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内部出版物
在“
Elsevier电子期刊
”中,
命中:
25
条,耗时:小于0.01 秒
1.
Endothelin antagonism and uric acid levels in pulmonary arterial hypertension: Clinical associations
作者:
Neeraj Dhaun
;
MD
a
;
bean.dhaun@ed.ac.uk" class="auth_mail
;
Jean-Luc Vachiery
;
MD
b
;
Raymond L. Benza
;
MD
c
;
Robert Naeije
;
MD
b
;
Lie-Ju Hwang
;
PhD
d
;
Xuexuan Liu
;
MS
e
;
Simon Teal
;
BSc
f
;
David J. Webb
;
MD
;
FRCP
a
关键词:
6-minute walk distance
;
bosentan
;
hyperuricemia
;
pulmonary arterial hypertension
;
sitaxentan
;
uric acid
刊名:The Journal of Heart and Lung Transplantation
出版年:May, 2014
2.
Evaluation of
sitaxentan
(Thelin?) toxicity in juvenile rats and regulatory interactions during the development of a European Medicines Agency pediatric investigation plan
作者:
David M. Cross
;
Mazin Derzi
;
Elizabeth Horsley
;
Keith Owen
;
Fiona L. Stavros
关键词:
Sitaxentan
;
Juvenile
;
Rat
;
Toxicity
;
European Medicines Agency
;
Perinatal
;
Postnatal
;
Hepatotoxicity
;
Testicular toxicity
;
Pediatric investigation plan
刊名:Regulatory Toxicology and Pharmacology
出版年:2012
3.
An overview of the preclinical toxicity and potential carcinogenicity of
sitaxentan
(Thelin?), a potent endothelin receptor antagonist developed for pulmonary arterial hypertension
作者:
Keith Owen
;
David M. Cross
;
Mazin Derzi
;
Elizabeth Horsley
;
Fiona L. Stavros
关键词:
ALP
;
alkaline phosphatase
;
ALT
;
alanaine aminotransferase
;
APTT
;
activated partial thromboplastin time
;
AST
;
aspartate aminotransferase
;
AUC
;
area under the curve
;
BID
;
twice daily
;
BSEP
;
bile salt export pump
;
CMC
;
carboxymethylcellulose
;
DILI
;
drug-indu
刊名:Regulatory Toxicology and Pharmacology
出版年:2012
4.
Hepatotoxicidad en pacientes tratados con antagonistas del receptor de la endotelina: revisi贸n sistem谩tica y metaan谩lisis de ensayos cl铆nicos aleatorizados
作者:
Diego Mací
;
as Saint-Gerons
a
;
dmacias.sg@gmail.com" class="auth_mail
;
diegomac3@hotmail.com" class="auth_mail
;
Cé
;
sar de la Fuente Honrubia
a
;
Dolores Montero Corominas
a
;
Ferrá
;
n Catalá
;
-Ló
;
pez
a
;
b
;
c
关键词:
Bosentá
n ;
Ambrisentá
n ;
Sitaxentá
n ;
Sitaxsentá
n ;
Ensayo clí
;
nico aleatorizado y controlado
;
Metaaná
;
lisis
;
Reacció
;
n hepá
;
tica
;
Hepatotoxicidad
;
Dañ
;
o hepá
;
tico
刊名:Medicina Clínica
出版年:22 April, 2014
5.
Comparison of human ET
A
and ET
B
receptor signalling via G-protein and ¦Â-arrestin pathways
作者:
Janet J. Maguire
;
Rhoda E. Kuc
;
Victoria R. Pell
;
Andrew Green
;
Mike Brown
;
Sanj Kumar
;
Tom Wehrman
;
Elizabeth Quinn
;
Anthony P. Davenport
关键词:
ETA
;
ETB
;
Endothelin
;
¦Â-arrestin recruitment
;
Vasoconstriction
;
Human pharmacology
;
Human left ventricle
;
Sitaxentan
;
Ambrisentan
;
BQ123
;
BQ788
;
Biased agonist
;
Biased antagonist
刊名:Life Sciences
出版年:2012
6.
What is the best method of proteinuria measurement in clinical trials of endothelin receptor antagonists?
作者:
Jonathan D. Towler
;
Neeraj Dhaun
;
Margaret MacDougall
;
Vanessa Melville
;
Jane Goddard
;
David J. Webb
关键词:
Protein&ndash
;
creatinine ratio
;
Albumin&ndash
;
creatinine ratio
;
Endothelin receptor antagonists
;
Sitaxentan
;
Chronic kidney disease
;
Hypertension
刊名:Life Sciences
出版年:2012
7.
Nrf2 activation: A potential strategy for the prevention of acute mountain sickness
作者:
Christina Lisk
;
Joe McCord
;
Swapan Bose
;
Tim Sullivan
;
Zoe Loomis
;
Eva Nozik-Grayck
;
Thies Schroeder
;
Karyn Hamilton
;
David C. Irwin
关键词:
Nrf2
;
High altitude sickness
;
Cerebral
;
Vascular leak
;
Calcium channel blockers
;
Carbon anhydrase inhibitors
;
Endothelin receptor antagonist
;
Free radicals
刊名:Free Radical Biology and Medicine
出版年:2013
8.
Combination of
sitaxentan
and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan
作者:
S. Faruqi
;
H. Fathi
;
A.H. Morice
关键词:
Pulmonary arterial hypertension
;
Endothelin receptor antagonists
;
Phosphodiesterase-5 inhibitors
刊名:International Journal of Cardiology
出版年:2010
9.
Endothelin receptor antagonists ?their role in pulmonary medicine
作者:
S. Boniface
a
;
M. Reynaud-Gaubert
b
;
c
;
MartineLouise.REYNAUD@ap-hm.fr
关键词:
Pulmonary arterial hypertension
;
Endothelin-receptor antagonists
;
Bosentan
;
Ambrisentan
;
Sitaxentan
;
Pulmonary fibrosis
刊名:Revue des Maladies Respiratoires
出版年:2011
10.
Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ET
B
knockout mice
作者:
Lowell Ling
;
Rhoda E. Kuc
;
Janet J. Maguire
;
Neil J. Davie
;
David J. Webb
;
Paul Gibbs
;
Graeme J.M. Alex
;
er
;
Anthony P. Davenport
关键词:
Endothelin receptors
;
ETA ETB
;
Liver
;
Hepatotoxicity
;
Antagonist
;
Portal hypertension
;
Sitaxentan
;
Ambrisentan
刊名:Life Sciences
出版年:2012
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