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在“Elsevier电子期刊”中，命中：1,064条，耗时：0.0269867 秒

在所有数据库中总计命中：6,214条

1.Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function

作者：Zhengrong Yang^a ; Qingxian Zhou^a ; Leo Mok^b ; Anukriti Singh^b ; Douglas J. Swartz^b ; Ina L. Urbatsch^b ; ^{ina.urbatsch@ttuhsc.edu} ; Christie G. Brouillette^a ; ^c ; ^{christie@uab.edu}

关键词：AMPPCP ; β ; γ-methylene ATP ; CD ; circular dichroism ; CU ; cooperative unit ; CFTR ; cystic fibrosis transmembrane conductance regulator ; DDM ; n-dodecyl-β-d-maltopyranoside ; ΔHc ; calorimetric enthalpy ; DLS ; dynamic light scattering ; DMNG ; decyl maltose neopentyl glycol ; DSC ; differential scanning calorimetry ; ΔTm ; shift in thermal unfolding temperature ; His6&ndash ; Smt3 ; hexahistidine-SUMO protein tag ; ICL ; intracellular loop ; IMP ; integral membrane protein ; LS ; light scattering ; LUV ; large unilamella

刊名：Biochimica et Biophysica Acta (BBA) - Biomembranes

出版年：2017

2.Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study

作者：Terezinha M Souza ; ^{t.souza@maastrichtuniversity.nl} ; Linda Rieswijk ^{linda.rieswijk@maastrichtuniversity.nl} ; Twan van den Beucken ^{t.vandenbeucken@maastrichtuniversity.nl} ; Jos Kleinjans ^{j.kleinjans@maastrichtuniversity.nl} ; Danyel Jennen ^{danyel.jennen@maastrichtuniversity.nl}

关键词：Hepatocellular carcinoma ; Aflatoxin B1 ; Feed-forward loop ; Network motif ; Transcription factor

刊名：Toxicology

出版年：2017

3.A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22

作者：Tobias Engel ; ^{tengel@rcsi.ie} ; Gary P. Brennan ; Amaya Sanz-Rodriguez ; Mariana Alves ; Edward Beamer ; Orla Watters ; David C. Henshall ; Eva M. Jimenez-Mateos

关键词：CA1 and 3 ; Cornu amonis 1 and 3 ; ChIP ; chromatin immunoprecipitation ; DG ; Dentate gyrus ; IATF ; Injury-activated transcription factor family ; IL-1β ; Interleukin-1β ; miRNA ; microRNA ; NMDAR ; N-methyl-D-aspartate receptor ; p2rx7 ; P2X7 receptor gene name ; P2X7R ; purinergic P2X7 receptor ; Sp1 ; Specificity protein 1

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

出版年：2017

4.Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε

作者：Yu Yang^a ; ¹ ; Tingting Xu^a ; ¹ ; Yunfei Zhang^b ; Ximing Qin^a ; ^{qin.ximing@ahu.edu.cn}

关键词：ATP ; adenosine triphosphate ; CK1 ; casein kinase 1 ; CK2 ; casein kinase 2 ; CTD ; C-terminal domain ; TTFL ; transcriptional and translational feedback loop ; GSK-3β ; glycogen synthase kinase 3β ; MEFs ; mouse embryonic fibroblast cells ; ConA ; concanavalin A ; LPS ; lipopolysaccharide ; PKD2 ; protein kinase D2 ; mGluRs ; metabotropic glutamate receptors ; DHPG ; (S)-3 ; 5-dihydroxyphenylglycine ; DARPP-32 ; dopamine and cAMP-regulated phosphoprotein ; MAP1A ; microtubule associated protein 1A ; CLS ; centrosome localiz

刊名：Cellular Signalling

出版年：2017

5.Structure-guided development of covalent TAK1 inhibitors

作者：Li Tan^a ; ^b ; ^j ; Deepak Gurbani^c ; ^d ; ^j ; Ellen L. Weisberg^e ; ^f ; John C. Hunter^c ; ^d ; Lianbo Li^c ; ^d ; Douglas S. Jones^g ; ^h ; Scott B. Ficarro^a ; ^b ; Samar Mowafy^a ; ^b ; ⁱ ; Chun-Pong Tam^a ; ^b ; Suman Rao^a ; ^b ; ^g ; Guangyan Du^a ; ^b ; James D. Griffin^e ; ^f ; Peter K. Sorger^g ; Jarrod A. Marto^a ; ^b ; Kenneth D. Westover^c ; ^d ; ^{Kenneth.Westover@UTSouthwestern.edu} ; Nathanael S. Gray^a ; ^b ; ^{Nathanael_Gray@dfci.harvard.edu}

关键词：Structure-based design ; TAK1 kinase inhibitors ; Covalent inhibitors ; 2 ; 4-Disubstituted pyrimidine ; Structure-activity relationship

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

6.Zinc Binding Induces Conformational Changes in the Large Intracellular Loop of the Human Zinc Transporter hZIP4

刊名：Biophysical Journal

出版年：2017

7.Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy

作者：Maegan M. Weltzin^a ; ^{maeganweltzin@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jon M. Lindstrom^b ; ^{jslkk@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Ronald J. Lukas^a ; ^{Ronald.Lukas@dignityhealth.org" class="auth_mail" title="E-mail the corresponding author} ; Paul Whiteaker^a ; ^{Paul.Whiteaker@dignityhealth.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Nicotinic acetylcholine receptor ; Nocturnal frontal lobe epilepsy ; α4β2 isoform ; Cytoplasmic loop

刊名：Neuropharmacology

出版年：2016

8.Topogenesis and cell surface trafficking of GPR34 are facilitated by positive-inside rule that effects through a tri-basic motif in the first intracellular loop

作者：Haruki Hasegawa ; ^{harukih@amgen.com" class="auth_mail" title="E-mail the corresponding author} ; ^{h.haruki@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Neha Patel ; Elham Ettehadieh ; Peng Li ; Ai Ching Lim

关键词：DIC ; differential interference contrast ; ER ; endoplasmic reticulum ; GPCR ; G protein-coupled receptor ; HEK ; human embryonic kidney ; TCEP ; tris(2-carboxyethyl)phosphine

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

9.β₂-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop

作者：Matthew T. Eddy¹ ; ⁴ ; Tatiana Didenko² ; ⁴ ; Raymond C. Stevens¹ ; Kurt Wü ; thrich² ; ³ ; ⁵ ; ^{wuthrich@scripps.edu}

关键词：membrane proteins ; solution nuclear magnetic resonance ; G-protein-coupled receptors ; 19F NMR spectroscopy ; protein dynamics ; structural biology ; solution NMR ; β2-adrenergic receptor ; fusion protein ; integrative structural biology

刊名：Structure

出版年：2016

10.A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights

关键词：SDF-1 ; stromal cell-derived factor 1 ; GPCR ; G protein-coupled receptor ; CNS ; central nervous system ; NS ; nervous system ; DRG ; dorsal root ganglion ; OPC ; oligodendrocyte precursor cell ; MS ; multiple sclerosis ; PDB ; Protein Data Bank ; TM ; transmembrane ; EL ; extracellular loop ; IL ; intracellular loop ; NT ; N-terminus ; SD ; steepest descend ; CG ; conjugate gradient ; TN ; truncated Newton ; EM ; energy minimization ; GBSW ; Generalized Born with a simple switching ; ABNR ; adopted basis Newton&ndash ; Raphson ; R

刊名：Cellular Signalling

出版年：2016

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