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在“Elsevier电子期刊”中，命中：152条，耗时：0.0699671 秒

在所有数据库中总计命中：546条

1.Significance of integrated in silico transmural ventricular wedge preparation models of human non-failing and failing hearts for safety evaluation of drug candidates

作者：Taeko Kubo ; DVM ; PhD^a ; ^b ; ^c ; ^{taeko-kubo@ds-pharma.co.jp} ; ^{taekok2016@gmail.com} ; Takashi Ashihara ; MD ; PhD^b ; Tadashi Tsubouchi ; PhD^a ; Minoru Horie ; MD ; PhD^b

关键词：AP ; action potential ; APD ; action potential duration ; APD30 ; APD at 30% repolarization ; APD90 ; APD at 90% repolarization ; APD30&ndash ; 90 ; APD90&ndash ; APD30 ; [Ca2 ; +]i ; intracellular Ca2 ; + concentration ; CiPA ; Comprehensive in vitro Proarrhythmia Assay ; CV ; conduction velocity ; EAD ; early afterdepolarization ; ECG ; electrocardiogram ; Endo ; endocardial ; Epi ; epicardial ; FH ; failing heart ; ICH ; International Conference of Harmonization ; IQ-CSRC ; Innovation and Quality in Pharmaceutical Deve

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

2.Experimental evidence for a severe proarrhythmic potential of levosimendan

作者：Gerrit Frommeyer^a ; ^{gerrit.frommeyer@ukmuenster.de} ; Anja Kohnke^a ; Christian Ellermann^a ; Dirk G. Dechering^a ; Simon Kochhä ; user^a ; Christian Pott^a ; Michael Fehr^b ; Lars Eckardt^a

关键词：Levosimendan ; Therapeutic safety ; Ventricular refractory period ; Ventricular fibrillation

刊名：International Journal of Cardiology

出版年：2017

3.The positive frequency-dependent electrophysiological effects of the I_Kur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation

作者：John Ford ; PhD^* ; James Milnes ; PhD^* ; Said El Haou ; PhD^* ; Erich Wettwer ; PhD^&dagger ; ; Simone Loose ; MD^&dagger ; ; Klaus Matschke ; MD^&Dagger ; ; Benoit Tyl ; MD^§ ; ; Patrick Round ; MBBS^* ; Ursula Ravens ; MD^&dagger ; ; ^{ravens@rcs.urz.tu-dresden.de" class="auth_mail" title="E-mail the corresponding author}

关键词：AF ; atrial fibrillation ; ANOVA ; analysis of variance ; AP ; action potential ; APA ; action potential amplitude ; APD20 ; APD50 ; APD90 ; action potential duration at 20% ; 50% ; and 90% of repolarization ; cAF ; chronic atrial fibrillation ; DMSO ; dimethyl sulfoxide ; dV/dtmax ; maximum upstroke velocity ; ECG ; electrocardiogram/electrocardiographic ; ERP ; effective refractory period ; HR ; heart rate ; IKur ; ultra-rapidly activating delayed-rectifier potassium current ; pAF ; paroxysmal atrial fibrillation ; PLT20

刊名：Heart Rhythm

出版年：2016

4.Sarcolemmal Ca²⁺-entry through L-type Ca²⁺ channels controls the profile of Ca²⁺-activated Cl⁻ current in canine ventricular myocytes

作者：Balá ; zs Horvá ; th^a ; ^b ; ¹ ; Krisztina Vá ; czi^a ; ¹ ; Bence Hegyi^a ; Mó ; nika Gö ; nczi^a ; ^c ; Beatrix Dienes^a ; Korné ; l Kistamá ; s^a ; Tamá ; s Bá ; nyá ; sz^a ; Já ; nos Magyar^a ; ^d ; Istvá ; n Baczkó ; ^e ; Andrá ; s Varró ; ^e ; ^f ; Gyö ; rgy Sepré ; nyi^g ; Lá ; szló ; Csernoch^a ; Pé ; ter P. Ná ; ná ; si^a ; ^h ; Norbert Szentandrá ; ssy^a ; ^h ; ^{szentandrassy.norbert@med.unideb.hu" class="auth_mail" title="E-mail the corresponding author}

关键词：9-AC ; 9-anthracene carboxylic acid ; AP ; action potential ; APVC ; action potential voltage-clamp ; APD90 ; action potential duration at 90% of repolarization ; BKCa ; large-conductance Ca2+-activated K+ channels ; CaT ; calcium transient ; Cav1.2 ; pore forming subunit of L-type Ca2+ channel ; [Ca2+]cleft ; Ca2+ concentration in the dyadic cleft ; [Ca2+]i ; intracellular Ca2+ concentration in bulk cytoplasm ; [Cl&minus ; ]i ; intracellular Cl&minus ; concentration ; CDI ; Ca2+-dependent inactivation ; CICR ; Ca2+-indu

刊名：Journal of Molecular and Cellular Cardiology

出版年：2016

5.Human ex-vivo action potential model for pro-arrhythmia risk assessment

作者：Guy Page^a ; Phachareeya Ratchada^a ; Yannick Miron^a ; Guido Steiner^b ; Andre Ghetti^a ; Paul E. Miller^a ; Jack A. Reynolds^a ; Ken Wang^b ; Andrea Greiter-Wilke^b ; Liudmila Polonchuk^b ; Martin Traebert^c ; Gary A. Gintant^d ; Najah Abi-Gerges^a ; ^{Najah.abigerges@anabios.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Human heart ; Ventricular trabeculae ; Action potential ; Pro-arrhythmia assessment ; Drug discovery and development

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

6.Effects of Ang Ⅱ perfusion on transmural heterogeneous of Cx43 in acute myocardial ischemia reperfusion

作者：Xiao-Pan Chen¹ ; Shi-Juan Lu² ; Kang Huang² ; Wei Zhang² ; Zheng-Wang Liu¹ ; Jiang-Hua Zhong² ; ^{zhong3882@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Acute myocardial ischemia reperfusion ; Dispersion of repolarization ; Cx43 ; Angiotensin Ⅱ

刊名：Asian Pacific Journal of Tropical Medicine

出版年：2016

7.Beat-to-beat electrocardiographic analysis of ventricular repolarization variability in patients after myocardial infarction

作者：Pedro D. Arini ; PhD^a ; ^b ; ^{pedro.arini@conicet.gov.ar" class="auth_mail" title="E-mail the corresponding author} ; Esteban R. Valverde ; MEng^a ;

关键词：T-wave spectral variance ; Heterogeneity of ventricular repolarization ; Myocardial infarction ; Electrical remodeling

刊名：Journal of Electrocardiology

出版年：2016

8.Reduced response to I_Kr blockade and altered hERG1a/1b stoichiometry in human heart failure

作者：Katherine M. Holzem^a ; Juan F. Gomez^b ; Alexey V. Glukhov^a ; Eli J. Madden^a ; Aaron C. Koppel^a ; Gregory A. Ewald^a ; Beatriz Trenor^b ; Igor R. Efimov^a ; ^c ; ^{igor@wustl.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AP ; action potential ; APD ; action potential duration ; APD80 ; action potential duration at 80% repolarization ; D ; donor ; Endo ; endocardium ; Epi ; epicardium ; HF ; heart failure ; F ; failing ; LV ; left ventricle ; Mid ; midmyocardium

刊名：Journal of Molecular and Cellular Cardiology

出版年：2016

9.Divergent electrophysiologic profile of fluconazole and voriconazole in an experimental whole-heart model of proarrhythmia

作者：Gerrit Frommeyer^a ; ^{gerrit.frommeyer@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Christina Fischer^a ; Philipp S. Lange^a ; Patrick Leitz^a ; Michael Fehr^b ; Harilaos Bogossian^c ; Peter Milberg^a ; Lars Eckardt^a

关键词：Fluconazole ; Voriconazole ; Dispersion of repolarization ; Proarrhythmia ; Sudden cardiac death

刊名：European Journal of Pharmacology

出版年：2016

10.Potent Inhibition of hERG Channels by the Over-the-Counter Antidiarrheal Agent Loperamide

关键词：action potential ; hERG ; loperamide ; QT ; torsade de pointes

刊名：JACC: Clinical Electrophysiology

出版年：2016

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