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在“Elsevier电子期刊”中，命中：1,415条，耗时：小于0.01 秒

在所有数据库中总计命中：930条

1.Synthesis, anti-proliferative activity, SAR study, and preliminary in vivo toxicity study of substituted N,N′-bis(arylmethyl)benzimidazolium salts against a panel of non-small cell lung cancer cell lines

作者：Kerri L. Shelton^a ; Michael A. DeBord^a ; Patrick O. Wagers ; Marie R. Southerland ; Travis M. Williams ; Nikki K. Robishaw ; Leah P. Shriver ; Claire A. Tessier ; Matthew J. Panzner ; Wiley J. Youngs ; ^{youngs@uakron.edu}

关键词：NCI ; National Cancer Institute ; IC50 ; inhibitory concentration 50% ; NSCLC ; non-small cell lung cancer ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; SAR ; structure-activity relationship ; GI50 ; growth inhibition 50% ; TGI ; total growth inhibition ; LC50 ; lethal concentration 50% ; DTP ; Developmental Therapeutics Program ; 2-HPβCD ; 2-hydropropyl-β-cyclodextrin

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells

作者：Lei Tao^a ; ¹ ; Libing Wei^b ; ¹ ; Yishi Liu^a ; Yang Ding^a ; Xiuting Liu^a ; Xin Zhang^a ; Xiaoping Wang^b ; Yuyuan Yao^b ; Jinrong Lu^c ; Qing Wang^d ; ^{wxwqnj@hotmail.com} ; Rong Hu^a ; ^{ronghu@cpu.edu.cn}

关键词：BCA ; bicinchoninic acid ; Cyt c ; cytochrome c ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DCFH/DA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; DMSO ; dimethylsulfoxide ; FBS ; Fetal bovine serum ; HKII ; hexokinase II ; LDHA ; lactate dehydrogenase ; MMP ; mitochondrial membrane potential ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NAC ; N-acetylcysteine ; OXPHOS ; oxidative phosphorylation ; PARP ; poly (ADP-ribose) polymerase ; PBS ; phosphate buffered saline ; PFK ; 6-phospho

刊名：Biochemical Pharmacology

出版年：2017

3.Characterization of bioactive constituents from the gum resin of Gardenia lucida and its pharmacological potential

作者：Priyanka Maurya^a ; ^b ; ¹ ; Shilpi Singh^b ; ¹ ; Madan Mohan Gupta^a ; Suaib Luqman^b ; ^c ; ^{s.luqman@cimap.res.in}

关键词：DPPH ; 2 ; 2-diphenyl-1-picryl hydrazyl ; GAE ; gallic acid equivalent ; FRAP ; ferric reducing antioxidant power ; FSE ; ferrous sulphate equivalent ; QCE ; quercetin equivalent ; AAE ; ascorbic acid equivalent ; MTT dye ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; DMEM ; Dulbecco&rsquo ; s modified essential eagle medium ; FBS ; fetal bovine serum ; ODC ; ornithine decarboxylase ; CATD ; cathepsin D ; SDH ; succinate dehydrogenase ; PDB ; protein data bank ; PEP ; pepstatin A ; DFMO ; difluoromethylorni

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Mitochondrial functions of THP-1 monocytes following the exposure to selected natural compounds

作者：Nadin Schultze^a ; ^{nadin.schultze@uni-greifswald.de} ; Heike Wanka^b ; Paula Zwicker^a ; Ulrike Lindequist^a ; Beate Haertel^a

关键词：CBD ; cannabidiol ; CsA ; cyclosporine A ; DON ; deoxynivalenol ; ETC ; electron transport chain ; FCCP ; carbonyl cyanide-4 (trifluoromethoxy) phenylhydrazone ; IC10 ; inhibitory concentration 10 ; IC50 ; inhibitory concentration 50 ; MTT ; 3-(4 ; 5-dimethylthiazolyl-2)-2 ; 5-diphenyltetrazolium bromide ; OCR ; oxygen consumption rate ; RSC ; respiratory spare capacity

刊名：Toxicology

出版年：2017

5.Effect of abemaciclib (LY2835219) on enhancement of chemotherapeutic agents in ABCB1 and ABCG2 overexpressing cells in vitro and in vivo

作者：Tong Wu^a ; ^b ; Zhen Chen^b ; Kenneth K.W. To^c ; Xiaona Fang^b ; Fang Wang^b ; Bin Cheng^a ; ¹ ; ^{chengbin@mail.sysu.edu.cn} ; Liwu Fu^b ; ¹ ; ^{Fulw@mail.sysu.edu.cn}

关键词：MDR ; multidrug resistance ; DOX ; doxorubicin ; Rho 123 ; rhodamine 123 ; ABC ; adenosine triphosphate (ATP)-binding cassette ; ABCB1 ; ABC transporter subfamily B member 1 ; ABCG2 ; ABC transporter subfamily G member 2 ; CDK ; cyclin D-cyclin dependent kinase ; Rb ; retinoblastoma ; VRP ; verapamil ; FTC ; fumitremorgin C ; MTT ; 3-(4 ; 5-dimethylthiazol-2yl)-2 ; 5-diphenyltetrazoliumbromide ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DMSO ; dimethyl sulfoxide ; PCR ; polymerase chain reaction ; IAAP ; iodoaryla

刊名：Biochemical Pharmacology

出版年：2017

6.Assessment of cell viability and permeation enhancement in presence of lipid-based self-emulsifying drug delivery systems using Caco-2 cell model: Polysorbate 80 as the surfactant

作者：Pengli Bu^a ; ^b ; Yue Ji^b ; Silpa Narayanan^a ; Damon Dalrymple^c ; Xingguo Cheng^a ; Abu T.M. Serajuddin^a ; ^{serajuda@stjohns.edu}

关键词：LBDDS ; lipid-based drug delivery system ; LBSEDDS ; lipid-based self-emulsifying drug delivery system ; SEDDS ; self-emulsifying drug delivery system ; SMEDDS ; self-microemulsifying drug delivery system ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; PG ; propylene glycol ; HBSS ; Hank's Balanced Salt Solution ; DMEM ; Dulbecco's Modification of Eagle's Medium ; FBS ; fetal bovine serum ; DMSO ; dimethyl sulfoxide ; TEER ; transepithelial electrical resistance

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

7.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

8.A simple and highly effective catalytic nanozyme scavenger for organophosphorus neurotoxins

作者：Elena N. Efremenko^a ; ^{elena_efremenko@list.ru} ; Ilya V. Lyagin^a ; Natalia L. Klyachko^a ; ^b ; Tatiana Bronich^a ; ^c ; Natalia V. Zavyalova^d ; Yuhang Jiang^b ; Alexander V. Kabanov^a ; ^b ; ^c ; ^{kabanov@unc.edu}

关键词：Acetylthiocholine chloride (PubChem CID ; 22411) ; 5 ; 5&prime ; -dithiobis(2-nitrobenzoic acid) (PubChem CID ; 6254) ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide (PubChem CID ; 64965) ; Paraoxon (PubChem CID ; 9395) ; Parathion (PubChem CID ; 991) ; Parathion-methyl (PubChem CID ; 4130) ; VX (PubChem CID ; 39793)

刊名：Journal of Controlled Release

出版年：2017

9.In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death

作者：Mathieu Vinken^a ; ^{mvinken@vub.ac.be} ; Bas J. Blaauboer^b

关键词：AO(P) ; adverse outcome (pathway) ; ATP ; adenosine triphosphate ; DMSO ; dimethylsulfoxide ; DNA ; deoxyribonucleic acid ; KE ; key event ; LDH ; lactate dehydrogenase ; MIE ; molecular initiating event ; MTP ; mitochondrial permeability transition ; MTT ; [3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide] ; NADH ; nicotinamide adenine dinucleotide

刊名：Toxicology in Vitro

出版年：2017

10.Resveratrol attenuates MPP⁺-induced mitochondrial dysfunction and cell apoptosis via AKT/GSK-3β pathway in SN4741 cells

作者：Weijun Zeng^a ; ¹ ; Wei Zhang^b ; ^c ; ¹ ; Fangfang Lu^a ; Li Gao^a ; Guodong Gao^a ; ^{gaogd1954@163.com}

关键词：Res ; Resveratrol ; MPP+ ; 1-methyl-4-phenylpyridinium ; PD ; Parkinson&rsquo ; s disease ; GSK-3 ; Glycogen synthase kinase-3 ; GSK-3β ; Glycogen synthase kinase-3 beta ; AKT ; Protein kinase B ; MMP ; Mitochondrial membrane potential ; PI3K ; Phosphatidylinositol 3-kinase ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MTT ; 3-(4 ; 5-dimethylthiazol-2yl)-2 ; 5-diphenyltetrazolium bromide

刊名：Neuroscience Letters

出版年：2017

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