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在“Elsevier电子期刊”中，命中：94条，耗时：0.0509737 秒

在所有数据库中总计命中：1,356条

1.Discovery of new selective glucocorticoid receptor agonist leads

作者：Markus Berger^a ; ^{markus.berger@bayer.com} ; Hartmut Rehwinkel^a ; Norbert Schmees^a ; Heike Schä ; cke^b ; Karl Edman^c ; Lisa Wissler^c ; Andreas Reichel^d ; Stefan Jaroch^e

关键词：Glucocorticoid ; SEGRA ; Transrepression ; Transactivation ; Tetrahydronaphthalene ; Amino alcohol

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.The triterpene echinocystic acid and its 3-O-glucoside derivative are revealed as potent and selective glucocorticoid receptor agonists

作者：Demetra Georgatza^a ; ¹ ; Vyron A. Gorgogietas^a ; ¹ ; Paraskevi Kylindri^a ; Maria Ch. Charalambous^a ; Kalliope K. Papadopoulou^a ; Joseph M. Hayes^b ; Anna-Maria G. Psarra^a ; ^{ampsarra@bio.uth.gr" class="auth_mail" title="E-mail the corresponding author} ; ^{ampsarra@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：GCs ; glucocorticoids ; GR ; glucocorticoid receptor ; SEGRA ; selective glucocorticoid receptor agonist ; EA ; echinocystic acid ; EA-3G ; echinocystic acid 3-O-glucoside ; PEPCK ; phosphoenolpyruvate carboxykinase ; NF-κB ; nuclear factor kappa beta ; TNF α ; tumour necrosis factor alpha ; CMX ; mito tracker red CMXRos ; DEX ; dexamethasone ; DAC ; deacylcortivazol ; GREs ; glucocorticoid responsive elements ; LBD ; ligand binding domain ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal ; RLU ; relative luciferase units

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

3.New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity

作者：Fanny Pineau^a ; ^b ; ^c ; Geoffrey Canet^a ; ^b ; ^c ; Catherine Desrumaux^a ; ^b ; ^c ; Hazel Hunt^d ; Nathalie Chevallier^a ; ^b ; ^c ; Matthias Ollivier^a ; ^b ; ^c ; Joseph K. Belanoff^d ; Laurent Givalois^a ; ^b ; ^c ; ^{lgivalois@univ-montp2.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer's disease ; Glucocorticoid receptors ; HPA axis ; Amyloid-β peptide ; Hippocampus ; Selective GR modulator ; Aβ25&ndash ; 35 peptide ; Rat

刊名：Neurobiology of Aging

出版年：2016

4.Novel selective glucocorticoid receptor agonists (SEGRAs) with a covalent warhead for long-lasting inhibition

作者：Oksana Ryabtsova^a ; Jurgen Joossens^a ; Pieter Van Der Veken^a ; Wim Vanden Berghe^b ; Koen Augustyns^a ; Hans De Winter^a ; ^{hans.dewinter@uantwerpen.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Covalent inhibition ; Glucocorticoid receptor ; Segra ; GSK866 ; Inflammation

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

5.Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

作者：Karolien De Bosscher¹ ; Ilse M. Beck² ; Dariusz Ratman¹ ; Wim Vanden Berghe³ ; Claude Libert⁴ ; ^{Claude.Libert@irc.vib-ugent.be" class="auth_mail" title="E-mail the corresponding author}

刊名：Trends in Pharmacological Sciences

出版年：2016

6.T25: Selective glucocorticoid receptor agonists as novel anti-cancer agents

作者：E. Lesovaya^a ; ; L. Tilova^a ; O. Zadorozhnaya^a ; A. Savinkova^a ; K. Kirsanov^a ; A. Ogloblina^a ; G. Belitsky^a ; G. Baida^b ; I. Budunova^b ; M. Yakubovskaya^a

刊名：European Journal of Cancer Supplements

出版年：2015

7.P85: Synthesis and anti-cancer effects of CpdA enantiomers, non-steroidal glucocorticoid receptor ligands

作者：L. Tilova^a ; ; O. Zadorozhnaya^a ; A. Savinkova^a ; K. Kirsanov^a ; A. Ogloblina^a ; G. Belitsky^a ; I. Budunova^b ; E. Lesovaya^a ; M. Yakubovskaya^a

刊名：European Journal of Cancer Supplements

出版年：2015

8.Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention

作者：Anil Desphe ; Gang Xia ; LeeAnn J. Boerma ; Kimberly K. Vines ; Venkatram R. Atigadda ; Susan Lobo-Ruppert ; Clinton J. Grubbs ; Fariba L. Moeinpour ; Craig D. Smith ; Konstantin Christov ; Wayne J. Brouillette ; Donald D. Muccio

关键词：RXR ; retinoid X receptor ; RAR ; retinoic acid receptor ; RA ; retinoic acid ; LBD ; ligand binding domain ; IBX ; 2-iodoxybenzoic acid ; RKE ; rat kidney epithelial ; SCC ; squamous cell carcinoma ; TG ; triglycerides ; LBP ; ligand binding pocket ; THF ; tetrahydrofuran ; HMPA ; hexamethylphosphoramide ; TLC ; thin layer chromatography ; DMEM ; Dulbecco&rsquo ; s modified Eagle medium ; ER ; estrogen receptor ; GRIP-1 ; glucocorticoid receptor interacting protein-1 ; KLF4 ; Kruppel-like factor 4 ; LXRs ; liver X receptors ; NR

刊名：Bioorganic and Medicinal Chemistry

出版年：1 January, 2014

9.The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy

关键词：GCs ; glucocorticoids ; GR ; glucocorticoid receptor ; 21OH-6 ; 19OP ; 21-hydroxy-6 ; 19-epoxyprogesterone ; MKP-1 ; mitogen activated protein kinase phosphatase-1 ; COX-2 ; cyclooxygenase-2 ; BCL-XL ; B cell lymphoma factor X large

刊名：Biochemical Pharmacology

出版年：15 June 2014

10.Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists

作者：Shane Batie ; Jamie H. Lee ; Rabia A. Jama ; Drew O. Browder ; Luis A. Montano ; Chanh C. Huynh ; Lisa M. Marcus ; Dorian G. Tsosie ; Zeynab Mohammed ; Vu Trang ; Pamela A. Marshall ; Peter W. Jurutka ; ^{Peter.Jurutka@asu.edu} ; Carl E. Wagner ; ^{Carl.Wagner@asu.edu}

关键词：CM ; curcumin ; RAR ; retinoic acid receptor ; HRE ; hormone responsive element ; M2H ; mammalian two hybrid ; RXR ; retinoid X receptor ; TR ; thyroid hormone receptor ; T3 ; triiodothyronine ; VDR ; vitamin D receptor ; VDRE ; vitamin D responsive element ; GRE ; glucocor

刊名：Bioorganic and Medicinal Chemistry

出版年：2013

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