoshi Tokunaga
;
Yasuyuki
Shimohigashi
关键词:
Endocrine disruptor
;
Estrogen receptor α
;
Docking calculation
刊名:Toxicology Letters
出版年:2009
8.
ERRγ tethers strongly bisphenol A and 4-α-cumylphenol in an induced-fit manner
作者:
Ayami Matsushima
;
Takamasa Teramoto
;
Hiroyuki Okada
;
Xiaohui Liu
;
Takatoshi Tokunaga
;
Yoshimitsu Kakuta
;
Yasuyuki
Shimohigashi
关键词:
Bisphenol A
;
4-α
;
-Cumylphenol
;
Endocrine disruptor
;
Estrogen-related receptor γ
;
(ERRγ
) ;
Nuclear receptor
;
X-ray crystal structure
刊名:Biochemical and Biophysical Research Communications
出版年:2008
9.
Relationship between the results of in vitro receptor binding assay to human estrogen receptor α and in vivo uterotrophic assay: Comparative study with 65 selected chemicals
作者:
Yumi Akahori
;
Makoto Nakai
;
Kanji Yamasaki
;
Mineo Takatsuki
;
Yasuyuki
Shimohigashi
;
Masahiro Ohtaki
关键词:
Binding assay
;
Uterotrophic assay
;
Concordance
刊名:Toxicology in Vitro
出版年:2008
10.
Designed modification of partial agonist of ORL1 nociceptin receptor for conversion into highly potent antagonist
作者:
Jinglan Li
;
Kaname Isozaki
;
Kazushi Okada
;
Ayami Matsushima
;
Takeru Nose
;
Tommaso Costa
;
Yasuyuki
Shimohigashi
关键词:
Acyl group
;
Antagonist
;
Nociceptin
;
Structure–
;
activity relationships
刊名:Bioorganic and Medicinal Chemistry
出版年:2008
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