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在“Elsevier电子期刊”中，命中：575条，耗时：0.1539266 秒

在所有数据库中总计命中：1,028条

1.Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA

作者：Xiquan Liang ; Jason Potter ; ^{jason.potter@thermofisher.com} ; Shantanu Kumar ; Namritha Ravinder ; Jonathan D. Chesnut

关键词：CRISPR ; clustered regularly interspaced short palindromic repeats ; CAS9 ; CRISPR associated protein ; gRNA ; guide RNA ; PAM ; protospacer adjacent motif ; RNP ; ribonucleoprotein ; HDR ; homology directed repair ; hESCs ; human embryonic stem cells ; NHEJ ; non-homologous end joining ; SNP ; single-nucleotide polymorphism

刊名：Journal of Biotechnology

出版年：2017

2.Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine

作者：L. van Andel^a ; ^{l.v.andel@nki.nl} ; Z. Zhang^b ; S. Lu^b ; V. Kansra^b ; S. Agarwal^b ; L. Hughes^b ; M.M. Tibben^a ; A. Gebretensae^a ; H. Rosing^a ; J.H.M. Schellens^c ; ^d ; J.H. Beijnen^a ; ^d

关键词：ACN ; acetonitrile ; BER ; base excision repair ; C.V. ; coefficient of variation ; DMSO ; dimethylsulfoxide ; DSB ; double strand break ; EMA ; European Medicine Agency ; FDA ; Food and Drug Administration ; GLP ; Good Laboratory Practice ; HRR ; homologous recombination repair ; IS ; internal standard ; LC&ndash ; MS/MS ; liquid chromatography &ndash ; tandem mass spectrometry ; LLOQ ; lower limit of quantification ; MeOH ; methanol ; MF ; matrix factor ; MRM ; multiple reaction monitoring ; NHEJ ; non-homologous end joining

刊名：Journal of Chromatography B

出版年：2017

3.DNA damage, repair monitoring and epigenetic DNA methylation changes in seedlings of Chernobyl soybeans

作者：Mariyana Georgieva^a ; ^b ; ^{mimy80@abv.bg} ; Namik M. Rashydov^c ; Martin Hajduch^a

关键词：CNPP ; Chernobyl nuclear power plant ; IR ; ionizing radiation ; ROS ; reactive oxygen species ; SSBs ; single strand breaks ; DSBs ; double strand breaks ; R-C ; radio-contaminated ; DMSO ; dimethyl sulfoxide ; N/N ; neutral unwinding/neutral electrophoresis ; A/N ; alkaline unwinding/neutral electrophoresis ; A/A ; alkaline unwinding/alkaline electrophoresis ; SE ; standard errors ; SD ; standard deviation ; SNK ; Student-Newman-Keuls test ; ALS ; alkali-labile sites ; NHEJ ; non-homologous end joining

刊名：DNA Repair

出版年：2017

4.The non-homologous end-joining pathway of S. cerevisiae works effectively in G1-phase cells, and religates cognate ends correctly and non-randomly

作者：Shujuan Gao^a ; Sangeet Honey^b ; Bruce Futcher^b ; ^{bfutcher@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Arthur P. Grollman^a

关键词：Double strand breaks ; Non-homologous end-joining ; DSBs ; NHEJ ; G1-phase ; Cell cycle ; Yeast ; Karyotype ; Translocation

刊名：DNA Repair

出版年：2016

5.Clinicopathological and molecular characteristics of Ku 70/80 expression in Nigerian breast cancer and its potential therapeutic implications

作者：Ayodeji O.J. Agboola^a ; ^{Johndeji2001@yahoo.co.uk} ; ^{johnson.agboola@oouagoiwoye.edu.ng} ; Henry O. Ebili^a ; Victoria O. Iyawe^a ; Adekunbiola A.F. Banjo^a ; Babatunde A. Salami^b ; Emad A. Rakha^c ; Chrstopher C. Nolan^c ; Ian O. Ellis^c ; Andrew R. Green^c

关键词：Nigerian breast cancer ; Ku 70/80 ; Clinicopathological ; Biological ; Prognosis

刊名：Pathology - Research and Practice

出版年：2017

6.Helicobacter pylori-induced chronic inflammation causes telomere shortening of gastric mucosa by promoting PARP-1-mediated non-homologous end joining of DNA

作者：Wei-Ping Lee^a ; ^e ; ^{wplee@vghtpe.gov.tw" class="auth_mail" title="E-mail the corresponding author} ; Ming-Chih Hou^b ; ^c ; Keng-Hsin Lan^c ; Chung-Pin Li^c ; Yee Chao^d ; Han-Chieh Lin^c ; Shou-Dong Lee^c

关键词：Helicobacter pylori ; Telomere ; PARP-1 ; Non-homologous end joining ; Reactive oxygen species

刊名：Archives of Biochemistry and Biophysics

出版年：2016

7.DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer

作者：Catherine R. Sears^a ; ^{crufatto@iu.edu" class="auth_mail" title="E-mail the corresponding author} ; Sean A. Cooney^b ; Helen Chin-Sinex^c ; Marc S. Mendonca^c ; ^d ; John J. Turchi^a ; ^e

关键词：NSCLC ; non-small cell lung cancer ; CDDP ; cisplatin ; IR ; ionizing radiation ; CDDP-IR ; combination treatment with cisplatin followed by ionizing radiation ; DDR ; DNA damage response ; DSB ; double strand break ; NER ; nucleotide excision repair ; HRR ; homologous recombination repair ; NHEJ ; non-homologous end-joining ; Gy ; Gray

刊名：DNA Repair

出版年：2016

8.End-processing nucleases and phosphodiesterases: An elite supporting cast for the non-homologous end joining pathway of DNA double-strand break repair

作者：Vijay Menon^a ; Lawrence F. Povirk^a ; ^b ; ^{lpovirk@vcu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：DNA double-strand break repair ; End-processing ; Nucleases ; Phosphodiesterases

刊名：DNA Repair

出版年：2016

9.Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances

作者：James M. Wagner^a ; Hal S. Alper^a ; ^b ; ^{halper@che.utexas.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ARS ; autonomously replicating sequence ; CEN ; centromere ; CRISPR ; Clustered ; Regularly Interspaced ; Short Palindromic Repeats ; DSB ; double strand break ; GFP ; green fluorescent protein ; GRAS ; Generally Regarded As Safe ; gRNA ; guide RNA (for CRISPR) ; HR ; homologous recombination ; IRES ; internal ribosomal entry site ; FDA ; Food and Drug Administration ; NHEJ ; non-homologous end-joining ; RNAi ; RNA interference ; RNAP II/III ; RNA polymerase II/III ; TALEN ; transcription activator-like effector nuclease ; T

刊名：Fungal Genetics and Biology

出版年：2016

10.The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining

作者：Younghyun Lee^a ; Huizi Keiko Li^a ; ^b ; Aya Masaoka^a ; Shigeaki Sunada^a ; ^c ; Hirokazu Hirakawa^a ; Akira Fujimori^a ; Jac A. Nickoloff^d ; Ryuichi Okayasu^a ; ^{okayasu.ryuichi@qst.go.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：PU-H71 ; Hsp90 ; Heavy ion radiotherapy ; Radiosensitization ; DNA repair

刊名：Radiotherapy and Oncology

出版年：2016

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