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在“Elsevier电子期刊”中，命中：7,386条，耗时：0.0489724 秒

在所有数据库中总计命中：24,475条

1.Activation of the Extracellular Signal-Regulated Kinase in the Amygdale Modulates Fentanyl-Induced Hypersensitivity in Rats

作者：Zhen Li^&lowast ; ; ^&dagger ; ; Pingping Yin^&lowast ; ; ^&dagger ; ; Jian Chen^&lowast ; ; Chenhong Li^&lowast ; ; Jieqiong Liu^&dagger ; ; Hemanshu Rambojan^&dagger ; ; Fang Luo^&dagger ; ; ^{luofang0909@hotmail.com}

关键词：Pain ; opioid-induced hyperalgesia ; extracellular signal-regulated MAP kinases ; central amygdaloid nucleus ; central nervous system sensitization ; long-term potentiation

刊名：The Journal of Pain

出版年：2017

2.Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer

作者：Atsushi Nakamura ; ^{atsushi_nakamura@shionogi.co.jp} ; Hiroko Ono ; Azusa Ando ; Mikie Hinata ; Kazuki Niidome ; Shigeki Omachi ; Gaku Sakaguchi ; Shunji Shinohara

关键词：Antinociception ; Bone cancer pain ; Extracellular regulated kinase ; Opioid ; Rewarding effect

刊名：Journal of Pharmacological Sciences

出版年：2017

3.Anesthetics inhibit extracellular signal-regulated Kinase1/2 phosphorylation via NMDA receptor, phospholipase C and protein kinase C in mouse hippocampal slices

作者：Gao Haiying^a ; Han Mingjie^a ; Zhang Lingyu^a ; Wang Qingxiang^a ; Wang Haisong^a ; Zhang Bingxi^b ; ^{zbxtryy@126.com}

关键词：Anesthetics ; Extracellular signal-regulated Kinase1/2 ; Phosphorylation ; Hippocampus ; Phospholipase C ; Protein kinase C

刊名：Neurochemistry International

出版年：2017

4.5-HT₇ receptor-mediated fear conditioning and possible involvement of extracellular signal-regulated kinase

作者：Kotaro Takeda ; Minoru Tsuji ; ^{mtsuji@iuhw.ac.jp} ; Kazuya Miyagawa ; Hiroshi Takeda

关键词：5-HT ; serotonin ; DR4004 ; 2a-[4-(4-phenyl-123 ; 6-tetrahydropyridyl)butyl]-2a34 ; -tetrahydrobenzo(c ; d)indol-2-(1H)-one ; ERK ; extracellular signal-regulated kinase 1/2 ; pERK ; phosphorylated ERK ; CS ; conditioned stimulus ; US ; unconditioned stimulus ; mRNA ; messenger RNA ; i.p. ; intraperitoneally ; ANOVA ; analysis of variance ; TrkB ; tropomyosin-related kinase B ; BDNF ; brain-derived neurotrophic factor

刊名：Neuroscience Letters

出版年：2017

5.Perilla frutescens leaves extract ameliorates ultraviolet radiation-induced extracellular matrix damage in human dermal fibroblasts and hairless mice skin

作者：Jung-Soo Bae^a ; ^b ; ^c ; ¹ ; Mira Han^a ; ^b ; ^c ; ¹ ; Hee Soon Shin^d ; Min-Kyoung Kim^a ; ^b ; ^c ; Chang-Yup Shin^a ; ^b ; ^c ; Dong Hun Lee^a ; ^b ; ^c ; ^{ivymed27@snu.ac.kr} ; Jin Ho Chung^a ; ^b ; ^c ; ^e ; ^{jhchung@snu.ac.kr}

关键词：AP-1 ; activator protein-1 ; ECM ; extracellular matrix ; EMSA ; electrophoretic mobility shift assays ; ERK ; extracellular signal-regulated kinase ; HDF ; human dermal fibroblast ; JNK ; c-Jun N-terminal kinase ; MED ; minimal erythema dose ; MMP ; matrix metalloproteinases ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)&minus2 ; 5-diphenyltetrazolium bromide ; PBS ; phosphate-buffered saline ; PLE ; Perilla frutescens leaves extract ; ROS ; reactive oxygen species ; SDS-PAGE ; sodium dodecyl sulfate-polyacrylamide gel electropho

刊名：Journal of Ethnopharmacology

出版年：2017

6.Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21^WAF1/CIP1 and p27^KIP1

作者：Jung-Jin Lee^a ; ^{mhjj3998@kiom.re.kr} ; Ji-Hye Lee^a ; ^{ideal0723@kiom.re.kr} ; Min Jung Gu^a ; ^{guminjung@kiom.re.kr} ; Joo-Hui Han^b ; ^{han5621@cnu.ac.kr} ; Won-Kyung Cho^a ; ^{wkcho@kiom.re.kr} ; Jin Yeul Ma^a ; ^{jyma@kiom.re.kr}

关键词：AKT ; phosphatidylinositol 3-kinase-linked protein kinase ; A.rugose ; Agastacherugosa Kuntze ; BrdU ; bromodeoxyuridine ; CA ; caffeic acid ; CCK-8 ; cell counting Kit-8 ; CDK ; cyclin-dependent kinase ; CKI ; cyclin-dependent kinase inhibitor ; DAD ; diode array UV/VIS detector ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; ERK ; extracellular signal regulated kinase 1/2 ; FBS ; fetal bovine serum ; HPLC ; high-performance liquid chromatographic ; JNK ; c-Jun N-terminal kinase ; PBS ; phosphate-buffered salin

刊名：Journal of Functional Foods

出版年：2017

7.Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation

作者：Wei Wu^a ; ^b ; Mahendra D. Chordia^c ; ^g ; Barry P. Hart^d ; E. Sathyajith Kumarasinghe^c ; Min K. Ji^c ; Ajay Bhargava^e ; Michael W. Lawlor^f ; Ji-Yeon Shin^a ; ^b ; Fusako Sera^a ; Shunichi Homma^a ; Antoine Muchir^a ; ^b ; ^h ; Uday R. Khire^c ; ^d ; ^{ukhire@allomek.com} ; Howard J. Worman^a ; ^b ; ^{hjw14@columbia.edu}

关键词：Cardiomyopathy ; Emery-Dreifuss muscular dystrophy ; Extracellular signal-regulated kinase ; Lamin ; MEK inhibitor ; Mitogen-activated protein kinase

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

8.Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway

作者：Xin Sun^a ; ¹ ; Qifei Deng^b ; ¹ ; Zhaofeng Liang^c ; Zhiqi Liu^a ; Hao Geng^a ; Li Zhao^a ; Qirui Zhou^d ; Jie Liu^a ; Jiaxing Ma^a ; Daming Wang^a ; Dexin Yu^a ; ^{yudx_urology@126.com} ; Caiyun Zhong^e ; ^{cyzhong@njmu.edu.cn}

关键词：CSE ; Cigarette smoke extract ; CS ; Cigarette smoke ; EMT ; Epithelial&ndash ; mesenchymal transition ; MAPK ; Mitogen-activated protein kinase ; ERK1/2 ; extracellular regulated protein kinases 1 and 2 ; AP-1 ; activator protein 1 ; DMSO ; dimethyl sulfoxide ; MTT ; thiazolyl blue tetrazolium bromide ; qRT-PCR ; quantitative reverse transcription-polymerase chain reaction

刊名：Biomedicine & Pharmacotherapy

出版年：2017

9.Analgesic effect of coumarins from Radix angelicae pubescentis is mediated by inflammatory factors and TRPV1 in a spared nerve injury model of neuropathic pain

作者：Ruili Li^a ; ¹ ; Chao Zhao^a ; ¹ ; Minna Yao^a ; Ying Song^b ; Yin Wu^a ; ; Aidong Wen^a ; ^{lwrcll@163.com}

关键词：CRAP ; Coumarins from Radix angelicae pubescentis ; SNI ; spared nerve injury ; DRG ; dorsal root ganglion ; CRAP ; coumarins from Radix angelicae pubescentis ; IL-1β ; interleukin-1β ; IL-6 ; interleukin-6 ; TNF-α ; tumor necrosis factor-α ; TRPV1 ; Transient receptor potential cation channel 1 ; pERK ; Phosphorylated extracellular regulated protein kinases ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinases ; LOD ; limit of detection ; LOQ ; limit of quantification ; ELISA ; Enzyme-linked immunosorbent

刊名：Journal of Ethnopharmacology

出版年：2017

10.Expression and activation of platelet-derived growth factor β receptor, mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) in canine mammary tumours

作者：Gennaro Altamura^a ; ^{gennaro.altamura@unina.it} ; Barbara degli Uberti^b ; ^{barbara.degliuberti@cert.izsmportici.it} ; Giorgio Galiero^b ; ^{giorgio.galiero@cert.izsmportici.it} ; Manuela Martano^a ; ^{manuela.martano@unina.it} ; Antonella Pirro^a ; ^{divas3@hotmal.it} ; Marco Russo^a ; ^{marco.russo@unina.it} ; Giuseppe Borzacchiello^a ; ^{borzacch@unina.it}

关键词：PDGFβR ; MEK ; ERK ; TKR inhibitors ; Oncology

刊名：Research in Veterinary Science

出版年：2017

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