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在“Elsevier电子期刊”中，命中：485条，耗时：0.032979 秒

在所有数据库中总计命中：1,118条

1.Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

作者：Alejandro Carazo^a ; Lucie Hyrsova^a ; Jan Dusek^a ; Hana Chodounska^b ; Alzbeta Horvatova^a ; Karel Berka^c ; Vaclav Bazgier^c ; Hongying Gan-Schreier^d ; Waleé ; Chamulitrat^d ; Eva Kudova^b ; Petr Pavek^a ; ^{petr.pavek@faf.cuni.cz}

关键词：BA ; bile acid ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; CYP ; cytochrome P450 ; DCA ; deoxycholic acid ; 6-ECDCA ; 6α-ethyl-chenodeoxycholic acid ; obeticholic acid ; FXR ; farnesoid X receptor ; LBD ; ligand binding domain ; LCA ; lithocholic acid ; PXR ; pregnane X receptor ; TR-FRET ; time-resolved fluorescence energy transfer ; VDR ; vitamin D receptor

刊名：Toxicology Letters

出版年：2017

2.From dioxin toxicity to putative physiologic functions of the human Ah receptor in homeostasis of stem/progenitor cells

作者：Karl Walter Bock ^{bock@uni-tuebingen.de}

关键词：AhR ; aryl hydrocarbon receptor ; PXR ; pregnane-X-receptor ; CYP ; cytochrome P450 ; UGT ; UDP-glucuronosyltranswferase ; FICZ ; 6-formylindolo[3 ; 2-b]carbazole ; ICZ ; indolo[3 ; 2-b]carbazole ; ITE ; 2-(1H--indole-3&prime ; -carbonyl)-thiazole-4-carboxylic acid methyl ester ; TCDD ; 237 ; 8-tetrachlorodibenzo-p-dioxin

刊名：Biochemical Pharmacology

出版年：2017

3.Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

作者：Saurabh G. Vispute^a ; Pengli Bu^a ; ^b ; Yuan Le^a ; Xingguo Cheng^a ; ^{chengx@stjohns.edu}

关键词：APAP ; acetaminophen ; bp ; base pair ; ChIP ; chromatin immunoprecipitation ; Cyp ; cytochrome p450 enzyme ; DEX ; dexamethasone ; Fgf21 ; fibroblast growth factor 21 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid receptor response element ; GSH ; Glutathione ; i.p. ; intraperitoneal ; NAPQI ; N-acetyl-p-benzoquinone imine ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator protein-1α ; PPAR ; peroxisome proliferator-activated receptor ; PXR ; pregnane X receptor ; TSS ; transcription start site

刊名：Toxicology

出版年：2017

4.Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

作者：Marina Vafeiadi^a ; ^bafom@uoc.gr ; Theano Roumeliotaki^a ; Georgia Chalkiadaki^a ; Panu Rantakokko^b ; Hannu Kiviranta^b ; Eleni Fthenou^a ; Soterios A. Kyrtopoulos^c ; Manolis Kogevinas^d ; ^e ; ^f ; Leda Chatzi^a

关键词：AhR ; aryl hydrocarbon receptor ; BMI ; body mass index ; BDE-47 ; tetra-bromodiphenyl ether ; CAR ; constitutive androstane receptor ; DDE ; dichlorodiphenyl dichloroethene ; DDT ; dichlorodiphenyl trichloroethane ; EDCs ; endocrine disrupting chemicals ; GDM ; gestational diabetes mellitus ; GWG ; gestational weight gain ; HCB ; hexachlorobenzene ; IOM ; Institute of Medicine ; LOQ ; limit of quantification ; PCBs ; polychlorinated biphenyls ; POPs ; persistent organic pollutants ; PXR ; pregnane X receptor ; SD ; standard

刊名：Environment International

出版年：2017

5.Molecular mechanisms of PFOA-induced toxicity in animals and humans: Implications for health risks

作者：Kan Li^a ; Peng Gao^b ; Ping Xiang^a ; Xuxiang Zhang^a ; Xinyi Cui^a ; ^{lizzycui@nju.edu.cn} ; Lena Q. Ma^a ; ^b ; ^lqma@ufl.edu

关键词：Peroxisome proliferating receptor alpha (PPARα) ; Constitutive androstane receptor (CAR) ; Pregnane-X receptor (PXR) ; Mitochondrial pathway ; Tumor necrosis factor-α/nuclear factor κB (TNF-α/NF-κB) ; Nuclear lipid hyperaccumulation

刊名：Environment International

出版年：2017

6.Role of 14-3-3 sigma in over-expression of P-gp by rifampin and paclitaxel stimulation through interaction with PXR

作者：So Won Kim^a ; ^b ; ¹ ; ^{kerorosw@gmail.com} ; Md. Hasanuzzaman^c ; ^e ; ¹ ; Munju Cho^c ; Nam Hyun Kim^a ; Hye-Young Choi^a ; Jung Woo Han^f ; Hyun June Park^g ; Ji Won Oh^h ; ⁱ ; Jae-Gook Shin^c ; ^d ; ^{phshinjg@gmail.com}

关键词：14-3-3 sigma ; Pregnane X Receptor (PXR) ; Multidrug Resistance Protein 1 (MDR1) ; Hsp90 beta ; Rifampin ; Paclitaxel

刊名：Cellular Signalling

出版年：2017

7.Differential activation of human, mouse, and rat pregnane X receptor by carnosic acid, carnosol, ursolic acid, and rosmarinic acid in rosemary extract

作者：Chun Ling Seow ; Aik Jiang Lau

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

8.SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells

作者：Huasen Tan^a ; ¹ ; Chenshu Xu^b ; ¹ ; Hang Zeng^a ; Ying Wang^a ; Yingmei Li^c ; Xiaomei Fan^a ; Pan Chen^c ; Yiming Jiang^a ; Xiao Chen^c ; Min Huang^a ; ^{huangmin@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Huichang Bi^a ; ^{bihchang@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Pregnane X receptor ; SUMOylation ; Transcriptional activity ; CYP3A4 ; P-gp

刊名：Journal of Pharmacological Sciences

出版年：2016

9.Pregnane receptor gene polymorphisms, pathogenic bacteria distribution and drug sensitivity, and TCM syndrome differentiation in patients with cholelithiasis

作者：Yi-Qiang Xie¹ ; ^# ; Jing-Zhe Zhang² ; ^# ; Hua Zhang³ ; Lei Peng⁴ ; Shuang Zhou⁵ ; Li-Zhuo Li⁴ ; Bang-Jiang Fang⁶ ; ^{fangbji@163.com" class="auth_mail" title="E-mail the corresponding author} ; Chuan-Zhu Lyu⁴ ; ^{308213740@qq.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Cholelithiasis ; Cholesterol gallstone disease ; Drug resistance test ; Pregnane X receptor ; Polymorphism ; Traditional Chinese medicine syndromes

刊名：Asian Pacific Journal of Tropical Medicine

出版年：2016

10.Involvement of ESE-3, epithelial-specific ETS factor family member 3, in transactivation of the ABCB1 gene via pregnane X receptor in intestine-derived LS180 cells but not in liver-derived HepG2 cells

作者：Naoya Kameyama ; Kaoru Kobayashi ; ^{kaoruk@faculty.chiba-u.jp" class="auth_mail" title="E-mail the corresponding author} ; Shoko Shimizu ; Yuki Yamasaki ; Mika Endo ; Mari Hashimoto ; Tomomi Furihata ; Kan Chiba

关键词：ABCB1 ; CYP3A4 ; Rifampicin ; Pregnane X receptor ; Transcription ; Induction

刊名：Drug Metabolism and Pharmacokinetics

出版年：2016

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