搜索页_+fed-state+simulated+intestinal+fluids

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

常用资源

在“Elsevier电子期刊”中，命中：15条，耗时：0.0419852 秒

在所有数据库中总计命中：40条

1.Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin

作者：Rami Ojarinta^a ; ^{rami.ojarinta@uef.fi} ; Aki T. Heikkinen^b ; ^a ; Elina Sievä ; nen^c ; Riikka Laitinen^a

关键词：AA ; amino acid ; ACN ; acetonitrile ; ARG ; arginine ; AUC ; area under the curve ; CA ; co-amorphous ; DMSO ; dimethyl sulfoxide ; DS ; degree of supersaturation ; DSC ; differential scanning calorimetry ; EGF ; excipient gain factor ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; FTIR ; Fourier transform infrared spectroscopy ; HPLC ; high performance liquid chromatography ; IND ; indomethacin ; PHE ; phenylalanine ; PM ; physical mixture ; SF ; supersaturation factor ; ssN

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

2.Evaluation of mesoporous carbon aerogels as carriers of the non-steroidal anti-inflammatory drug ibuprofen

作者：Georgios K. Eleftheriadis^a ; Maria Filippousi^b ; Vassiliki Tsachouridou^c ; ^d ; Maria-Anna Darda^a ; Lamprini Sygellou^d ; Ioanna Kontopoulou^e ; Nikolaos Bouropoulos^e ; Theodore Steriotis^f ; Georgia Charalambopoulou^f ; Ioannis S. Vizirianakis^c ; Gustaaf Van Tendeloo^b ; Dimitrios G. Fatouros^a ; ^{dfatouro@pharm.auth.gr}

关键词：Carbon aerogels ; Poorly soluble drugs ; Simulated intestinal fluids ; Oral delivery

刊名：International Journal of Pharmaceutics

出版年：2016

3.Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

作者：Cecilie Maria Madsen^a ; Ben Boyd^b ; Thomas Rades^a ; ^{Thomas.Rades@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author} ; Anette Mü ; llertz^a ; ^c

关键词：Preformulation ; Food effects ; Precipitation inhibitors ; Amorphous ; Biorelevant media ; Bioavailability

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

作者：Johan P. Boetker^a ; Jukka Rantanen^a ; Læ ; rke Arnfast^a ; Maria Doreth^a ; Dhara Raijada^a ; ¹ ; Korbinian Loebmann^a ; Cecilie Madsen^a ; Jamal Khan^b ; Thomas Rades^a ; Anette Mü ; llertz^a ; Adrian Hawley^d ; Diana Thomas^e ; ² ; Ben J. Boyd^b ; ^c ; ^{ben.boyd@monash.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Carbamazepine ; Nitrofurantoin ; Solution-mediated transformation ; Synchrotron ; PCA ; Micelles

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

5.Physicochemical properties and in vitro intestinal permeability properties and intestinal cell toxicity of silica particles, performed in simulated gastrointestinal fluids

作者：Kumiko Sakai-Kato ; Masayuki Hidaka ; Keita Un ; Toru Kawanishi ; Haruhiro Okuda

关键词：DDS ; drug delivery system ; PDI ; polydispersity index ; TEM ; transmission electron microscopy ; FaSSGF ; fasted-state simulated gastric fluids ; FeSSGF ; fed-state simulated gastric fluids ; FaSSIF ; fasted-state simulated intestinal fluids ; FeSSIF ; fed-state simulated intestinal fluids ; DMEM ; Dulbecco's modified Eagle's medium ; PBS ; Phosphate buffer saline ; HBSS ; Hanks' balanced salt solution ; FBS ; fetal bovine serum ; TEER ; transepithelial electrical resistance

刊名：Biochimica et Biophysica Acta (BBA)/General Subjects

出版年：March, 2014

6.A review of drug solubility in human intestinal fluids: Implications for the prediction of oral absorption

作者：Patrick Augustijns^a ; ^{Patrick.Augustijns@pharm.kuleuven.be" class="auth_mail} ; Benjamin Wuyts^a ; Bart Hens^a ; Pieter Annaert^a ; James Butler^b ; Joachim Brouwers^a

关键词：Human intestinal fluid ; Simulated intestinal fluid ; Oral absorption ; Solubility ; Jejunal solubility ; Duodenal solubility

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

7.Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

作者：Christel A.S. Bergströ ; m^a ; ^{christel.bergstrom@farmaci.uu.se" class="auth_mail} ; René ; Holm^b ; Sø ; ren Astrup Jø ; rgensen^c ; Sara B.E. Andersson^a ; Per Artursson^a ; Stefania Beato^d ; Anders Borde^e ; Karl Box^f ; Marcus Brewster^g ; Jennifer Dressman^h ; Kung-I. Fengⁱ ; Gavin Halbert^j ; Edmund Kostewicz^h ; Mark McAllister^k ; Uwe Muenster^l ; Julian Thinnes^h ; Robert Taylor^f ; Anette Mullertz^c

关键词：ADMET ; absorption ; distribution metabolism ; elimination ; toxicity ; API ; active pharmaceutical ingredient ; BS ; bilesalt ; BS/PL ; bile salt to phospholipid ratio ; CMC ; critical micellar concentration ; DDI ; drug&ndash ; drug interaction ; FaSSGF ; fasted state simulated gastric fluid ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSGF ; fed state simulated gastric fluid ; FeSSIF ; fed state simulated intestinal fluid ; GI ; gastrointestinal ; HGF ; human gastric fluid ; HIF ; human intestinal fluid ; IVIVC

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

8.Intestinal drug solubility estimation based on simulated intestinal fluids: Comparison with solubility in human intestinal fluids

作者：Sarah Clarysse^a ; ¹ ; ^{sarah.clarysse@pharm.kuleuven.be"" rel=""nofollow} ; Joachim Brouwers^a ; ¹ ; ^{joachim.brouwers@pharm.kuleuven.be"" rel=""nofollow} ; Jan Tack^b ; ^{Jan.Tack@med.kuleuven.be"" rel=""nofollow} ; Pieter Annaert^a ; ^{pieter.annaert@pharm.kuleuven.be"" rel=""nofollow} ; Patrick Augustijns^a ; ^{patrick.augustijns@pharm.kuleuven.be"" rel=""nofollow}

关键词：TPGS ; Solubilizing capacity ; Solubility estimation ; Human intestinal fluids ; Simulated intestinal fluids ; Drug discovery

刊名：European Journal of Pharmaceutical Sciences

出版年：2011

9.Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine

作者：Nico Holmstock^a ; ^{nico.holmstock@pharm.kuleuven.be} ; Tom De Bruyn^a ; ^{tom.debruyn@pharm.kuleuven.be} ; Jan Bevernage^a ; ^{jan.bevernage@pharm.kuleuven.be} ; Pieter Annaert^a ; ^{pieter.annaert@pharm.kuleuven.be} ; Raf Mols^a ; ^{raf.mols@pharm.kuleuven.be} ; Jan Tack^b ; ^{jan.tack@med.kuleuven.be} ; Patrick Augustijns^a ; ^{patrick.augustijns@pharm.kuleuven.be}

关键词：Human intestinal fluids ; Mouse ; in situ intestinal perfusion ; Food effects ; Indinavir

刊名：European Journal of Pharmaceutical Sciences

出版年：2013

10.Bile salt composition is secondary to bile salt concentration in determining hydrocortisone and progesterone solubility in intestinal mimetic fluids

作者：Huda Zughaid ; Ben Forbes ; Gary P. Martin ; Nilesh Patel ; ^{N.Patel@kingston.ac.uk}

关键词：Solubility ; Simulated intestinal fluids ; Hydrocortisone ; Progesterone ; Lecithin ; Bile salts

刊名：International Journal of Pharmaceutics

出版年：2012

按检索点细分(15)

关键词(1)

文摘(13)

按出版年细分(15)

2027年及以后(1)

2017年(1)

2016年(3)

2013年(1)

2012年(3)

2011年(1)

2009年(1)

2008年(1)

2004年(1)

2000年及以前(2)