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在“Elsevier电子期刊”中，命中：2条，耗时：小于0.01 秒

1.A potent and selective inhibitor targeting human and murine 12/15-LOX

作者：Michelle M. Armstrong^a ; Cody J. Freedman^a ; Joo Eun Jung^b ; Yi Zheng^b ; Chakrapani Kalyanaraman^c ; Matthew P. Jacobson^c ; ^&dagger ; ; Anton Simeonov^d ; David J. Maloney^d ; Klaus van Leyen^b ; Ajit Jadhav^d ; Theodore R. Holman^a ; ^{holman@ucsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：LOX ; lipoxygenase ; hLOX ; human lipoxygenase ; h15-LOX-2 ; human epithelial 15-lipoxygenase-2 ; h12/15-LOX ; h15-LOX-1 ; human reticulocyte 15-lipoxygenase-1 ; h12-LOX ; human platelet 12-lipoxygenase ; s15-LOX-1 ; soybean 15-lipoxygenase-1 ; h5-LOX ; human leukocyte 5-lipoxygenase ; AA ; arachidonic acid ; LA ; linoleic acid ; 12-HETE ; 12-hydroxy-58 ; 10 ; 14-eicosatetraenoic acid ; 12-HpETE ; 12-hydroperoxyeicosatetraenoic acid ; 15-HpETE ; 15-hydroperoxyeicosatetraenoic acid ; 13-HpODE ; 13-(S)-hydroperoxyoctadecadien

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

2.Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency

作者：Michelle Armstrong^a ; Christopher van Hoorebeke^a ; Thomas Horn^a ; ^&dagger ; ; Joshua Deschamps^a ; J. Cody Freedman^a ; Chakrapani Kalyanaraman^b ; Matthew P. Jacobson^b ; Theodore Holman^a ; ^{holman@ucsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：LOX ; lipoxygenase ; h15-LOX-1 ; human reticulocyte 15-lipoxygenase-1 ; tPA ; tissue plasminogen activator ; FDA ; Food and Drug Administration ; s15-LOX-1 ; soybean 15-lipoxygenase-1 ; r15-LOX ; rabbit reticulocyte 15-LOX ; AA ; arachidonic acid ; 12-HpETE ; 12-hydroperoxyeicosatetraenoic acid ; LA ; linoleic acid ; 9R-HpODE ; 9-(R)-hydroperoxyoctadecadienoic acid ; 13-HpODE ; 13-(S)-hydroperoxyoctadecadienoic acid ; 15-HpETE ; 15-hydroperoxyeicosatetraenoic acid ; ICP-MS ; inductively coupled plasma mass spectrometer

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

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