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Springer电子图书(3)
CNKI学位论文(11299)
CNKI期刊论文0611(3)
知网期刊论文(2959)
在“
Elsevier电子期刊
”中,
命中:
1,320
条,耗时:0.123948 秒
在所有数据库中总计命中:
14,264
条
1.
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents
作者:
Roheeth Kumar Pavana
a
;
Shruti Choudhary
a
;
Anja Bastian
b
;
Michael A. Ihnat
c
;
Ruoli Bai
d
;
Ernest Hamel
d
;
Aleem Gangjee
a
;
gangjee@duq.edu
关键词:
AA
;
antiangiogenic agents
;
MTA
;
microtubule targeting agents
;
VEGFR-2
;
vascular endothelial
growth
factor
receptor
-2
;
PDGFR-β
;
platelet
-
derived
growth
factor
receptor
-β
;
CAM
;
chorioallantoic membrane
;
CA
;
combretastatin A-4
;
Pgp
;
P-glycoprotein
;
EGFR
;
epidermal
growth
factor
receptor
;
TBS
;
Tris-buffered saline
;
HRP
;
horseradish peroxidase
;
PY
;
phosphotyrosine
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
The marine-
derived
pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR
作者:
Mohamed M. Mohyeldin
mohyelmm@warhawks.ulm.edu
;
Mohamed R. Akl
mohamedreda_pharmacy@yahoo.com
;
Abu Bakar Siddique
;
Hossam M. Hassan
1
;
abuh20050@yahoo.com
;
Khalid A. El Sayed
;
elsayed@ulm.edu
关键词:
ATCC
;
American type culture collection
;
CD30
;
cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF
receptor
superfamily
;
CD31
;
platelet
endothelial cell adhesion molecule 1
;
EGF
;
epidermal
growth
factor
;
EPHB4
;
ephrin type-B
receptor
4
;
ERK
;
extracellular signal-regulated kinase
;
FGFR
;
fibroblast
growth
factor
receptor
;
FLT3
;
fms-related tyrosine kinase 3
;
JAK2
;
janus kinase 2
;
L858R
;
leucine 858 mutated to arginine
;
L861Q
;
leucine 861 mutated to glutamine
;
M
;
m
刊名:Biochemical Pharmacology
出版年:2017
3.
Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond
作者:
Mary Nakazawa
;
Natasha Kyprianou
;
nkypr2@uky.edu
关键词:
ADT
;
Androgen deprivation therapy
;
AR
;
Androgen
receptor
;
CRPC
;
Castration resistant prostate cancer
;
DHT
;
Dihydrotestosterone
;
EGF
;
Epidermal
growth
factor
;
EMT
;
Epithelial mesenchymal transition
;
ERβ
;
Estrogen
receptor
β
;
FGF
;
Fibroblast
growth
factor
;
IGF
;
Insulin-like
growth
factor
;
MET
;
Mesenchymal epithelial transition
;
PDGF
;
Platelet
derived
growth
factor
;
PI3 K
;
Phosphatidylinositol 3-OH kinase
;
PTEN
;
Phosphatase tensin homolog
;
RTK
;
Receptor
tyrosine kinase
;
SHH
;
Sonic Hedgehog
;
TGFβ
;
T
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
4.
The anti-ALS drug riluzole attenuates pericyte loss in the diabetic retinopathy of streptozotocin-treated mice
作者:
Jeong A. Choi
a
;
1
;
Yoo-Ri Chung
b
;
1
;
2
;
Hyae-Ran Byun
a
;
3
;
Hwangseo Park
d
;
Jae-Young Koh
a
;
c
;
jkko@amc.seoul.kr
;
Young Hee Yoon
b
;
yhyoon@amc.seoul.kr
关键词:
AGE
;
advanced glycation end products
;
BRB
;
blood-retinal barrier
;
BSA
;
bovine serum albumin
;
DR
;
diabetic retinopathy
;
FBS
;
fetal bovine serum
;
FITC
;
fluorescein isothiocyanate
;
mLDL
;
modified low-density lipoprotein
;
MCP1
;
monocyte chemoattractant protein-1
;
NPDR
;
nonproliferative diabetic retinopathy
;
PBS
;
phosphate-buffered saline
;
PDGF
;
platelet
-
derived
growth
factor
;
PDGFR-β
;
platelet
-
derived
growth
factor
receptor
-β
;
PDR
;
proliferative diabetic retinopathy
;
PKC
;
protein kinase C
;
STZ
;
stre
刊名:Toxicology and Applied Pharmacology
出版年:2017
5.
TMDOCK: An Energy-Based Method for Modeling α-Helical Dimers in Membranes
作者:
Andrei L. Lomize
;
almz@umich.edu
;
Irina D. Pogozheva
关键词:
3D
;
three-dimensional
;
APP
;
amyloid precursor protein
;
Eph
;
ephrin
receptor
;
EFDOCK-TM
;
Evolutionary-guided Fold and Dock of TransMembrane proteins
;
FGFR
;
fibroblast
growth
factor
receptor
;
FMAP
;
folding of membrane-associated peptides
;
MD
;
molecular dynamics
;
MM
;
molecular mechanics
;
PDGFRB
;
platelet
derived
growth
factor
receptor
beta
;
PDB
;
Protein Data Bank
;
PPM
;
Positioning of Proteins in Membranes
;
RTK
;
receptor
tyrosine kinase
;
TM
;
transmembrane
;
VEGFR
;
vascular endothelial
growth
factor
r
刊名:Journal of Molecular Biology
出版年:2017
6.
Expression and activation of
platelet
-
derived
growth
factor
β
receptor
, mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) in canine mammary tumours
作者:
Gennaro Altamura
a
;
gennaro.altamura@unina.it
;
Barbara degli Uberti
b
;
barbara.degliuberti@cert.izsmportici.it
;
Giorgio Galiero
b
;
giorgio.galiero@cert.izsmportici.it
;
Manuela Martano
a
;
manuela.martano@unina.it
;
Antonella Pirro
a
;
divas3@hotmal.it
;
Marco Russo
a
;
marco.russo@unina.it
;
Giuseppe Borzacchiello
a
;
borzacch@unina.it
关键词:
PDGFβR
;
MEK
;
ERK
;
TKR inhibitors
;
Oncology
刊名:Research in Veterinary Science
出版年:2017
7.
Platelet
-
derived
growth
factor
receptor
s (PDGFRs) fusion genes involvement in hematological malignancies
作者:
Kwaku Appiah-Kubi
a
;
c
;
kappiah@uds.ed.gh
;
Ting Lan
a
;
Ying Wang
a
;
Hai Qian
a
;
Min Wu
a
;
Xiaoyuan Yao
b
;
Yan Wu
a
;
Yongchang Chen
a
;
ycchen54@ujs.edu.cn
关键词:
PDGFRs
;
Fusion genes
;
Myeloid neoplasm
;
Lymphoid neoplasm
;
Chromosomal translocation
刊名:Critical Reviews in Oncology/Hematology
出版年:2017
8.
Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis
作者:
Ana E. Carvajal
;
Marí
;
a D. Vá
;
zquez-Carretero
;
Pablo Garcí
;
a-Miranda
;
Marí
;
a J. Peral
;
Marí
;
a L. Calonge
;
calonge@us.es
;
Anunciació
;
n A. Ilundain
关键词:
α-SMA
;
α-smooth muscle actin
;
ApoER2
;
apolipoprotein E
receptor
2
;
CASK
;
calcium/calmodulin-dependent serine protein kinase
;
Dab1
;
Disabled-1
;
DSS
;
dextran sulphate sodium
;
DNMT1
;
(DNA (Cytosine-5-)-Methyltransferase 1)
;
IL-1β
;
interleukin-1β
;
PDGF-BB
;
platelet
derived
growth
factor
β
;
TGF-β1
;
transforming
growth
factor
β1
;
TNF-α
;
tumour necrosis
factor
α
;
Sp1
;
transcription
factor
Sp1
;
Tbr1
;
T-box brain 1
;
VLDLR
;
very low-density lipoprotein
receptor
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
9.
The GABA
B
positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABA
B
receptor
s
作者:
Maria C. Olianas
;
molianas@unica.it
;
Simona Dedoni
;
Pierluigi Onali
关键词:
CGP7930 (PubChem CID
;
5024764)
;
GS39783 (PubChem CID
;
6604928)
;
(-)-baclofen (PubChem CID
;
44602)
;
SKF97541 (PubChem CID
;
5230)
;
CGP55845 (PubChem CID
;
5311042)
;
CGP54626 (PubChem CID
;
197584)
;
phorbol 12-myristate 13 acetate (PubChem CID
;
27924)
;
Go 6850 (PubChem CID
;
2396)
;
5Z-7-oxozeaenol (PubChem CID
;
9863776)
;
GW5074 (PubChem CID
;
5924208)
刊名:European Journal of Pharmacology
出版年:2017
10.
Receptor
Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders
作者:
Katelyn N. Nelson
1
;
Malalage N. Peiris
1
;
April N. Meyer
1
;
Asma Siari
2
;
Daniel J. Donoghue
1
;
3
;
ddonoghue@ucsd.edu
关键词:
leukemia
;
lymphoma
;
oncogenic fusion
;
ALK
;
FGFR
;
PDGFR.
刊名:Trends in Molecular Medicine
出版年:2017
1
2
3
4
5
6
7
8
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