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在“Elsevier电子期刊”中，命中：23条，耗时：0.0179871 秒

在所有数据库中总计命中：7条

1.A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A

作者：William A. Harrell Jr.^a ; ^d ; Rebecca C. Vieira^a ; ^e ; Susan M. Ensel^b ; Vicki Montgomery^a ; Rebecca Guernieri^a ; Vanessa S. Eccard^a ; ^f ; Yvette Campbell^a ; Virginia Roxas-Duncan^a ; ^g ; John H. Cardellina II^a ; ^h ; Robert P. Webb^a ; ^{robert.p.webb6.civ@mail.mil} ; Leonard A. Smith^c

关键词：BoNTs ; botulinum neurotoxins ; BoNT/A ; botulinum neurotoxin serotype A ; HC ; heavy chain ; LC ; light chain ; SNARE ; soluble N-ethylmaleimide-sensitive factor attachment protein receptor ; SNAP-25 ; 25 ; kDa synaptosomal-associated protein ; BIG-IV ; Botulism Immune Globulin Intravenous (Human) ; SAR ; structure-activity relationship ; IC50 ; 50% inhibitory concentration ; MPNHDA ; mouse phrenic nerve hemidiaphragm assay

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Reversal of BoNT/A-mediated inhibition of muscle paralysis by 3,4-diaminopyridine and roscovitine in mouse phrenic nerve-hemidiaphragm preparations

作者：Michael Adler^a ; ^b ; ^{michael.adler2@us.army.mil} ; ^{miklos78@hotmail.com} ; Sharad S. Deshpande^a ; James P. Apland^a ; Bridget Murray^a ; Andrew Borrell^a

关键词：Botulinum neurotoxin ; 3 ; 4-Diaminopyridine ; Roscovitine ; Acetylcholine ; Mouse ; Diaphragm muscle ; Aminopyridine ; Potassium channel blocker ; Calcium channel agonist ; Bioterrorism

刊名：Neurochemistry International

出版年：2012

3.Scorpion toxins for the reversal of BoNT-induced paralysis

作者：Colin A. Lowery ; Michael Adler ; Andrew Borrell ; Kim D. Ja

关键词：Botulinum neurotoxin ; Scorpion toxin ; Bioterrorism ; Aminopyridine ; Phrenic nerve hemidiaphragm

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：15 December, 2013

4.Phrenic nerve-hemidiaphragm as a highly sensitive replacement assay for determination of functional botulinum toxin antibodies

作者：C. Rasetti-Escargueil ; ^a ; ^{Christine.escargueil@nibsc.hpa.org.uk"" rel=""nofollow} ; Y. Liu^a ; P. Rigsby^a ; R.G.A. Jones^a ; D. Sesardic^a

关键词：Botulinum neurotoxin ; Paralysis ; Phrenic nerve-hemidiaphragm ; Ex vivo ; In vivo ; Antibodies ; Assays

刊名：Toxicon

出版年：2011

5.Botulinum type A2 neurotoxin (150 kDa) is stronger than type A1 progenitor toxin (900 kDa) in the inhibition activity of neuromuscular transmission of isolated mouse phrenic nerve-hemidiaphragm

作者：Kiyota Naotoshi ; Sugimoto Nakaba ; Nagano Ayataka ; Nakahira Shinji ; Harakawa Tetsuhiro ; Ginnaga Akihiro

关键词：NTX ; Mouse phrenic nerve– ; hemidiaphragm

刊名：Toxicon

出版年：2008

6.Measurement of botulinum types A, B and E neurotoxicity using the phrenic nerve–hemidiaphragm: Improved precision with in-bred mice

作者：C. Rasetti-Escargueil ; R.G.A. Jones ; Y. Liu ; D. Sesardic

关键词：Botulinum neurotoxin ; Paralysis ; Mouse ; Phrenic nerve– ; hemidiaphragm

刊名：Toxicon

出版年：2009

7.Detection of biologically active botulinum neurotoxin-A in serum using high-throughput FRET-assay

作者：Suresh G. Joshi ; ^{suresh.joshi@drexelmed.edu}

关键词：AFU ; arbitrary fluorescing units ; BoNTA ; botulinum neurotoxin-A ; ELISA ; enzyme-linked immunosorbent assay ; FL ; full-length ; FRET ; fluorescent resonance energy transfer ; LCA ; light chain of BoNTA ; LCA ; light-chain-A ; MPB ; mouse protection bioassay ; SNAP-25

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2012

8.The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors

作者：Marjana Grandi?^a ; Romulo Ará ; oz^b ; Jordi Molgó ; ^b ; Tom Turk^c ; Kristina Sep?i?^c ; Evelyne Benoit^b ; Robert Frange?^a ; ^{robert.frangez@vf.uni-lj.si}

关键词：APS12-2 ; Neuromuscular junction ; Nicotinic acetylcholine receptors ; Xenopus oocytes ; AChE inhibitors ; Torpedo marmorata ; Motor endplate

刊名：Toxicology and Applied Pharmacology

出版年：2012

9.Muscle force and acetylcholinesterase activity in mouse hemidiaphragms exposed to paraoxon and treated by oximes in vitro

作者：Horst Thiermann ; Peter Eyer ; Franz Worek

关键词：Muscle force ; Diaphragm ; Paraoxon ; Organophosphate ; Oximes

刊名：Toxicology

出版年：2010

10.Comparison of effects of botulinum toxin subtype A1 and A2 using twitch tension assay and rat grip strength test

作者：Yasushi Torii^a ; ^{torii-ya@kaketsuken.or.jp} ; Naotoshi Kiyota^a ; Nakaba Sugimoto^b ; Yuichiro Mori^a ; Yoshitaka Goto^a ; Tetsuhiro Harakawa^a ; Shinji Nakahira^a ; Ryuji Kaji^c ; Shunji Kozaki^d ; Akihiro Ginnaga^a

关键词：Botulinum toxin ; Twitch tension ; Grip strength

刊名：Toxicon

出版年：2011

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