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在“Elsevier电子期刊”中，命中：1,216条，耗时：小于0.01 秒

1.Differential diagnosis of atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: utility of p16 in combination with MDM2 and CDK4 immunohistochemistry

作者：Solè ; ne-Florence Kammerer-Jacquet ; MD^a ; ^b ; ^{jacquet.sf@gmail.com} ; Sixte Thierry ; MBBS^a ; Florian Cabillic ; PharmD ; PhD^c ; ^d ; Morgane Lannes ; MBBS^e ; Florence Burtin ; MD^a ; Sé ; bastien Henno ; MD^a ; Fré ; dé ; ric Dugay ; PharmD ; PhD^b ; ^c ; Guillaume Bouzillé ; MD^f ; ^g ; Nathalie Rioux-Leclercq ; MD ; PhD^a ; ^b ; Marc-Antoine Belaud-Rotureau ; PharmD ; PhD^b ; ^c ; Nathalie Stock ; MD^a

关键词：Well-differentiated/dedifferentiated liposarcoma ; Differential diagnosis ; p16 ; MDM2 ; CDK4 ; Immunohistochemistry ; Fluorescence in situ hybridization

刊名：Human Pathology

出版年：2017

2.Design, synthesis and structure-activity relationship of 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-ones as potent p53-MDM2 inhibitors

作者：Wei-Huang Zhou^a ; ^b ; Xi-Guo Xu^a ; ^b ; Jin Li^b ; Xiao Min^b ; Jian-Zhong Yao^b ; Guo-Qiang Dong^b ; Chun-Lin Zhuang^b ; ^{zclnathan@163.com} ; Zhen-Yuan Miao^b ; ^{miaozhenyuan@hotmail.com} ; Wan-Nian Zhang^a ; ^b ; ^{zhangwnk@hotmail.com}

关键词：p53-MDM2 ; Protein&ndash ; protein interaction ; Inhibitors ; Drug design ; Structure&ndash ; activity relationships ; Antiproliferative

刊名：Chinese Chemical Letters

出版年：2017

3.Protection against High-Fat-Diet-Induced Obesity in MDM2^C305F Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure

作者：Shijie Liu¹ ; ² ; ⁵ ; Tae-Hyung Kim¹ ; ² ; ⁵ ; Derek A. Franklin¹ ; ² ; ³ ; Yanping Zhang¹ ; ² ; ³ ; ⁴ ; ⁶ ; ^{ypzhang@med.unc.edu}

关键词：ribosomal protein ; MDM2 ; p53 ; high-fat diet ; NAD+ ; energy expenditure

刊名：Cell Reports

出版年：2017

4.LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer

作者：Wen Zhang ; Ting Zhong ; Yun Chen ; ^{ychen@njmu.edu.cn}

关键词：p53 ; MDM2 ; Protein-protein interaction ; Quantitative targeted proteomics ; Breast cancer

刊名：Journal of Proteomics

出版年：2017

5.The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2

作者：Shirly Lahav-Baratz^a ; ¹ ; ^{lahav_shirly@clalit.org.il} ; Yelena Kravtsova-Ivantsiv^b ; ¹ ; Shay Golan^c ; Aaron Ciechanover^b

关键词：DUB ; Male infertility ; Mdm2 ; Spermatozoa ; USP26

刊名：Biochemical and Biophysical Research Communications

出版年：2017

6.Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction

作者：Ewa Surmiak^a ; Constantinos G. Neochoritis^b ; Bogdan Musielak^a ; Aleksandra Twarda-Clapa^c ; ^d ; Katarzyna Kurpiewska^a ; Grzegorz Dubin^c ; ^d ; Carlos Camacho^e ; Tad A. Holak^a ; ^d ; Alexander Dö ; mling^b ; ^{a.s.s.domling@rug.nl}

刊名：European Journal of Medicinal Chemistry

出版年：2017

7.Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis

作者：James A. McCubrey^a ; ^{mccubreyj@ecu.edu} ; Kvin Lertpiriyapong^b ; Timothy L. Fitzgerald^c ; Alberto M. Martelli^d ; Lucio Cocco^d ; Dariusz Rakus^e ; Agnieszka Gizak^e ; Massimo Libra^f ; Melchiorre Cervello^g ; Guiseppe Montalto^h ; Li V. Yangⁱ ; Stephen L. Abrams^a ; Linda S. Steelman^a

关键词：TP53 ; miRs ; MDM2 ; Nutlin-3 chemosensitivity ; Cellular senescence ; Invasion ; Metastasis

刊名：Advances in Biological Regulation

出版年：2017

8.Discovery of novel polycyclic spiro-fused carbocyclicoxindole-based anticancer agents

作者：Lidan Zhang^a ; ¹ ; Wen Ren^a ; ¹ ; Xiaoyan Wang^c ; Jiaying Zhang^d ; Jie Liu^a ; ^{liujie2011@scu.edu.cn} ; Lifeng Zhao^b ; ^{lifengzhao@scu.edu.cn} ; Xia Zhang^a ; ^{zhang-xia@scu.edu.cn}

关键词：Polycyclic spiro-fused carbocyclicoxindoles ; Antiproliferative activity ; p53 inducer ; MDM2

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.On p53 revival using system oriented drug dosage design

作者：Muhammad Haseeb^a ; ^d ; ^{haseeb3389@hotmail.com} ; Shumaila Azam^a ; A.I. Bhatti^b ; ^{aamer987@gmail.com} ; Rizwan Azam^b ; Mukhtar Ullah^c ; Sahar Fazal^a

关键词：p53 ; Mdm2 ; Cancer ; Nutlin ; PBK

刊名：Journal of Theoretical Biology

出版年：2017

10.Genome-scale functional analysis of the human genes modulating p53 activity by regulating MDM2 expression in a p53-independent manner

作者：Dong Min Kim^a ; Seung-Hyun Choi^b ; Young Il Yeom^c ; Sang-Hyun Min^d ; ^{shmin03@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Il-Chul Kim^e ; ^{ickim@chonnam.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：High-throughput screening ; MDM2 ; p53 ; Leukemia ; MDM2-modulating gene

刊名：Biochemical and Biophysical Research Communications

出版年：2016

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