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CNKI会议论文(1)
CNKI学位论文(3644)
CNKI期刊论文0611(9)
知网期刊论文(1216)
在“
Elsevier电子期刊
”中,
命中:
309
条,耗时:0.0229895 秒
在所有数据库中总计命中:
4,870
条
1.
(E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its
dual
inhibitory effects on XOD and URAT1
作者:
Qinghua Hu
a
;
b
;
1
;
Mengze Zhou
b
;
c
;
1
;
Haoran Zhu
b
;
Guo Lu
b
;
Dongsen Zheng
b
;
Huanqiu Li
d
;
huanqiuli@suda.edu.cn
;
Kun Hao
a
;
chinacpu1001@163.com
关键词:
(E)-2-(4-bromophenyl)-1-(2
;
4-dihydroxyphenyl)ethanone oxime
;
Hyperuricemia
;
Xanthine
oxidase
;
Urate transporter 1
;
Dual
inhibitor
刊名:Biomedicine & Pharmacotherapy
出版年:2017
2.
Multitarget drug design strategy against Alzheimer’s disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine
oxidase
B
dual
inhibitors with multifunctional properties
作者:
Yan Li
a
;
Xiaoming Qiang
a
;
Li Luo
a
;
Xia Yang
a
;
Ganyuan Xiao
a
;
Yunxiaozhu Zheng
a
;
Zhongcheng Cao
a
;
Zhipei Sang
b
;
Fu Su
a
;
sufu@scu.edu.cn
;
Yong Deng
a
;
dengyong@scu.edu.cn
关键词:
Alzheimer&rsquo
;
s disease
;
Homoisoflavonoid
;
Mannich base derivatives
;
Acetylcholinesterase inhibitors
;
Monoamine
oxidase
B inhibitors
;
Multifunctional properties
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
3.
DL-3-n-butylphthalide-Edaravone hybrids as novel
dual
inhibitors of amyloid-β aggregation and monoamine
oxidase
s with high antioxidant potency for Alzheimer’s therapy
作者:
Xiaoming Qiang
a
;
Yan Li
a
;
Xia Yang
a
;
Li Luo
a
;
Rui Xu
a
;
Yunxiaozhu Zheng
a
;
Zhongcheng Cao
a
;
Zhenghuai Tan
b
;
tanzhh616@163.com
;
Yong Deng
a
;
dengyong@scu.edu.cn
关键词:
Alzheimer&rsquo
;
s disease
;
DL-NBP-Edaravone hybrids
;
Aβ aggregation inhibitors
;
MAO inhibitors
;
Antioxidant
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
4.
Discovery of novel curcumin derivatives targeting xanthine
oxidase
and urate transporter 1 as anti-hyperuricemic agents
作者:
Gui-Zhen Ao
a
;
Meng-Ze Zhou
b
;
Yu-Yao Li
a
;
Si-Ning Li
a
;
Hua-Nian Wang
a
;
Qian-Wen Wan
a
;
Huan-Qiu Li
a
;
huanqiuli@suda.edu.cn
;
Qing-Hua Hu
b
;
huqh@cpu.edu.cn
关键词:
Xanthine
oxidase
;
Urate transporter 1
;
Anti-hyperuricemic
;
Uricosuric
;
Curcumin derivatives
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
5.
Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine
oxidase
B and
dual
MAO-A/B inhibitors
作者:
Nikolay T. Tzvetkov
a
;
ntzvetkov@ntzlab.com
;
Hans-Georg Stammler
b
;
Beate Neumann
b
;
Silvia Hristova
c
;
Liudmil Antonov
c
;
Marcus Gastreich
d
关键词:
ADME
;
MAO inhibitors
;
Molecular modeling
;
Indazole-5-carboxamides
;
Parkinson's disease
;
X-ray
刊名:European Journal of Medicinal Chemistry
出版年:2017
6.
Subcellular localization of the FLT3-ITD oncogene plays a significant role in the production of NOX- and p22
phox
-derived reactive oxygen species in acute myeloid leukemia
作者:
Jennifer N. Moloney
;
Joanna Stanicka
;
Thomas G. Cotter
;
t.cotter@ucc.ie
关键词:
FLT3
;
FMS-like tyrosine kinase 3 receptor
;
FLT3-ITD
;
FLT3-internal tandem duplication
;
FLT3-WT
;
FLT3- wild type
;
NOX
;
NADPH
oxidase
;
p22phox
;
p22 phagocyte
oxidase
;
ROS
;
reactive oxygen species
;
AML
;
acute myeloid leukemia
;
ER
;
endoplasmic reticulum
;
H2O2
;
hydrogen peroxide
;
PO1
;
peroxy orange 1
;
RTK
;
receptor tyrosine kinase
;
COX
;
cyclooxygenase
;
DUOX
;
dual
oxidase
;
DMSO
;
dimethylsulfoxide
刊名:Leukemia Research
出版年:2017
7.
Chemoprotective role of molybdo-flavoenzymes against xenobiotic compounds
作者:
Khaled S. Al Salhen
;
Khaled.alsalhen@omu.edu.ly
关键词:
Aldehyde
oxidase
;
Xanthine oxidoreductase
;
Chemoprotection and Drosophila melanogaster
刊名:Journal of the Association of Arab Universities for Basic and Applied Sciences
出版年:2017
8.
Lysyl
Oxidase
3 Is a
Dual
-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation
作者:
Li Ma
1
;
3
;
10
;
Chao Huang
1
;
2
;
10
;
c_huang_bio@msn.com
;
Xiong-Jun Wang
1
;
10
;
Dazhuan Eric Xin
1
;
10
;
Li-shun Wang
1
;
Quanli C. Zou
1
;
Ya-nan S. Zhang
1
;
Min-dian Tan
1
;
Yu-mei Wang
1
;
Ting C. Zhao
3
;
Devasis Chatterjee
3
;
Rachel A. Altura
3
;
Chuangui Wang
4
;
Yan S. Xu
5
;
Jing-hua Yang
5
;
Yong-sheng Fan
6
;
Bao-hui Han
2
;
Jianmin Si
7
;
Xiaoren Zhang
1
;
Jinke Cheng
8
;
Zhijie Chang
9
;
zhijiec@tsinghua.edu.cn
;
Y. Eugene Chin
1
;
11
;
yechin@sibs.ac.cn
刊名:Molecular Cell
出版年:2017
9.
The innate immune response to RSV: Advances in our understanding of critical viral and host factors
作者:
Yan Sun
;
Carolina B. Ló
;
pez
;
lopezca@upenn.edu
关键词:
ATF6
;
activated transcription factor 6
;
BAP31
;
B-cell receptor-associated protein 31
;
Bcl2
;
B-cell lymphoma 2
;
DR4/5
;
death receptor 4/5
;
DUOX2
;
dual
oxidase
2
;
DVGs
;
defective viral genomes
;
IB
;
inclusion body
;
IFIT1
;
interferon-induced protein with tetratricopeptide repeats 1
;
iNOS
;
inducible nitric oxide synthase
;
IRE1
;
inositol-requiring enzyme 1
;
JAK-STAT
;
Janus kinase/signal transducers and activators of transcription
;
MDA5
;
melanoma differentiation-associated protein 5
;
MyD88
;
myeloid dif
刊名:Vaccine
出版年:2017
10.
Dual
oxidase
s participate in the regulation of intestinal microbiotic homeostasis in the kuruma shrimp Marsupenaeus japonicus
作者:
Hui-Ting Yang
;
Ming-Chong Yang
;
Jie-Jie Sun
;
Xiu-Zhen Shi
;
Xiao-Fan Zhao
;
Jin-Xing Wang
;
jxwang@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Intestinal innate immune
;
Reactive oxygen species
;
Dual
oxidase
;
Bacteria population
;
Marsupenaeus japonicus
刊名:Developmental & Comparative Immunology
出版年:2016
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