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在“Elsevier电子期刊”中，命中：1,320条，耗时：0.123948 秒

在所有数据库中总计命中：14,264条

1.Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents

作者：Roheeth Kumar Pavana^a ; Shruti Choudhary^a ; Anja Bastian^b ; Michael A. Ihnat^c ; Ruoli Bai^d ; Ernest Hamel^d ; Aleem Gangjee^a ; ^{gangjee@duq.edu}

关键词：AA ; antiangiogenic agents ; MTA ; microtubule targeting agents ; VEGFR-2 ; vascular endothelial growth factor receptor-2 ; PDGFR-β ; platelet-derived growth factor receptor-β ; CAM ; chorioallantoic membrane ; CA ; combretastatin A-4 ; Pgp ; P-glycoprotein ; EGFR ; epidermal growth factor receptor ; TBS ; Tris-buffered saline ; HRP ; horseradish peroxidase ; PY ; phosphotyrosine

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

3.Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond

作者：Mary Nakazawa ; Natasha Kyprianou ; ^{nkypr2@uky.edu}

关键词：ADT ; Androgen deprivation therapy ; AR ; Androgen receptor ; CRPC ; Castration resistant prostate cancer ; DHT ; Dihydrotestosterone ; EGF ; Epidermal growth factor ; EMT ; Epithelial mesenchymal transition ; ERβ ; Estrogen receptor β ; FGF ; Fibroblast growth factor ; IGF ; Insulin-like growth factor ; MET ; Mesenchymal epithelial transition ; PDGF ; Platelet derived growth factor ; PI3 K ; Phosphatidylinositol 3-OH kinase ; PTEN ; Phosphatase tensin homolog ; RTK ; Receptor tyrosine kinase ; SHH ; Sonic Hedgehog ; TGFβ ; T

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

4.The anti-ALS drug riluzole attenuates pericyte loss in the diabetic retinopathy of streptozotocin-treated mice

作者：Jeong A. Choi^a ; ¹ ; Yoo-Ri Chung^b ; ¹ ; ² ; Hyae-Ran Byun^a ; ³ ; Hwangseo Park^d ; Jae-Young Koh^a ; ^c ; ^{jkko@amc.seoul.kr} ; Young Hee Yoon^b ; ^{yhyoon@amc.seoul.kr}

关键词：AGE ; advanced glycation end products ; BRB ; blood-retinal barrier ; BSA ; bovine serum albumin ; DR ; diabetic retinopathy ; FBS ; fetal bovine serum ; FITC ; fluorescein isothiocyanate ; mLDL ; modified low-density lipoprotein ; MCP1 ; monocyte chemoattractant protein-1 ; NPDR ; nonproliferative diabetic retinopathy ; PBS ; phosphate-buffered saline ; PDGF ; platelet-derived growth factor ; PDGFR-β ; platelet-derived growth factor receptor-β ; PDR ; proliferative diabetic retinopathy ; PKC ; protein kinase C ; STZ ; stre

刊名：Toxicology and Applied Pharmacology

出版年：2017

5.TMDOCK: An Energy-Based Method for Modeling α-Helical Dimers in Membranes

作者：Andrei L. Lomize ; ^{almz@umich.edu} ; Irina D. Pogozheva

关键词：3D ; three-dimensional ; APP ; amyloid precursor protein ; Eph ; ephrin receptor ; EFDOCK-TM ; Evolutionary-guided Fold and Dock of TransMembrane proteins ; FGFR ; fibroblast growth factor receptor ; FMAP ; folding of membrane-associated peptides ; MD ; molecular dynamics ; MM ; molecular mechanics ; PDGFRB ; platelet derived growth factor receptor beta ; PDB ; Protein Data Bank ; PPM ; Positioning of Proteins in Membranes ; RTK ; receptor tyrosine kinase ; TM ; transmembrane ; VEGFR ; vascular endothelial growth factor r

刊名：Journal of Molecular Biology

出版年：2017

6.Expression and activation of platelet-derived growth factor β receptor, mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) in canine mammary tumours

作者：Gennaro Altamura^a ; ^{gennaro.altamura@unina.it} ; Barbara degli Uberti^b ; ^{barbara.degliuberti@cert.izsmportici.it} ; Giorgio Galiero^b ; ^{giorgio.galiero@cert.izsmportici.it} ; Manuela Martano^a ; ^{manuela.martano@unina.it} ; Antonella Pirro^a ; ^{divas3@hotmal.it} ; Marco Russo^a ; ^{marco.russo@unina.it} ; Giuseppe Borzacchiello^a ; ^{borzacch@unina.it}

关键词：PDGFβR ; MEK ; ERK ; TKR inhibitors ; Oncology

刊名：Research in Veterinary Science

出版年：2017

7.Platelet-derived growth factor receptors (PDGFRs) fusion genes involvement in hematological malignancies

作者：Kwaku Appiah-Kubi^a ; ^c ; ^{kappiah@uds.ed.gh} ; Ting Lan^a ; Ying Wang^a ; Hai Qian^a ; Min Wu^a ; Xiaoyuan Yao^b ; Yan Wu^a ; Yongchang Chen^a ; ^{ycchen54@ujs.edu.cn}

关键词：PDGFRs ; Fusion genes ; Myeloid neoplasm ; Lymphoid neoplasm ; Chromosomal translocation

刊名：Critical Reviews in Oncology/Hematology

出版年：2017

8.Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis

作者：Ana E. Carvajal ; Marí ; a D. Vá ; zquez-Carretero ; Pablo Garcí ; a-Miranda ; Marí ; a J. Peral ; Marí ; a L. Calonge ; ^{calonge@us.es} ; Anunciació ; n A. Ilundain

关键词：α-SMA ; α-smooth muscle actin ; ApoER2 ; apolipoprotein E receptor 2 ; CASK ; calcium/calmodulin-dependent serine protein kinase ; Dab1 ; Disabled-1 ; DSS ; dextran sulphate sodium ; DNMT1 ; (DNA (Cytosine-5-)-Methyltransferase 1) ; IL-1β ; interleukin-1β ; PDGF-BB ; platelet derived growth factor β ; TGF-β1 ; transforming growth factor β1 ; TNF-α ; tumour necrosis factor α ; Sp1 ; transcription factor Sp1 ; Tbr1 ; T-box brain 1 ; VLDLR ; very low-density lipoprotein receptor

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

9.The GABA_B positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABA_B receptors

作者：Maria C. Olianas ; ^{molianas@unica.it} ; Simona Dedoni ; Pierluigi Onali

关键词：CGP7930 (PubChem CID ; 5024764) ; GS39783 (PubChem CID ; 6604928) ; (-)-baclofen (PubChem CID ; 44602) ; SKF97541 (PubChem CID ; 5230) ; CGP55845 (PubChem CID ; 5311042) ; CGP54626 (PubChem CID ; 197584) ; phorbol 12-myristate 13 acetate (PubChem CID ; 27924) ; Go 6850 (PubChem CID ; 2396) ; 5Z-7-oxozeaenol (PubChem CID ; 9863776) ; GW5074 (PubChem CID ; 5924208)

刊名：European Journal of Pharmacology

出版年：2017

10.Receptor Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders

作者：Katelyn N. Nelson¹ ; Malalage N. Peiris¹ ; April N. Meyer¹ ; Asma Siari² ; Daniel J. Donoghue¹ ; ³ ; ^{ddonoghue@ucsd.edu}

关键词：leukemia ; lymphoma ; oncogenic fusion ; ALK ; FGFR ; PDGFR.

刊名：Trends in Molecular Medicine

出版年：2017

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