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在“Elsevier电子期刊”中，命中：81条，耗时：0.0619709 秒

在所有数据库中总计命中：702条

1.Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice

作者：Neelam Shahani ; Wen-Chin Huang ; Megan Varnum ; Damon T. Page ; Srinivasa Subramaniam ; ^{ssubrama@scripps.edu}

关键词：Rheb ; Forebrain ; BACE1 ; Spatial memory ; Alzheimer's disease

刊名：Neurobiology of Aging

出版年：2017

2.Strand-specific RNA-sequencing analysis of multiple system atrophy brain transcriptome

作者：J.D. Mills^a ; M. Ward^a ; W.S. Kim^b ; ^c ; G.M. Halliday^b ; ^c ; M. Janitz^a ; ^{m.janitz@unsw.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：BACE1 ; beta-site APP-cleaving enzyme 1 ; BACE1-AS ; beta-site APP-cleaving enzyme 1 antisense ; BLAT ; BLAST-like alignment tool ; CAMK2A ; calcium/calmodulin-dependent protein kinase II alpha ; CNP ; 23 ; -cyclic nucleotide 3 ; phosphodiesterase ; COQ2 ; Q2 4-hydroxybenzoate polyprenyltransferase ; CTGF ; connective tissue growth factor ; DAVID ; Database for Annotation ; Visualization and Integrated Discovery ; DEGs ; differentially expressed genes ; DTNBP1 ; dystrobrevin binding protein 1 ; EIF4EBP1 ; eukaryotic tr

刊名：Neuroscience

出版年：2016

3.Targeting sphingosine-1-phosphate signaling in lung diseases

作者：David L. Ebenezer^a ; Panfeng Fu^b ; Viswanathan Natarajan^a ; ^b ; ^c ; ^d ; ^{visnatar@uic.edu}

关键词：4-DP ; 4&prime ; -deoxypridoxine ; ABC transporter ; ATP-binding cassette transporter ; Akt ; protein kinase B ; ALF4 ; tetrafluoroaluminate ; ALI ; acute lung injury ; ARDS ; acute respiratory distress syndrome ; ASM ; acid sphingomyelinase ; BACE1 ; beta-site APP-cleaving enzyme ; BAL ; bronchoalveolar lavage ; BMDC ; bone marrow derived cells ; BPD ; broncho pulmonary dysplasia ; CDK-2 ; cyclin dependent kinase ; CF ; Cystic fibrosis ; CFTR ; Cystic fibrosis transmembrane conductance regulator ; CoA ; co enzyme A ; COPD ; ch

刊名：Pharmacology & Therapeutics

出版年：2016

4.TSPO ligand PK11195 alleviates neuroinflammation and beta-amyloid generation induced by systemic LPS administration

作者：Li Ma^a ; ^b ; ¹ ; Hui Zhang^c ; ¹ ; Na Liu^d ; Pei-qi Wang^a ; Wen-zhi Guo^b ; Qiang Fu^a ; Lin-bo Jiao^b ; Ya-qun Ma^b ; Wei-Dong Mi^a ; ^{mi_wd301@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Aβ ; β-amyloid protein ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BACE ; β-site APP cleaving enzyme ; BDNF ; brain-derived neurophic factor ; COX ; cyclooxygenase ; IDE ; insulin-degrading enzyme ; LPS ; lipopolysaccharide ; MWM ; Morris water maze ; SEM ; standard error of the mean ; TSPO ; translocator protein 18 ; kDa

刊名：Brain Research Bulletin

出版年：2016

5.Proteolytic processing of Neuregulin-1

作者：Michael Willem ^{Michael.Willem@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author} ^{mwillem@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author}

关键词：AD ; Alzheimer&rsquo ; s disease ; ADAM ; a disintegrin and metalloprotease ; Aβ ; Amyloid β-peptide ; APP ; β-amyloid precursor protein ; BACE1 ; beta-site APP cleaving enzyme 1 ; CTF ; C-terminal fragment ; EGF ; epidermal growth factor ; ICD ; intracellular domain ; I-CLiP ; intramembrane cleaving protease ; MMP ; matrix-metallo-protease ; NRG1 ; Neuregulin-1 ; PS ; presenilin ; RIP ; regulated intramembrane proteolysis ; SPP ; signal peptide peptidase ; SNP ; single nucleotide polymorphism ; TACE ; tumor necrosis factor-α c

刊名：Brain Research Bulletin

出版年：2016

6.Hydrogen sulfide ameliorates learning memory impairment in APP/PS1 transgenic mice: A novel mechanism mediated by the activation of Nrf2

作者：Yuangui Liu ; Yuanyuan Deng ; Huiyu Liu ; Caixia Yin ; Xiaohui Li ; Qihai Gong ; ^{gqh@zmc.edu.cn}

关键词：AD ; Alzheimer's disease ; Aβ ; beta-amyloid ; APP ; beta-amyloid precursor protein ; ARE ; antioxidant response element ; BACE1 ; β-site APP-cleaving enzyme 1 ; CBS ; cystathionine-β-synthase ; DG ; dentate gyrus ; GST ; glutathione S-transferase ; HO-1 ; heme oxygenase-1 ; Keap1 ; Kelch-like ECH-associated protein 1 ; 3MST ; 3-mercaptopyruvate sulfurtransferase ; NaHS ; sodium hydrosulfide ; NS ; normal saline ; Nrf2 ; nuclear factor-erythroid 2-related factor2

刊名：Pharmacology Biochemistry and Behavior

出版年：2016

7.Meta-analysis of BACE1 gene rs638405 polymorphism and the risk of Alzheimer’s disease in Caucasion and Asian population

作者：Minhua Yu ; Yue Liu ; Jun Shen ; Dongwei Lv ; Junjian Zhang ; ^{wdsjkx@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：APP ; amyloid precursor protein ; BACE ; β-site APP cleaving enzyme ; AD ; Alzheimer&rsquo ; s disease ; SNP ; single-nucleotide polymorphism ; Aβ ; amyloid beta-peptide ; HWE ; Hardy-Weinberg equilibrium ; ApoE ; Apolipoprotein E

刊名：Neuroscience Letters

出版年：2016

8.Sox2 functionally interacts with βAPP, the βAPP intracellular domain and ADAM10 at a transcriptional level in human cells

作者：G. Sarlak^a ; ^b ; H.H. Htoo^b ; J.-F. Hernandez^c ; H. Iizasa^d ; F. Checler^e ; U. Konietzko^f ; W. Song^g ; B. Vincent^a ; ^b ; ^h ; ^{bruno.vin@mahidol.ac.th" class="auth_mail" title="E-mail the corresponding author}

关键词：AD ; Alzheimer&rsquo ; s disease ; Aβ ; amyloid-β peptide ; ADAM ; a disintegrin and metalloprotease ; AICD ; APP intracellular domain ; BACE1 ; beta-site APP cleaving enzyme 1 ; EDTA ; ethylenediaminetetraacetic acid ; FBS ; fetal bovine serum ; HEK ; human embryonic kidney ; HRP ; horseradish peroxidase ; IPSCs ; induced-pluripotent stem cells ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; NPCs ; neural progenitor cells ; NSCs ; neural stem cells ; PBS ; phosphate-buffered saline ; SDS ; sodium dodecyl sulfate ; S

刊名：Neuroscience

出版年：2016

9.Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitors

作者：Yong-Jin Wu^a ; ^{Yong-Jin.Wu@bms.com" class="auth_mail" title="E-mail the corresponding author} ; Jason Guernon^a ; Ramkumar Rajamani^a ; Jeremy H. Toyn^a ; ^&dagger ; ; Michael K. Ahlijanian^a ; Charles F. Albright^a ; Jodi Muckelbauer^b ; ChiehYing Chang^b ; Dan Camac^b ; John E. Macor^b ; Lorin A. Thompson^a

关键词：BACE1 inhibitor ; Furo[2 ; 3-d][1 ; 3]thiazinamine ; Alzheimer&rsquo ; s disease

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.MicroRNA-328a regulates water maze performance in PTZ-kindled rats

作者：Yuhan Liao^a ; Yiqing Huang^a ; Xixia Liu^a ; Chun Luo^a ; Donghua Zou^a ; Xing Wei^a ; Qi Huang^a ; Yuan Wu^a ; ^b ; ^{wuyuan90@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：miR-328a ; microRNA-328a ; PTZ ; pentylenetetrazole ; TLE ; temporal lobe epilepsy ; MWM ; Morris water maze ; BACE ; beta-site APP-cleaving enzyme ; APP ; amyloid precursor protein ; Abeta ; amyloid beta ; AD ; Alzheimer's disease

刊名：Brain Research Bulletin

出版年：2016

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