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在“Elsevier电子期刊”中，命中：2,034条，耗时：小于0.01 秒

1.Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [¹¹C]ABP688 PET imaging and ex vivo immunoblotting

作者：Xiaotian T. Fang^a ; Jonas Eriksson^b ; ^c ; Gunnar Antoni^b ; ^c ; Ulrika Yngve^b ; ^c ; Linda Cato^a ; Lars Lannfelt^a ; Dag Sehlin^a ; Stina Syvä ; nen^a ; ^{stina.syvanen@pubcare.uu.se}

关键词：PET ; Alzheimer's disease ; mGluR5 ; [11C]ABP688

刊名：Neuropharmacology

出版年：2017

2.MPP⁺ inhibits mGluR1/5-mediated long-term depression in mouse hippocampus by calpain activation

作者：Junyao Li^a ; ¹ ; Hui Chen^a ; ¹ ; Shengbing Wu^a ; Yuefa Cheng^b ; Qinglin Li^a ; Jing Wang^a ; ^{wangjing2161@126.com} ; Guoqi Zhu^a ; ^{guoqizhu@gmail.com}

关键词：MPP+ ; Calpain ; DHPG ; Hippocampus ; Long-term depression

刊名：European Journal of Pharmacology

出版年：2017

3.Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[¹¹C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([¹¹C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain

作者：Yufei Ma^a ; ^b ; ¹ ; Katsushi Kumata^a ; ¹ ; Joji Yui^a ; Yiding Zhang^a ; Tomoteru Yamasaki^a ; Akiko Hatori^a ; Masayuki Fujinaga^a ; Nobuki Nengaki^a ; Lin Xie^a ; Hui Wang^b ; Ming-Rong Zhang^a ; ^{zhang.ming-rong@qst.go.jp}

关键词：[11C]CMDC ; In vitro autoradiography ; Metabotropic glutamate receptor 2 ; Positron emission tomography ; Radiotracer ; Schizophrenia

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Metabotropic glutamate receptors and neurodegenerative diseases

作者：Fabiola M. Ribeiro^a ; Luciene B. Vieira^b ; Rita G.W. Pires^c ; Roenick P. Olmo^a ; Stephen S.G. Ferguson^d ; ^{sferguso@uottawa.ca}

关键词：AMPA ; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid ; Aβ ; amyloid β peptide ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BDNF ; brain derived neurotrophic factor ; BF ; basal forebrain ; CGA ; chromogranin A ; CNS ; central nervous system ; DAG ; diacylghycerol ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; GDNF ; glial cell line-derived neurotrophic factor ; GIRK ; inward rectifying K+ channels ; GP ; globus pallidum ; GPe ; globus pallidum externa ; GPCR ; G

刊名：Pharmacological Research

出版年：2017

5.Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε

作者：Yu Yang^a ; ¹ ; Tingting Xu^a ; ¹ ; Yunfei Zhang^b ; Ximing Qin^a ; ^{qin.ximing@ahu.edu.cn}

关键词：ATP ; adenosine triphosphate ; CK1 ; casein kinase 1 ; CK2 ; casein kinase 2 ; CTD ; C-terminal domain ; TTFL ; transcriptional and translational feedback loop ; GSK-3β ; glycogen synthase kinase 3β ; MEFs ; mouse embryonic fibroblast cells ; ConA ; concanavalin A ; LPS ; lipopolysaccharide ; PKD2 ; protein kinase D2 ; mGluRs ; metabotropic glutamate receptors ; DHPG ; (S)-3 ; 5-dihydroxyphenylglycine ; DARPP-32 ; dopamine and cAMP-regulated phosphoprotein ; MAP1A ; microtubule associated protein 1A ; CLS ; centrosome localiz

刊名：Cellular Signalling

出版年：2017

6.Effects of GRASP variation on memory in psychiatrically healthy individuals and cognitive dysfunction in schizophrenics

作者：Natalie Matosin^a ; ^b ; ^c ; ^d ; Melissa J. Green^a ; ^c ; ^f ; Kelly A. Newell^a ; ^b ; Francesca Fernandez-Enright^a ; ^b ; ^e ; ^{francesca.fernandez@acu.edu.au}

关键词：GRASP ; general receptor for phosphoinositides-1-associated scaffold protein ; SNP ; single nucleotide polymorphism ; CD ; cognitive deficits ; CS ; cognitively spared ; PSD ; postsynaptic density ; NMDARs ; N-methyl-d-aspartate receptors ; AMPARs ; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors ; GABA ; gamma aminobutyric acid ; mGluR1/5 ; metabotropic glutamate receptors 1 and 5 ; ECS ; electroconvulsive shock therapy ; 5&prime ; UTR ; 5&prime ; untranslated region ; DIP ; diagnostic interview for psyc

刊名：Gene Reports

出版年：2017

7.Effects of Group I metabotropic glutamate receptor antagonists on sensitivity to reinforcer magnitude and delayed reinforcement in a delay-discounting task in rats: Contribution of delay presentation order

作者：Justin R. Yates ; ^{yatesj1@nku.edu} ; Katherine K. Rogers ; Benjamin T. Gunkel ; Nicholas A. Prior ; Mallory N. Hughes ; Sara M. Sharpe ; Hunter L. Campbell ; Anthony B. Johnson ; Margaret G. Keller ; Kerry A. Breitenstein ; Hansen N. Shults

关键词：Impulsive choice ; Delay discounting ; Sensitivity to delayed reinforcement ; Sensitivity to reinforcer magnitude ; Metabotropic glutamate receptor ; Rat

刊名：Behavioural Brain Research

出版年：2017

8.Off-target potential of AMN082 on sleep EEG and related physiological variables: Evidence from mGluR7 (−/−) mice

作者：A. Ahnaou ; ^{aahnaou@its.jnj.com" class="auth_mail" title="E-mail the corresponding author} ; L. Raeyemaekers ; H. Huysmans ; W.H.I.M. Drinkenburg

关键词：Glutamate ; mGluR7 ; AMN082 ; Rats ; mGluR7 (&minus ; /&minus ; ) mice ; Off-target ; Sleep-wake cycle ; EEG oscillations ; Body temperature ; Locomotor activity ; Psychiatric and neurodegenerative disorders

刊名：Behavioural Brain Research

出版年：2016

9.7TM X-ray structures for class C GPCRs as new drug-discovery tools. 1. mGluR5

作者：Sid Topiol ; ^{Sid.Topiol@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Michael Sabio

关键词：Structure-based drug design ; Computer-aided drug discovery ; Metabotropic glutamate receptors (mGluRs) ; Mavoglurant ; Docking ; X-ray structure ; Negative allosteric modulators (NAMs) ; Positive allosteric modulators (PAMs)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.mGlu5 receptor antagonist blocks bromocriptine-induced conditioned place preference in bilateral mesolimbic-lesioned rat

作者：Omar Ouachikh^a ; Carine Chassain^a ; ^b ; Guilhem Pagè ; s^c ; Franck Durif^a ; ^b ; Aziz Hafidi^a ; ^{azhafidi@univ-bpclermont.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Conditioned place preference ; 6-OHDA ; Parkinson ; Reward

刊名：Behavioural Brain Research

出版年：2017

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