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内部出版物
在“
Elsevier电子期刊
”中,
命中:
209
条,耗时:小于0.01 秒
1.
Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders
作者:
Kui-Ming Hung
a
;
b
;
Pei-Chun Chen
b
;
Han-Chieh Hsieh
c
;
Marcus J Calkins
a
;
mjcalkins@mail.ncku.edu.tw
关键词:
NRTI
;
nucleoside/nucleotide reverse transcriptase inhibitor
;
HAND
;
HIV-associated neurocognitive disorders
;
cART
;
combination antiretroviral therapy
;
pol γ
;
polymerase γ
;
mtDNA
;
mitochondrial DNA
;
ddI
;
didanosine
;
AZT
;
zidovudine
;
FTC
;
emtricitabine
;
TDF
;
tenofovir
;
ddC
;
zalcitabine
;
d4T
;
stavudine
;
3TC
;
lamivudine
;
ABC
;
abacavir
;
PGC-1α
;
peroxisome proliferator-activated receptor γ coactivator 1α
;
mtUPR
;
mitochondrial unfolded protein response
;
CO1
;
Cytochrome oxidase I
;
ND1
;
NADH Dehydrogenase
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
2.
Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them
作者:
Alejandro Sosnik
a
;
b
;
sosnik@tx.technion.ac.il" class="auth_mail" title="E-mail the corresponding author
;
alesosnik@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Robin Augustine
a
关键词:
ABC
;
ATP-binding cassette superfamily pump
;
AIDS
;
Acquired Immunodeficiency syndrome
;
API
;
Active pharmaceutical ingredient
;
ARVs
;
Antiretrovirals
;
AUC
;
Area-under-the-curve
;
AZT
;
Zidovudine
;
BCS
;
Biopharmaceutic Classification System
;
BCRP
;
Breast cancer resistance protein
;
b.i.d.
;
Twice-a-day
;
BMS
;
Burning mouth syndrome
;
CD
;
Cyclodextrin
;
CEHDA
;
Concentric electrohydrodynamic atomization
;
CMC
;
Critical micellar concentration
;
CNS
;
Central nervous system
;
ddI
;
Didanosine
;
DDS
;
Drug delivery sy
刊名:Advanced Drug Delivery Reviews
出版年:2016
3.
E17A mutation in HIV-1 Vpr confers resistance to
didanosine
in association with thymidine analog mutations
作者:
Slim Fourati
a
;
b
;
c
;
slim.fourati@psl.aphp.fr
;
Isabelle Malet
a
;
b
;
c
;
Carolin A. Guenzel
d
;
e
;
f
;
Cathia Soulie
a
;
b
;
c
;
Priscilla Maidou-Peindara
d
;
e
;
f
;
Laurence Morand-Joubert
a
;
c
;
g
;
Marc Wirden
a
;
b
;
c
;
Sophie Sayon
a
;
b
;
c
;
Gilles Peytavin
h
;
Anne Simon
b
;
Christine Katlama
a
;
b
;
c
;
Serge Benichou
d
;
e
;
f
;
Vincent Calvez
a
;
b
;
c
;
Anne-Geneviè
;
ve Marcelin
a
;
b
;
c
关键词:
HIV-1
;
Vpr
;
Drug resistance
;
Didanosine
刊名:Antiviral Research
出版年:2012
4.
Analysis of in vivo absorption of
didanosine
tablets in male adult dogs by HPLC
作者:
Patrí
;
cia Severino
a
;
b
;
Heloisa Silva
c
;
Eliana B. Souto
d
;
e
;
eliana@ufp.edu.pt
;
souto.eliana@gmail.com
;
Maria Helena A. Santana
a
;
Teresa Cristina T. Dalla Costa
b
关键词:
Didanosine
;
On-line solid phase extraction
;
HPLC
;
Male dogs
刊名:Journal of Pharmaceutical Analysis
出版年:2012
5.
Preparation of gastro-resistant pellets containing chitosan microspheres for improvement of oral
didanosine
bioavailability
作者:
Patrí
;
cia Severino
a
;
George G.G. de Oliveira
b
;
Humberto G. Ferraz
b
;
Eliana B. Souto
c
;
d
;
eliana@ufp.edu.pt
;
Maria H.A. Santana
a
;
lena@feq.unicamp.br
;
souto.eliana@gmail.com
关键词:
Didanosine
;
Pellets
;
Gastro-resistance
;
Coating
;
Microspheres
;
Chitosan
刊名:Journal of Pharmaceutical Analysis
出版年:2012
6.
Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies
作者:
Hervé
;
Hillaireau
a
;
b
;
1
;
Nathalie Dereuddre-Bosquet
c
;
d
;
1
;
Rym Skanji
a
;
b
;
Fawzia Bekkara-Aounallah
a
;
b
;
e
;
Joachim Caron
a
;
b
;
Sinda Lepê
;
tre
a
;
b
;
Sé
;
bastien Argote
f
;
Laurent Bauduin
g
;
Rahima Yousfi
c
;
Christine Rogez-Kreuz
c
;
Didier Desmaë
;
le
a
;
b
;
Bernard Rousseau
f
;
Ruxandra Gref
a
;
b
;
Karine Andrieux
a
;
b
;
Pascal Clayette
c
;
Patrick Couvreur
a
;
b
;
patrick.couvreur@u-psud.fr
关键词:
Squalenoylation
;
Nanoassemblies
;
Prodrug
;
Didanosine
;
Zalcitabine
刊名:Biomaterials
出版年:2013
7.
Monolayered multipolymeric buccal films with drug and polymers of opposing solubilities for ARV therapy: Physico-mechanical evaluation and molecular mechanics modelling
作者:
Elsab¨¦ Jones
;
Elizabeth Ojewole
;
Viness Pillay
;
Pradeep Kumar
;
Sanjeev Rambharose
;
Thirumala Govender
关键词:
Didanosine
;
Buccal
;
Films
;
Co-blended polymers
;
Physico-mechanical properties
;
Static lattice atomistic simulations
刊名:International Journal of Pharmaceutics
出版年:2013
8.
Simultaneous determination of
didanosine
and its amino acid prodrug, val
didanosine
by hydrophilic interaction chromatography coupled with electrospray ionization tandem mass spectrometry: Application to a pharmacokinetic study in rats
作者:
Zhongtian Yan
;
Jin Sun
;
Jinling Wang
;
Youjun Xu
;
Yannan Chang
;
Ping Meng
;
Meng Zhu
;
Qiang Fu
;
Yongbing Sun
;
Zhonggui He
关键词:
Ultra-performance liquid chromatography–
;
tandem mass spectrometry
;
Didanosine
;
Val
didanosine
;
Solid-phase extraction
;
Hydrophilic interaction
;
Pharmacokinetic study
刊名:Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年:2010
9.
Antiretroviral therapy and drug resistance in human immunodeficiency virus type 2 infection
作者:
Luis Men茅ndez-Arias
;
Mar 脕lvarez
关键词:
HIV-2
;
Reverse transcriptase
;
Drug resistance
;
Protease
;
Integrase
;
Entry inhibitors
刊名:Antiviral Research
出版年:February, 2014
10.
The role of nucleoside reverse transcriptase inhibitors usage in the incidence of hyperlactatemia and lactic acidosis in HIV/AIDS patients
作者:
Gordana Dragovic
a
;
gozza@beotel.net
;
Djordje Jevtovic
b
关键词:
Nucleoside analogs
;
Didanosine
;
Stavudine
;
Hyperlactatemia
;
Lactic acidosis
刊名:Biomedicine and Pharmacotherapy
出版年:2012
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